Immunology News and Research

Latest Immunology News and Research

Older melanoma patients fare better on immune checkpoint blockade therapy

Patient age correlates with response to immunotherapy in melanoma and depleting regulatory T cells in young patients may have a therapeutic potential to enhance response in younger patients, according to research from The Wistar Institute. Study results were published online in Clinical Cancer Research.

13 Jun 2018

Novel approach induces cell death via dual targeting of DNA repair mechanism

Proteins commonly known as BRCA - short for BReast CAncer susceptibility gene- serve a critical role in cellular DNA repair, but when mutated they allow genetic errors to replicate, facilitating cancer development.

13 Jun 2018

Cureworks collaborative aims to accelerate development of immunotherapies for pediatric cancer

Seattle Children's, with participating members Children's National Health System, BC Children's Hospital and Children's Hospital Los Angeles, has launched CureWorks, an international collaborative of leading academic children's hospitals determined to accelerate the development of immunotherapy treatments for childhood cancer.

12 Jun 2018

Immune response in RA patients linked to inflammation and joint damage

To diagnose rheumatoid arthritis, antibodies to the amino acid citrulline are commonly measured. A new study from Uppsala University shows that a broad mix of different antibodies in the joints is the dominant factor that can be associated with severe inflammation and joint damage.

12 Jun 2018

Naturally occurring antibody can block inflammation in mice, finds study

Researchers at University of California San Diego School of Medicine discovered that they can block inflammation in mice with a naturally occurring antibody that binds oxidized phospholipids, molecules on cell surfaces that get modified by inflammation.

7 Jun 2018

Study finds how colon cancer alters its genes to escape the immune system

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.

6 Jun 2018

Study: Older asthma patients are happier when they have a say in their medical care

It's clear an increasing number of people want a say in their medical care. A new study shows older people with asthma are among those no longer content to say, "Up to you, Doc" and then wait to be told how to move forward with their care.

6 Jun 2018

New way of delivering gene therapy shows promise in treating brain conditions

Researchers from the School of Immunology & Microbial Sciences have engineered a novel way of delivering gene therapy that they hope will mean scientists and doctors can target areas of the brain that were previously difficult to reach.

5 Jun 2018

Scientists reveal role of lung scavenger cells in liver cancer spread to the lungs

Hepatocellular carcinoma is the most common form of liver cancer, and the third biggest cause of death from cancer worldwide.

4 Jun 2018

Discovering Antibodies with Universal Specificity

Professor Hedda Wardemann discusses our current knowledge of antibody specificity and how her research team are challenging this, through the discovery of anti-bacterial antibodies with universal specificity.

1 Jun 2018

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Treating inflammatory diseases of the bowel is extremely challenging: Genes, gut microbes and disrupted immune function all contribute.

31 May 2018

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Like exposing a crime boss whose authority has gone undetected, St. Jude Children's Research Hospital scientists have identified a hidden driver that influences production of the T cells that fight cancer and infections. The study appears today as an advance online publication in the journal Nature.

31 May 2018

Study provides guidance to determine the right treatment for Red Diaper Syndrome

A case study and subsequent literature review has concluded that absent signs of clinical infection, breastfeeding should continue normally when mother and baby are diagnosed with Red Diaper Syndrome caused by Serratia marcescens, an opportunistic bacteria.

30 May 2018

Defective energy production may explain why our brains are prone to age-related diseases

Defective energy production in old neurons might explain why our brains are so prone to age-related diseases.

30 May 2018

Researchers discover cascade of immune processes linked to poor outcomes in aggressive breast cancer

Cancer is crafty. To survive and thrive, tumors find a way of thwarting our body's natural systems.

24 May 2018

Allergies can have serious, far-reaching consequences on adolescents

Although allergies affect more than 50 million Americans, they are occasionally misunderstood and can be seen as a minor condition. An article published in Annals of Allergy, Asthma and Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology shows allergies can have serious, far-reaching consequences, especially on adolescent sufferers.

24 May 2018

Penn investigators discover source of immune molecule involved in nasal polyps, asthma

A new discovery about how the immune system responds to common sinus infections and asthma could explain why patients develop these issues in the first place and ultimately may lead to improved targeted therapies.

23 May 2018

Celgene to share new and updated data around novel hematological therapies

Celgene Corporation today announced that data from a broad range of early and late stage studies evaluating Celgene investigational agents and investigational uses of marketed products will be presented at the 23rd European Hematology Association annual meeting in Stockholm, Sweden, from June 14-17, 2018.

22 May 2018

Researchers discover link between tuberculosis and Parkinson's disease

The mechanism our immune cells use to clear bacterial infections like tuberculosis (TB) might also be implicated in Parkinson's disease, according to a new collaborative study led by the Francis Crick Institute, Newcastle University and GSK.

22 May 2018

Researchers uncover clues to early lung transplant failure

Among organ transplant patients, those receiving new lungs face a higher rate of organ failure and death compared with people undergoing heart, kidney and liver transplants. One of the culprits is inflammation that damages the newly transplanted lung.

22 May 2018

Immunology News and Research

Latest Immunology News and Research

Older melanoma patients fare better on immune checkpoint blockade therapy

Novel approach induces cell death via dual targeting of DNA repair mechanism

Cureworks collaborative aims to accelerate development of immunotherapies for pediatric cancer

Immune response in RA patients linked to inflammation and joint damage

Naturally occurring antibody can block inflammation in mice, finds study

Study finds how colon cancer alters its genes to escape the immune system

Study: Older asthma patients are happier when they have a say in their medical care

New way of delivering gene therapy shows promise in treating brain conditions

Scientists reveal role of lung scavenger cells in liver cancer spread to the lungs

Discovering Antibodies with Universal Specificity

Researchers trigger natural defense mechanism to alleviate intestinal inflammation

Scientists identify 'hidden' driver that helps prime the anti-tumor immune response

Study provides guidance to determine the right treatment for Red Diaper Syndrome

Defective energy production may explain why our brains are prone to age-related diseases

Researchers discover cascade of immune processes linked to poor outcomes in aggressive breast cancer

Allergies can have serious, far-reaching consequences on adolescents

Penn investigators discover source of immune molecule involved in nasal polyps, asthma

Celgene to share new and updated data around novel hematological therapies

Researchers discover link between tuberculosis and Parkinson's disease

Researchers uncover clues to early lung transplant failure

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