Immunology News and Research

Latest Immunology News and Research

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Supporting actors sometimes steal the show. In a new study published today in Cell, researchers headed by Prof. Ido Amit at the Weizmann Institute of Science have shown that supporting cells called fibroblasts, long viewed as uniform background players, are in fact extremely varied and vital.

5 Apr 2022

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

The rules to the kids' game "red light, green light" are easy to follow: red always means stop, and green always means go. But now, researchers from Japan have found that a key protein involved in B cell signaling acts as both a red light to signaling in healthy cells and a green light to signaling in immune-deficient cells.

4 Apr 2022

The effect of COVID-19 on the lung function of young adults

Researchers evaluate whether SARS-CoV-2 infection has a negative impact on lung function in young adults who experienced mild to moderate COVID-19.

3 Apr 2022

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Scientists at Northwestern Medicine are using new advances in CRISPR gene-editing technology to uncover new biology that could lead to longer-lasting treatments and new therapeutic strategies for Human Immunodeficiency Virus (HIV).

1 Apr 2022

Tulane researchers show how COVID-19 affects the central nervous system

COVID-19 patients commonly report having headaches, confusion and other neurological symptoms, but doctors don't fully understand how the disease targets the brain during infection.

1 Apr 2022

Study finds COVID-19 convalescent children had more robust humoral immune responses to SARS-CoV-2 than convalescent adults

The work investigated why the children experienced milder COVID-19 illness even after a strong immune response.

1 Apr 2022

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

Faculty from the Departments of Microbiology, Medicine Genetics and Genomic Sciences, and Pathology and Molecular Cell-Based Medicine at the Icahn School of Medicine at Mount Sinai play key roles in a National Institutes of Health (NIH) program set up to provide a real-time risk assessment of variants of SARS-CoV-2, the virus that causes COVID-19. The program, called SARS-CoV-2 Assessment of Viral Evolution (SAVE) and described in a paper published March 31 in Nature, assesses how the variants might affect transmission, virulence, and resistance to both disease-induced (convalescent) and vaccine-induced immunity.

31 Mar 2022

$2.05 million to support UTHSC's advanced genetics project on breast cancer

A University of Tennessee Health Science Center team has received $2.05 million from the National Cancer Institute for an advanced genetics project that could help develop targeted therapies and personalized treatment for breast cancer. Liza Makowski, PhD, professor of Hematology and Oncology in the College of Medicine, is the lead investigator on the award.

31 Mar 2022

Role of SARS-CoV-2 S1 subunit in severe COVID-19

A new study aimed to determine whether portions of the SARS-CoV-2 spike protein are capable of activating innate immune cells like Gal-3.

30 Mar 2022

SARS-CoV-2 and pandemic chilblains

Researchers evaluate the pathophysiological relationship between COVID-19 and pandemic-associated chilblain lesions.

30 Mar 2022

A ferritin nanoparticle candidate vaccine for COVID

In a recent study published on the bioRxiv* preprint server, the immunogenicity, and effectiveness of SARS-CoV-2 spike ferritin nanoparticle (SpFN) adjuvanted with aluminum hydroxide (AlOH3) or Army Liposomal Formulation QS-21 (ALFQ) in a cynomolgus macaque (CM) COVID-19 model was evaluated.

30 Mar 2022

New tissue-clearing method could speed the study of many disease-related biological processes

Scientists at Scripps Research have unveiled a new tissue-clearing method for rendering large biological samples transparent.

29 Mar 2022

The different actions of CBD in SARS-CoV-2 infection

An article has described the role of cannabidiol as a potential inhibitor of hyperinflammation in SARS-CoV-2 infection.

29 Mar 2022

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

A recent viewpoint illustrated that evaluating T cell responses to COVID-19 is essential to inform public health initiatives.

29 Mar 2022

New compound delivered in a nasal spray effectively treats delta variant infection in mice

Researchers have shown a new compound delivered in a nasal spray is highly effective in preventing and treating COVID-19 caused by the Delta variant in mice.

29 Mar 2022

One year after severe COVID-19, T cells persist against SARS-CoV-2

In a recently published article in the journal eBioMedicine, scientists have demonstrated that critically ill coronavirus disease 2019 (COVID-19) patients are capable of generating durable memory T cell response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) for more than one year after hospital discharge.

28 Mar 2022

Depression occurs independently of inflammation for many older people, study suggests

Multiple prior studies have found higher levels of inflammation in older individuals with depression. Now, a new Penn Medicine study has found that clinically depressed older individuals, on average, don't have elevated levels of inflammation if they don't already have other inflammatory conditions such as arthritis.

28 Mar 2022

New insights into SARS-CoV-2 immunity gained from natural infection

Antibody-secreting cells (ASCs) peaked at 3-4 weeks and were still being produced at 3-4 months in patients hospitalized with COVID-19, according to a study published in the peer-reviewed journal Viral Immunology.

25 Mar 2022

New implantable biotechnology produces and releases CAR-T cells for attacking tumors

Researchers from North Carolina State University and the University of North Carolina at Chapel Hill have developed an implantable biotechnology that produces and releases CAR-T cells for attacking cancerous tumors.

24 Mar 2022

New therapy makes immunologically 'cold' tumors hot enough for immune attack

Pancreatic cancer is notoriously difficult to cure or even treat. Now, a new strategy devised by scientists at Albert Einstein College of Medicine has succeeded in making pancreatic tumors visible to the immune systems of mice and vulnerable to immune attack, reducing cancer metastases by 87%.

23 Mar 2022

Immunology News and Research

Latest Immunology News and Research

A critical subset of fibroblasts may lie at the origins of rare autoimmune disease

Key protein could be a novel target for treatment of patients with B cell signaling deficiencies

The effect of COVID-19 on the lung function of young adults

Scientists use new CRISPR gene-editing approach to find paths toward possible HIV cure

Tulane researchers show how COVID-19 affects the central nervous system

Study finds COVID-19 convalescent children had more robust humoral immune responses to SARS-CoV-2 than convalescent adults

NIH program provides a real-time risk assessment of variants of SARS-CoV-2

$2.05 million to support UTHSC's advanced genetics project on breast cancer

Role of SARS-CoV-2 S1 subunit in severe COVID-19

SARS-CoV-2 and pandemic chilblains

A ferritin nanoparticle candidate vaccine for COVID

New tissue-clearing method could speed the study of many disease-related biological processes

The different actions of CBD in SARS-CoV-2 infection

Viewpoint explains how T cell testing can help research on population-level SARS-CoV-2 adaptive immunity and inform public health policies

New compound delivered in a nasal spray effectively treats delta variant infection in mice

One year after severe COVID-19, T cells persist against SARS-CoV-2

Depression occurs independently of inflammation for many older people, study suggests

New insights into SARS-CoV-2 immunity gained from natural infection

New implantable biotechnology produces and releases CAR-T cells for attacking tumors

New therapy makes immunologically 'cold' tumors hot enough for immune attack

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