Metabolism News and Research

Latest Metabolism News and Research

Dileucine more effective than leucine in stimulating muscle-building in humans

In a randomized control study of 10 healthy young men, researchers compared how consuming the single amino acid leucine or its two-molecule equivalent, dileucine, influenced muscle-building and breakdown.

9 Aug 2021

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Last year, University of Alabama at Birmingham researchers reported that reductive stress - an imbalance in the normal oxidation/reduction homeostasis - caused pathological changes associated with heart failure in a mouse model.

6 Aug 2021

Research suggests potential new treatment strategy for phenylketonuria

Researchers at The University of Texas MD Anderson Cancer Center have discovered a critical new factor in regulating phenylalanine metabolism and, therefore, in preventing the inherited metabolic disorder phenylketonuria (PKU).

5 Aug 2021

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Researchers remain perplexed as to why some patients infected with SARS-CoV-2, the virus responsible for COVID-19, remain asymptomatic while other patients develop severe disease symptoms.

5 Aug 2021

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Researchers in Singapore have discovered that brain cells cannot maintain the cholesterol-rich myelin sheath that protects and insulates neurons in the absence of a protein called TDP-43.

4 Aug 2021

Open-access database could speed up repurposing of old drugs as new treatments

Researchers have created a new open-access database of information on drug candidates and how they are metabolized by the body, which could help speed up the repurposing of old drugs as new treatments.

3 Aug 2021

New breath test to tailor the dosage of drugs administered to epileptic patients

Epilepsy affects some 50 million people worldwide and pharmaceutical treatment of the disease is a tightrope walk, as the dose must be tailored precisely to the individual patient: "Slightly too little and it isn't effective. Slightly too much and it becomes toxic," explains Professor Pablo Sinues.

3 Aug 2021

Pfizer moves towards an oral anti-COVID-19 therapy

Researchers in the United States have described a novel antiviral agent against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) currently being evaluated in clinical trials as a treatment for coronavirus disease 2019 (COVID-19).

2 Aug 2021

Study reveals effective strategy to extend the benefit of immunotherapy for prostate cancer

It's a scientific riddle tangled up in a complex web. How do you turn an immune cold cancer into one that responds to immunotherapy?

2 Aug 2021

Scientists develop a potent peptide inhibitor of SARS-CoV-2 in vitro

In a recently published article in the journal Drugs in R&D, scientists have described the development and validation of a 13-amino acid peptide inhibitor of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 Aug 2021

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Researchers at the University of Virginia School of Medicine have overturned conventional wisdom on the workings of vital hormone receptors within cells, a finding that could boost drug development for diabetes and related metabolic disorders, cancer and other diseases.

31 Jul 2021

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

Mitofusin 2 is a key protein in the regulation of the physiology of mitochondria ─cellular organelles that produce energy─ involved in several neurodegenerative and cardiovascular diseases, as well as in cancer.

30 Jul 2021

Vitamin D supplements are not effective for easing painful IBS symptoms, study reveals

Vitamin D supplements are not an effective treatment for easing painful symptoms of Irritable Bowel Syndrome (IBS), a new study from the University of Sheffield reveals.

29 Jul 2021

Two new proteins identified as therapeutic targets for preventing NAFLD and associated liver cancer

An international study led by the Lipids&Liver research team at the UPV/EHU-University of the Basque Country, the results of which have recently been published in the prestigious journal Cancer Research, has demonstrated that inhibiting either of the proteins E2F1 or E2F2 in the liver protects against the development of obesity-driven nonalcoholic fatty liver disease and its progression to cancer.

29 Jul 2021

Non-invasive imaging method can predict the efficiency of cardiomyocyte differentiation

Stem cell research holds great potential for regenerative therapies and treatments to combat cardiovascular disease, which is responsible for over 30% of all deaths worldwide.

28 Jul 2021

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Researchers from the Institute of Process Engineering of the Chinese Academy of Sciences, Beijing Chaoyang Hospital and the University of Queensland have developed a new formulation based on regulatory T-cell exosomes (rEXS) to deliver vascular endothelial growth factor (VEGF) antibodies for choroidal neovascularization therapy.

26 Jul 2021

Metrion Biosciences appoints Nick Foster as Chief Commercial Officer and Head of Global Business Development

Metrion today announced the appointment of Nick Foster as Chief Commercial Officer and Head of Global Business Development.

26 Jul 2021

3D imaging reveals degeneration of liver sympathetic nerves in nonalcoholic fatty liver disease

With the application of a novel three-dimensional imaging technology, researchers at Karolinska Institutet in Sweden have discovered that one portion of the autonomic nervous system in the liver undergoes severe degeneration in non-alcoholic fatty liver disease.

22 Jul 2021

Researchers develop a cell culture test to detect substances that harm the placenta and embryo

Researchers at ETH Zurich have developed a cell culture test to detect substances that are directly or indirectly harmful to embryos. Based on an existing test used for developing new drugs and chemicals, the augmented version is designed to help reduce the number of animal experiments.

22 Jul 2021

Researchers identify immune protein linked to rare neurodegenerative disease

UT Southwestern researchers have identified an immune protein tied to the rare neurodegenerative condition known as Niemann-Pick disease type C.

21 Jul 2021

Metabolism News and Research

Latest Metabolism News and Research

Dileucine more effective than leucine in stimulating muscle-building in humans

Research reveals a microRNA network as putative mediators of myocardial reductive stress

Research suggests potential new treatment strategy for phenylketonuria

Specific and sensitive biomarker in the blood predicts symptomatic COVID-19 infection

Restoring cholesterol levels could be a new therapeutic approach for diseases linked to TDP-43 protein

Open-access database could speed up repurposing of old drugs as new treatments

New breath test to tailor the dosage of drugs administered to epileptic patients

Pfizer moves towards an oral anti-COVID-19 therapy

Study reveals effective strategy to extend the benefit of immunotherapy for prostate cancer

Scientists develop a potent peptide inhibitor of SARS-CoV-2 in vitro

UVA researchers overturn conventional wisdom on action of key hormone receptors within cells

Study provides new understanding on function of mitofusin 2 in cellular energy metabolism

Vitamin D supplements are not effective for easing painful IBS symptoms, study reveals

Two new proteins identified as therapeutic targets for preventing NAFLD and associated liver cancer

Non-invasive imaging method can predict the efficiency of cardiomyocyte differentiation

Researchers develop new exosome formulation to deliver VEGF antibodies for synergistic therapy

Metrion Biosciences appoints Nick Foster as Chief Commercial Officer and Head of Global Business Development

3D imaging reveals degeneration of liver sympathetic nerves in nonalcoholic fatty liver disease

Researchers develop a cell culture test to detect substances that harm the placenta and embryo

Researchers identify immune protein linked to rare neurodegenerative disease

Redefining control and consistency in anaerobic microbiome workflows

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting