Immunology News and Research

Latest Immunology News and Research

New guideline for the evaluation and testing of patients with penicillin allergies

A new guideline published in Clinical & Experimental Allergy will help clinicians evaluate and test patients for potential penicillin allergies.

21 Sep 2022

Researchers devise rules for a faster, more effective way to identify tuberculosis treatments

Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year.

21 Sep 2022

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

Scientists have shown how tumour cells evade immunotherapy by generating unique, temporary cell-in-cell structures, where the inner cells remain in tact and can return to single tumour cells.

20 Sep 2022

FDA-approved anti-sedative could alleviate common side effects of cancer treatments

Researchers in China have discovered that inhibiting a protein called the GABAA receptor can protect intestinal stem cells from the toxic effects of chemotherapy and radiotherapy.

20 Sep 2022

UTHSC-led researchers receive $5.2 million to study obesity-mediated cancer risk

The National Cancer Institute has awarded more than $5.2 million to a team lead by researchers from the University of Tennessee Health Science Center for a study that will fill critical gaps in knowledge around obesity-mediated cancer risk.

20 Sep 2022

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

Mohsan Saeed, PhD, assistant professor of biochemistry at Boston University School of Medicine (BUSM), has received a five-year, $2 million R35 grant from the National Institute of General Medical Sciences, as well as a five-year, $2.5 million R01 grant from the National Institute of Allergy and Infectious Diseases.

20 Sep 2022

High-fat diets drive the production of inflammatory immune cells in the bone marrow of mice

Scientists have shown that high-fat diets can cause rapid changes in the bone marrow of mice, driving the production of inflammatory immune cells, according to findings published today in eLife.

20 Sep 2022

Collaborative network wins $8 million grant to identify biomarkers for acute rheumatic fever

A collaborative network led by Cincinnati Children's Hospital Medical Center has received an $8 million grant from the Leducq Foundation to fund a project that will look to identify and validate biomarkers for acute rheumatic fever (ARF).

19 Sep 2022

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Immune checkpoint inhibitor (ICI) therapy is a type of treatment for melanoma, the deadliest form of skin cancer, which blocks proteins on tumor or immune cells that prevent the immune system from killing cancer cells.

19 Sep 2022

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

If a secretion in the lungs’ alveoli is not cleared regularly, breathing difficulties can develop. In a study published in Science Immunology, a team led by Alexander Mildner and Achim Leutz has now explained the pivotal role of the transcription factor C/EBPb in this process.

16 Sep 2022

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

Children with certain immunodeficiency diseases carry mutations in genes that regulate the body's immune system against viral infections and they have a higher mortality rate due to COVID-19.

16 Sep 2022

New genomic test can predict a patient's risk of developing severe COVID-19, research suggests

A genomic test being developed by a Charlottesville, Va., company can predict a patient's risk of developing severe COVID-19, new research from UVA Health suggests.

16 Sep 2022

Father of modern corneal science honored with the 2022 António Champalimaud Vision Award

Claes H. Dohlman, MD, PhD, whose pioneering research at Mass Eye and Ear and in the Department of Ophthalmology at Harvard Medical School (HMS) has forever changed the way conditions of the cornea are understood and treated, has been presented with the 2022 António Champalimaud Vision Award for his vast contributions to vision research.

15 Sep 2022

BU researcher awarded $7.2 million grant to develop mAb-based contraceptive products

Deborah Jean Anderson, PhD, professor of medicine at Boston University School of Medicine, has received a four-year, $7.2 million grant from the NIH's National Institute of Child Health and Human Development renewing support for a Contraceptive Research Center at BUSM to further her research to develop innovative monoclonal antibody (mAb)-based contraceptive and multipurpose prevention technology (MPT) products.

15 Sep 2022

Tufts researchers use machine learning to identify new drug cocktails against tuberculosis

Imagine you have 20 new compounds that have shown some effectiveness in treating a disease like tuberculosis (TB), which affects 10 million people worldwide and kills 1.5 million each year.

14 Sep 2022

Study identifies mechanism behind 'cytokine storm' in COVID-19 patient lungs

A new study by HSS Research Institute scientists identifies a mechanism by which SARS-CoV-2 induces the inflammatory response in COVID-19 patient lungs, so-called "cytokine storm", that can lead to lasting tissue damage and poor patient outcomes.

13 Sep 2022

Research could lead to a new therapeutic option for patients with bladder cancer

Mount Sinai researchers have made two important discoveries about the mechanism by which bladder cancer cells foil attacks from the immune system.

12 Sep 2022

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

A novel treatment strategy with personalized cell therapy significantly improves progression-free survival compared to standard immunotherapy in patients with advanced melanoma, according to ground-breaking results reported at the ESMO Congress 2022 from the phase 3 M14TIL trial.

12 Sep 2022

Weill Cornell Medicine receives $5 million NIH grant for next generation TB research

Weill Cornell Medicine has been awarded a five-year, $5 million grant from the National Institutes of Allergy and Infectious Diseases of the National Institutes of Health to establish a new multi-institutional center for tuberculosis (TB) research and training the next generation of TB investigators.

9 Sep 2022

Potential HIV vaccine component leads to strong protection in primates

To block infection from HIV, a successful vaccine will require a combination of ingredients, including at least three antibody targets and a substance that boosts immune responses.

9 Sep 2022

Immunology News and Research

Latest Immunology News and Research

New guideline for the evaluation and testing of patients with penicillin allergies

Researchers devise rules for a faster, more effective way to identify tuberculosis treatments

Tumors generate unique, temporary cell-in-cell structures to evade immunotherapy

FDA-approved anti-sedative could alleviate common side effects of cancer treatments

UTHSC-led researchers receive $5.2 million to study obesity-mediated cancer risk

BU investigator wins highly competitive awards to study the role of proteases in regulation of cellular defenses

High-fat diets drive the production of inflammatory immune cells in the bone marrow of mice

Collaborative network wins $8 million grant to identify biomarkers for acute rheumatic fever

Research uncovers novel predictors of immune checkpoint inhibitor therapy for melanoma

Research reveals pivotal role of C/EBPb in the development of alveolar macrophages

Mortality risk higher among children with primary immunodeficiency diseases infected with SARS-CoV-2

New genomic test can predict a patient's risk of developing severe COVID-19, research suggests

Father of modern corneal science honored with the 2022 António Champalimaud Vision Award

BU researcher awarded $7.2 million grant to develop mAb-based contraceptive products

Tufts researchers use machine learning to identify new drug cocktails against tuberculosis

Study identifies mechanism behind 'cytokine storm' in COVID-19 patient lungs

Research could lead to a new therapeutic option for patients with bladder cancer

Tumor-infiltrating lymphocytes therapy treats cancers at a large scale

Weill Cornell Medicine receives $5 million NIH grant for next generation TB research

Potential HIV vaccine component leads to strong protection in primates

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