Metabolism News and Research

Latest Metabolism News and Research

Antibiotic exposure and its priming effect on disease-causing bacteria

Antibiotics save lives -- but using them also helps antibiotic-resistant strains evolve and spread. Each year, antibiotic-resistant bacteria infect some 2.8 million people in the United States, killing more than 35,000, according to the Centers for Disease Control and Prevention.

27 Apr 2020

Prolonged corticosteroid treatment increases adrenal gland inflammation

New research by academics at the University of Bristol has found evidence that prolonged treatment of synthetic corticosteroid drugs increases adrenal gland inflammation in response to bacterial infection, an effect that in the long-term can damage adrenal function.

27 Apr 2020

Gut microbiota could predict severity of COVID-19

The COVID-19 pandemic is spreading to every corner of the world. But not everyone is falling sick at the same rate. A new study published on the preprint server medRxiv in April 2020 suggests that the composition of the gut microbiome could partially explain the difference in susceptibility. This adds a new dimension to what is currently known about the disease.

27 Apr 2020

Investigational drug may hold benefit for patients with lung and ovarian cancers

In a first-time disclosure of IPN60090, a small-molecule inhibitor of the metabolic enzyme glutaminase (GLS1), researchers from The University of Texas MD Anderson Cancer Center's Therapeutics Discovery division and Ipsen Biopharmaceuticals reported the preclinical discovery and early-stage clinical development of this novel drug. IPN60090, now under investigation in a Phase I trial, may hold benefit for certain patients with lung and ovarian cancers.

27 Apr 2020

Brain insulin sensitivity linked to body weight and fat distribution

Just where fat is deposited in the body and to what degree a person may benefit from a lifestyle intervention depends, among other things, on how sensitive the brain is to insulin.

24 Apr 2020

Study can serve as basis for developing new approaches for obesity, diabetes

In the 21st century, the search for methods of treating noncommunicable diseases, such as obesity, metabolic syndrome, and diabetes are among the top priorities.

24 Apr 2020

A protein discovery could pave way to better treatments for obesity

A USC-led international team of scientists has found the precise shape of a key player in human metabolism, which could lead the way to better treatments for obesity and other metabolic disease.

23 Apr 2020

Higher levels of specific gene can indicate better prognosis in prostate cancer

The most common form of cancer in older men is prostate cancer. In many cases the tumor grows slowly and can be treated effectively, but it is sometimes more aggressive and becomes terminal.

23 Apr 2020

Hyperferritinemia associated with increased illness severity in COVID-19

Yehuda Shoenfeld is the world's leading expert in the research, treatment and prevention of autoimmune diseases.

22 Apr 2020

AMPK activation by anti-diabetes drug promotes survival of dormant breast cancer cells

Most breast cancers utilize the female hormone estrogen to grow, so drug-induced estrogen deprivation is used as a treatment in many patients. However, cancer will recur in one-third of these patients.

22 Apr 2020

Specialized nerve cells promote the consumption of high-fat food

High-calorie, energy-dense foods are constantly available in our modern society. Researchers at the Max Planck Institute for Metabolism Research in Cologne have discovered that a group of nerve cells in the brains of mice promotes the consumption of high-fat food.

22 Apr 2020

Study reveals potential therapeutic target for treating cocaine addiction

A new study explains how cocaine modifies functions in the brain revealing a potential target for therapies aimed at treating cocaine addiction.

22 Apr 2020

Sweat-powered electronic skin can be used for multiple purposes

One of the ways we experience the world around us is through our skin. From sensing temperature and pressure to pleasure or pain, the many nerve endings in our skin tell us a great deal.

22 Apr 2020

Slightly elevated blood glucose levels can trigger major changes in insulin-producing cells

In diabetes, tiny clusters of insulin-producing "beta cells" in the pancreas don't produce enough of the hormone to keep people healthy, and their blood glucose levels climb.

22 Apr 2020

Age-related DNA modifications linked with susceptibility to eye disease

National Eye Institute researchers profiling epigenomic changes in light-sensing mouse photoreceptors have a clearer picture of how age-related eye diseases may be linked to age-related changes in the regulation of gene expression.

21 Apr 2020

Study finds how metabolism regulates sleep in worms

Can staying up late make you fat? A growing body of research has suggested that poor sleep quality is linked to an increased risk of obesity by deregulating appetite, which in turn leads to more calorie consumption.

21 Apr 2020

NEI researchers link age-related DNA modifications to susceptibility to eye disease

Researchers profiling epigenomic changes in mouse photoreceptors suggest that age-related eye diseases may be linked to gene expression.

21 Apr 2020

Do ACE inhibitors increase SARS-CoV-2 binding to ACE2?

The COVID-19 pandemic has forced clinicians and academicians to intensive research to find evidence for many conventional therapies. A new round-up editorial published in the journal Cardiovascular Research in April 2020 summarizes the current clinical grounds for and against the use of the commonly used angiotensin axis inhibitors in patients with COVID-19.

20 Apr 2020

Diverse diet as effective as sports nutrition products for female athletes, study finds

The edge. Every athlete, from the professional to the weekend warrior, strives to obtain that ever-elusive element that leads to victory - sometimes sparing no expense to get there.

18 Apr 2020

Scents regulate lipid metabolism without changing eating habits

Dr. Ayse Sena Mutlu, a postdoctoral fellow at Baylor's Huffington Center On Aging, had an intriguing question. Is it possible to change the body's fat storage without changing eating habits?

16 Apr 2020