Metabolic Syndrome

Metabolic syndrome is a clustering of abnormalities that includes obesity, hyperglycemia, high blood pressure, and atherogenic dyslipidemia. Advances in scientific knowledge, the increasing prevalence of obesity, and the disorder's role in contributing to cardiovascular disease and diabetes are fueling interest in metabolic syndrome.

What is Metabolic Syndrome?

Metabolic syndrome is a condition characterized by the presence diabetes, obesity and high blood pressure. These conditions increase the risk of cardiovascular illnesses such as stroke and heart disease. Individually, diabetes, high blood pressure and obesity can lead to vascular damage, but a combination of these illnesses is particularly dangerous.

History of Metabolic Syndrome

Metabolic Syndrome Risk Factors

Metabolic Syndrome Prevention

Metabolic Syndrome Treatment

Metabolic Syndrome and Bariatric Surgery

Polycystic Ovary Syndrome and Metabolic Syndrome

Abdominal Obesity and the Metabolic Syndrome

Latest Metabolic Syndrome News and Research

Exercise and omega-3 reduce oral inflammation in animal study

A study published in the journal Scientific Reports indicates that physical exercise combined with omega-3 supplementation considerably improves the immune response and reduces the severity of chronic apical periodontitis.

11 Jun 2025

Study explores the connection between abnormal uterine bleeding and hyperinsulinemia

Insulin resistance is becoming more common because of a combination of lifestyle factors, genetics, and medical conditions. A lot of those same risk factors play a role in abnormal uterine bleeding.

4 Jun 2025

Blood filtration may offer new hope for removing microplastics from the body

Researchers report the first evidence that therapeutic apheresis, a blood-filtration technique, can remove microplastic- and nanoplastic-like particles from humans with ME/CFS. While promising, further studies are needed to quantify removal and assess clinical benefits.

21 May 2025

Eating kombu daily enhances gut health and heart markers in men

A 12-week randomized trial found that daily intake of boiled kombu (Laminaria japonica) powder reduced body fat and raised adiponectin in Japanese men, while improving blood pressure and gut microbiota in both sexes. No significant effects were seen in women for body fat reduction or adiponectin.

20 May 2025

Study shows any exercise can benefit older adults' health

Physical activity helps protect older adults against disease. A new study reveals that the health benefits also apply to those who exercise less than the recommended amount.

20 May 2025

Lipid accumulation levels reveal hidden osteoporosis risk

Researchers investigate the use of lipid accumulation products as a predictor of osteoporosis.

14 May 2025

High fructose diets impair brain function and appetite control, study shows

Review highlights how excessive fructose intake disrupts brain energy balance, appetite regulation, and cognitive function. Processed sources, such as sugary drinks, may overwhelm metabolic pathways and induce neuroinflammation, particularly during adolescence.

30 Apr 2025

Curcumin shows promise for treating obesity, inflammation, and neurodegenerative diseases

Researchers explore the medicinal role of curcumin in the treatment and prevention of neuroinflammation and metabolic disorders.

30 Apr 2025

Disrupted body clocks raise risk of early death, study finds

A large cohort study from China and the U.S. shows that Circadian Syndrome (CircS)—a cluster of metabolic and behavioral disruptions—is linked to higher all-cause and cause-specific mortality. The risk increases with the number of CircS components, especially among adults aged 40–60.

29 Apr 2025

Gut bacteria and metabolites reveal depression-linked patterns in older adults

A cross-sectional study of 400 older adults with metabolic syndrome reveals that individuals with depression have distinct gut microbiota and metabolite profiles. Eight bacterial genera and 15 fecal metabolites were significantly associated with depression, suggesting a gut-brain axis link.

29 Apr 2025

Pecans lower cholesterol and improve diet quality in at-risk adults, study finds

Substituting 57 grams of pecans for usual snacks over 12 weeks improved lipid profiles and diet quality but did not affect vascular function in adults at cardiometabolic risk. A modest weight gain was also observed.

29 Apr 2025

Metabolic syndrome in midlife linked to higher dementia risk

Having a larger waistline, high blood pressure and other risk factors that make up metabolic syndrome is associated with an increased risk of young-onset dementia, according to a study published on April 23, 2025, online in Neurology®, the medical journal of the American Academy of Neurology.

23 Apr 2025

Interferon regulatory factor 8 identified as key driver of liver fat buildup in NAFLD

Non-alcoholic fatty liver disease (NAFLD) is a hepatic metabolic syndrome resulting from lipid metabolic imbalance. Interferon regulatory factor 8 (IRF8) is well known for its roles in immune cell differentiation and tumor pathogenesis; however, its role in regulating glucose homeostasis and lipid metabolism remains unclear.

22 Apr 2025

New $15 million study aims to understand cardiovascular and kidney disease risk factors in women

Research teams from Augusta University, Massachusetts General Hospital and The Ohio State University will lead a $15 million project dedicated to studying the various ways that risk factors for cardiovascular and kidney diseases impact women.

22 Apr 2025

Metabolic syndrome found to increase risk of breast cancer recurrence and death

New research to be presented at this year's European Congress on Obesity (ECO 2025, Malaga, Spain, 11-14 May) and published in The Journal of Internal Medicine shows that, in survivors of breast cancer, having an unhealthy metabolic profile or so called 'metabolic syndrome' increases the risk of breast cancer recurrence by 69%, and subsequent breast cancer mortality by 83%.

16 Apr 2025