Melanoma

Melanoma is a form of cancer that begins in melanocytes (cells that make the pigment melanin). It may begin in a mole (skin melanoma), but can also begin in other pigmented tissues, such as in the eye or in the intestines.

What are Melanomas?

The treatment of melanoma may involve surgery, immunotherapy, targeted therapy, chemotherapy or radiotherapy, or a combination of several treatment techniques. Each of these treatments is outlined below.

Melanoma Symptoms and Cause

How is Melanoma Diagnosed and Treated?

Melanoma Prognosis

Melanoma Epidemiology

Melanoma History

Melanoma Research

Choroidal Melanoma

Managing Choroidal Melanomas

Malignant Melanoma

Metastatic Melanoma

Latest Melanoma News and Research

Immunotherapy treatment may be appropriate for patients with earlier stages of melanoma

An immunotherapy called pembrolizumab reduced cancer recurrence after surgery in patients with stage IIb and IIc melanoma, according to the results of an international, randomized phase III clinical trial led by UPMC Hillman Cancer Center.

20 Sep 2021

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

A specially designed lipid nanoparticle could deliver immune-signaling molecules into liver macrophage cells to overcome resistance to anti-tumor immunotherapy.

18 Sep 2021

Scientists identify new approach to overcome resistance to cancer immunotherapy

Hokkaido University scientists and colleagues in Japan have found a way that could help some patients overcome resistance to immunotherapy treatment for cancer. The approach, proven in mice experiments, was reported in the Journal for Immunotherapy of Cancer.

17 Sep 2021

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

New research led by the University of Birmingham suggests that skin cancer patients could have a better prognosis if their T cells send messages from five specific genes in their immune response to drugs given to treat the disease.

17 Sep 2021

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Hundreds of cancer-linked genes play a different role in causing disease than scientists had expected.

16 Sep 2021

Study highlights the importance of deeply exploring the immune responses against cancer

Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body's own immune system to destroy a tumor, by injecting fragments of cancer proteins found on the tumor.

16 Sep 2021

Study looks at drug resistance in BRAF-mutated gliomas

Looking to understand why some brain tumors with a specific mutation can start to reject drugs commonly used to treat them, CU Cancer Center member Jean Mulcahy Levy, MD, led researchers from institutions around the country -; including several from the University of Colorado School of Medicine -; to study samples of brain tumors before and after being treated with the drug.

16 Sep 2021

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

The University of Texas MD Anderson Cancer Center and SNIPR BIOME today announced a strategic collaboration to advance new CRISPR-based microbiome therapeutics to reduce immune-related adverse events (irAE) in patients being treated with combined immune checkpoint inhibitors.

13 Sep 2021

World-first 3D scanning technology could enable earlier detection of skin cancer

Queenslanders could have skin cancer diagnosed earlier using world-first 3D scanning technology with the launch of the Australian Cancer Research Foundation Australian Centre of Excellence in Melanoma Imaging and Diagnosis.

13 Sep 2021

Simple blood test enables early detection of immunotherapy-triggered encephalitis

Immunotherapy is very effective for many cancers, but the treatment can also cause autoimmune side effects. Encephalitis is one of the most serious and difficult-to-diagnose side effects of immunotherapy.

2 Sep 2021

UniSA researchers are putting cancer patients at the heart of clinical trials

From bench to bedside, the journey towards new cancer therapies is full of challenges. Clinical trials – where new treatments are tested on people – are vital, but with fewer than five per cent of cancer patients participating worldwide, it’s a long road to travel.

1 Sep 2021

The tale of mRNA vaccines: Turning calamity into opportunity

In a review paper published in the journal Nature Reviews, researchers from Carnegie Mellon University and the University of Pennsylvania have described the underlying technologies for mRNA vaccines and their future prospects with improved delivery systems and applications in diseases beyond the ongoing COVID-19 pandemic.

31 Aug 2021

Researchers study the role of low-density granulocytes in COVID-19

Information on granulocytes helps to understand mechanisms associated with covid-19 and other infectious diseases. Such information also promotes the development of better diagnostic methods and therapies.

30 Aug 2021

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

In recent years, immune-based treatments for cancer have buoyed the hopes of doctors and patients alike. Drugs called immune checkpoint inhibitors have provided lifesaving benefits to a growing list of people with several types of cancer, including melanoma, lung cancer, bladder cancer, and many more.

25 Aug 2021

Intestinal microorganisms help regulate anti-tumor immune responses to radiation therapy, study finds

Cedars-Sinai Cancer researchers have discovered that intestinal microorganisms help regulate anti-tumor immune responses to radiation treatments, and that fungi and bacteria have opposing effects on those responses.

24 Aug 2021

Study uncovers how breast cancer cells use cholesterol to overcome stress-induced death mechanism

Chronically high cholesterol levels are known to be associated with increased risks of breast cancer and worse outcomes in most cancers, but the link has not been fully understood.

24 Aug 2021

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Scientists Dr. Cristina Puig-Saus and Dr. Daniel Shin from the UCLA Jonsson Comprehensive Cancer Center have received a $1 million Translational Research Award from the U.S. Department of Defense Melanoma Research Program to help advance the use of chimeric antigen receptor, or CAR, T cell therapy as a treatment for people with acral, mucosal and uveal melanomas.

24 Aug 2021

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

Rice University faculty members led by bioengineer Gang Bao have been awarded a $4 million grant by the Cancer Prevention and Research Institute of Texas to establish the Genetic Design and Engineering Center.

20 Aug 2021

Study illuminates genetic understanding of aggressive childhood leukemias

New research published today in JAMA Oncology reports how two separate DNA changes appear to predict aggressive childhood leukemias when they occur in combination.

20 Aug 2021

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Patients with metastatic melanoma that had relapsed on anti-PD-1 therapies or BRAF/MEK inhibitors did not respond as well to an investigational therapy that involves the adoptive cell transfer of tumor-infiltrating lymphocytes (ACT-TIL) as patients naïve to these treatments.

19 Aug 2021

Melanoma

Overview

Melanoma Symptoms and Cause

How is Melanoma Diagnosed and Treated?

Melanoma Prognosis

Feature Articles

Melanoma Epidemiology

Melanoma History

Melanoma Research

Choroidal Melanoma

Managing Choroidal Melanomas

Malignant Melanoma

Metastatic Melanoma

Latest Melanoma News and Research

Immunotherapy treatment may be appropriate for patients with earlier stages of melanoma

Specially designed lipid nanoparticles overcome resistance to anti-tumor immunotherapy

Scientists identify new approach to overcome resistance to cancer immunotherapy

Skin cancer patients could have better prognosis with stronger T cell receptor signal strength

Defective versions of tumor suppressor genes can help cancer cells evade the immune system

Study highlights the importance of deeply exploring the immune responses against cancer

Study looks at drug resistance in BRAF-mutated gliomas

MD Anderson and SNIPR BIOME join forces to advance new CRISPR-based microbiome therapeutics

World-first 3D scanning technology could enable earlier detection of skin cancer

Simple blood test enables early detection of immunotherapy-triggered encephalitis

UniSA researchers are putting cancer patients at the heart of clinical trials

The tale of mRNA vaccines: Turning calamity into opportunity

Researchers study the role of low-density granulocytes in COVID-19

MSK researchers identify potential biomarker of response to checkpoint immunotherapy

Intestinal microorganisms help regulate anti-tumor immune responses to radiation therapy, study finds

Study uncovers how breast cancer cells use cholesterol to overcome stress-induced death mechanism

UCLA scientists receive $1 million translational award to advance CAR T cell therapy for rare melanomas

Rice University awarded $4 million CPRIT grant to establish Genetic Design and Engineering Center

Study illuminates genetic understanding of aggressive childhood leukemias

Prior treatment may impact efficacy of ACT-TIL in patients with metastatic melanoma

Next-Gen Sequencing And The Diagnosis of Disease

In-depth sequencing of SARS-CoV-2 variants crucial in controlling outbreaks

Increasing your risk of IBD through processed food

Melanoma

Overview

Feature Articles

Melanoma Epidemiology

Melanoma History

Melanoma Research

Choroidal Melanoma

Managing Choroidal Melanomas

Malignant Melanoma

Metastatic Melanoma

Latest Melanoma News and Research

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