Metabolism News and Research

Latest Metabolism News and Research

Maternal consumption of low-calorie sweeteners alters metabolism, gut microbiota in offspring

Many people turn to artificial or so-called natural sweeteners to cut calories and lose weight. A new study led by Dr. Raylene Reimer, PhD, published in the high-impact journal Gut discovered that the consumption of low-calorie sweeteners while pregnant increased body fat in their offspring and disrupted their gut microbiota - the trillions of bacteria and other microorganisms that inhabit the intestinal tract and affect our health and risk of numerous diseases.

29 Jan 2020

Researchers develop first non-invasive way to monitor oxygen in tumors during radiation therapy

Oxygen in cancer tumors is known to be a major factor that helps radiation therapy be successful. Hypoxia, or starvation of oxygen, in solid tumors is also thought to be an important factor in resistance to therapy.

29 Jan 2020

Research uncovers disease-aggravating mutation in mouse model of GRACILE syndrome

The new mitochondrial DNA (mtDNA) variant drastically speeds up the disease progression in a mouse model of GRACILE syndrome. This discovery provides a new tool for studies of mitochondrial diseases.

29 Jan 2020

Analysis of Postmortem Microbes using Gas Chromatography

In this interview, Katelynn Perrault, from Chaminade University of Honolulu talks to News-Medical and Life Sciences about her research into using Multidimensional Gas Chromatography to achieve odor profiling of postmortem microbes.

From Pittcon 29 Jan 2020

Specific gut microbes have the capacity to affect normal skeletal growth and maturation

Microbes are often seen as pathogens that cause disease, but the picture is actually more complex than that limited view.

28 Jan 2020

Research provides insights about sex- and gender-specific aspects of medicine

At present, a focus on males in basic research and clinical trials means that models of disease are also based on men. Symptoms and disease progression in male patients are therefore considered the standard, while disease manifestations that are usually observed in women are judged "atypical".

28 Jan 2020

Low-protein diet throughout pregnancy and lactation may increase risk of liver damage

A study in rats examines a pathway through which protein deficiency during pregnancy leads to fat accumulation in the liver and increased risk of liver damage.

28 Jan 2020

Human organ chips for better drug development

The process of developing new drugs is both difficult and costly. It is estimated that of all the drug candidates which start out on their testing journey, less than 14% actually make it to the clinical scene and receive approval by the US Food and Drug Administration (FDA).

27 Jan 2020

Study suggests prenatal origin for ‘young’ Parkinson’s disease

A new study published in the journal Nature Medicine on January 2020 suggests that Parkinson’s disease developing before the age of 50 years could be due to an abnormality in certain brain cells that remains dormant until the age of onset of the disease. It also indicates the potential usefulness of a specific drug to prevent this by correcting the brain cell disorder.

27 Jan 2020

Preterm survival rate up by 25 percent thanks to the quality improvement program

Preterm birth occurs before 37 weeks of gestation and has been tied to many complications in the infant. In Canada, the rate of survival of very preterm infants born between 28 to 32 weeks, improved by 25 percent, thanks to the national Evidence-based Practice for Improving Quality (EPIQ) program in neonatal intensive care units (NICUs) across the country.

27 Jan 2020

Keto diet produces health benefits in the short term, Yale study finds

A ketogenic diet -- which provides 99% of calories from fat and only 1% from carbohydrates -- produces health benefits in the short term, but negative effects after about a week, Yale researchers found in a study of mice.

27 Jan 2020

Study traces the molecular roots of hypertrophic cardiomyopathy

The heart's ability to beat normally over a lifetime is predicated on the synchronized work of proteins embedded in the cells of the heart muscle.

27 Jan 2020

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

A new study analyzes 30 years of patient data and details the clinical course of 184 individuals with genetically diverse forms of Maple Syrup Urine Disease (MSUD), which is among the most volatile and dangerous inherited metabolic disorders.

24 Jan 2020

Study sheds light on how norepinephrine release influences the fear-memory formation

Researchers at RIKEN Center for Brain Science have visualized the dynamic processes involving norepinephrine that influence different types of fear-memory formation in a living mouse model.

24 Jan 2020

Researchers observe fast and slow molecular pathways that support memory function

A sustained state of vigilance will generate a different type of memory than a momentary startle, and these differences are linked to distinct signaling molecules in the brains of mice.

24 Jan 2020

Scientists visualize diabetes-related proteins at high resolution

Scientists have examined a key receptor for the first time at high resolution - broadening understanding of how it might function, and opening the door to future improvements in treating conditions such as type 2 diabetes.

24 Jan 2020

Study uncovers large, giant viruses that belong to NCLDV supergroup

While the microbes in a single drop of water could outnumber a small city's population, the number of viruses in the same drop - the vast majority not harmful to humans could be even larger.

24 Jan 2020

Study reveals presence of functional extracellular mitochondria in the bloodstream

Mitochondria are organelles that are found in the eukaryotic cells. A place of cellular respiration, they are the cells' "batteries" and play a major role in energy metabolism and intercellular communication.

23 Jan 2020

Discovery could lead to early identification of children at high risk of future type 2 diabetes

Researchers at the University of Plymouth and Nestlé have revealed new insights into the factors that predispose children to developing type 2 diabetes in adult life.

23 Jan 2020

Combination of two immune defense strategies could afford alternative approach to treating sepsis

The human immune system uses two pre-programmed strategies to tackle infection. One is fever, a resistance mechanism that tries to eliminate a pathogen by raising the body's temperature.

23 Jan 2020

Metabolism News and Research

Latest Metabolism News and Research

Maternal consumption of low-calorie sweeteners alters metabolism, gut microbiota in offspring

Researchers develop first non-invasive way to monitor oxygen in tumors during radiation therapy

Research uncovers disease-aggravating mutation in mouse model of GRACILE syndrome

Analysis of Postmortem Microbes using Gas Chromatography

Specific gut microbes have the capacity to affect normal skeletal growth and maturation

Research provides insights about sex- and gender-specific aspects of medicine

Low-protein diet throughout pregnancy and lactation may increase risk of liver damage

Human organ chips for better drug development

Study suggests prenatal origin for ‘young’ Parkinson’s disease

Preterm survival rate up by 25 percent thanks to the quality improvement program

Keto diet produces health benefits in the short term, Yale study finds

Study traces the molecular roots of hypertrophic cardiomyopathy

30-year study of MSUD highlights critical need for more effective disease-modifying therapies

Study sheds light on how norepinephrine release influences the fear-memory formation

Researchers observe fast and slow molecular pathways that support memory function

Scientists visualize diabetes-related proteins at high resolution

Study uncovers large, giant viruses that belong to NCLDV supergroup

Study reveals presence of functional extracellular mitochondria in the bloodstream

Discovery could lead to early identification of children at high risk of future type 2 diabetes

Combination of two immune defense strategies could afford alternative approach to treating sepsis

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy