Juvenile Diabetes News and Research

Latest Juvenile Diabetes News and Research

Islet cell trasnplant without immunosuppressive drugs successful in mice

Scientists at Weill Cornell Medical College may have reached a breakthrough in the search for a lasting cure for type 1 diabetes.

11 Mar 2007

Artificial pancreas promises to transform life for young diabetics

A team of scientists in Britain are in the process of developing an artificial pancreas for children and teens with type 1 diabetes.

8 Nov 2006

Researchers identify genetic risk for type 1 diabetes

A discovery at the Barbara Davis Center for Childhood Diabetes has identified a genetic risk for type 1 diabetes three to four times higher than previously thought possible.

4 Sep 2006

Enrichment of regulatory CD4+CD25+ T cells by inhibition of phospholipase D signaling

A signaling molecule with an affinity for alcohol has yielded a rapid, inexpensive way to make large numbers of immune cells that work like beat cops keeping misguided cells from attacking the body.

8 Aug 2006

Combinatorial approach found to reverse the onset of type 1 diabetes

A major finding, which represents an important step toward a potential cure for type 1 (insulin-dependent) diabetes, has been made by a research team at the La Jolla Institute for Allergy & Immunology (LIAI). The team, led by Matthias von Herrath, M.D., an internationally recognized expert on the molecular basis of type 1 diabetes, used a combinatorial treatment approach in laboratory mice and found it reversed recent onset type 1 diabetes in the majority of animals tested.

28 Apr 2006

Approval of integrated insulin pump and continuous glucose system a significant step towards artificial pancreas technology

The Juvenile Diabetes Research Foundation (JDRF) has said that the federal government's approval of an insulin pump that also provides real-time, continuous glucose monitoring is a significant step on the path to the development of an artificial pancreas, with the potential to significantly improve diabetes care and lower the risk of complications.

13 Apr 2006

Researchers reverse juvenile diabetes in animal model

Groundbreaking human clinical trial for type 1 diabetes to start this spring in Pittsburgh - Children's Hospital of Pittsburgh of UPMC researchers reverse juvenile diabetes in animal model; Phase 1 clinical trial approved by FDA.

4 Apr 2006

Study provides a boost for efforts to reverse type-1 diabetes

Researchers have been able to confirm most but not all of the results of a high-profile study that brought new hope to diabetes patients. This study provides a boost for efforts to reverse type-1 diabetes in recently diagnosed patients but not for efforts to grow new islets from spleens.

27 Mar 2006

University of Calgary researchers develop bioreactor procedures to grow pancreatic cells in their laboratory

Freedom from insulin injections and the myriad of health problems related to type 1 diabetes is closer to becoming reality, thanks to University of Calgary researchers who are developing the first bioreactor procedures to grow pancreatic cells in their laboratory.

21 Mar 2006

Positive effects of tight blood glucose control can be seen more than a decade later in diabetics

People with diabetes who keep their blood sugar in check today will probably have a far lower chance of developing foot pain or other nerve damage tomorrow, according to new research results from a national study.

9 Mar 2006

Study may lead to ways to reduce heart attacks in diabetes patients

For people with type 2 diabetes, the death rate from a first heart attack is two to three times the death rate of patients without the disease. Similarly, patients with diabetes and ischemic (reduced blood flow) heart disease have a much higher mortality rate than the general population.

7 Mar 2006

Defective apoptosis of dendritic cells can be a critical component of autoimmune diseases

The failure of programming that sparks the death of dendritic cells - those that activate the immune system - can initiate autoimmune disease, said researchers from Baylor College of Medicine in a report that appears in the current issue of the journal Science.

1 Mar 2006

New generation gold-based drugs for treating rheumatoid arthritis

Gold compounds have been used for the treatment of rheumatoid arthritis and other autoimmune diseases for more than 75 years, but until now, how the metals work has been a mystery.

27 Feb 2006

Selective T cell stimulation could help improve treatment of autoimmune disease and cancer

The findings could also be significant for developing new ways to help patients with autoimmune diseases such as rheumatoid arthritis, multiple sclerosis, or juvenile diabetes.

23 Feb 2006

Diabetes gene found in 40% of population

Researchers in Iceland say they have identified a single genetic change which could predispose close to 40 percent of the population to type-2 diabetes.

16 Jan 2006

Brain plays a major role in the ability of insulin therapy to lower blood sugar in animals with diabetes

"Our findings suggest that, in individuals with diabetes, the ability of insulin to lower blood sugar involves the brain," said senior author of the study, Michael Schwartz of the University of Washington at Seattle. "This effect is not trivial; the brain makes a substantial contribution to insulin response."

10 Jan 2006