Metabolism News and Research

Latest Metabolism News and Research

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

For years scientists and dieticians have argued over the health benefits of dietary fat. Research published this week, however, shows that piggybacking onto natural fat absorption pathways can dramatically enhance the utility of some drugs.

10 Aug 2016

SBP researchers discover potential drug target for treatment of type 2 diabetes

Researchers at the Sanford Burnham Prebys Medical Discovery Institute (SBP) have identified a new potential target for drugs to prevent type 2 diabetes. A paper published today in the Journal of Clinical Investigation shows that blocking a cellular glucose sensor in muscle improves insulin responsiveness.

10 Aug 2016

Rare genetic variations linked to severe porphyria

An international research team has linked rare variations in a cell membrane protein to the wide variation in symptom severity that is a hallmark of porphyria, a rare disorder that often affects the skin, liver and nervous system.

10 Aug 2016

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

Researchers have uncovered how genes identified from genome-wide association studies (GWAS) affect high-density lipoprotein cholesterol (HDL-C), a biomarker of cardiovascular disease, after comparing several animal models with human patient data.

10 Aug 2016

MedDiet improves memory and slows cognitive decline, study shows

Eating a Mediterranean diet can slow down cognitive decline.The Mediterranean diet can improve your mind, as well your heart, shows a study published in the open-access journal

9 Aug 2016

Researchers shed new light on roots of dystonia

Researchers at VIB-KU Leuven have managed to get a clearer view on the roots of dystonia, a neurological disorder that causes involuntary twisting movements.

9 Aug 2016

Wistar scientists discover novel mechanism that helps tumors adapt to hypoxia

One of the many reasons tumors are so difficult to treat is that they are able to adapt whenever they are exposed to unfavorable conditions.

9 Aug 2016

Researchers develop new non-invasive technique to prevent burn scars

A group of researchers from Tel Aviv University and Harvard University has devised a new non-invasive method to prevent burn scarring caused by the proliferation of collagen cells.

9 Aug 2016

Scientists make major advance in understanding how stem cells become specialized

Scientists at Sanford Burnham Prebys Medical Discovery Institute have made a major advance in understanding how the cells of an organism, which all contain the same genetic information, come to be so diverse.

5 Aug 2016

Soy isoflavones may help improve metabolic and cardiovascular health in women with PCOS

Women who have polycystic ovary syndrome (PCOS)—a common cause of female infertility—may be able to improve their metabolic and cardiovascular health by consuming soy isoflavones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Aug 2016

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

A combination of three medications—dapagliflozin, liraglutide and insulin—helped people with Type 1 diabetes improve blood sugar control and lose weight, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

5 Aug 2016

Women using contraception containing estrogen may have high vitamin D levels, study shows

Women risk having their vitamin D levels fall when they stop using birth control pills or other contraceptives containing estrogen, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism.

4 Aug 2016

Review provides new insights into diagnosis, treatment for PCOS

Polycystic ovary syndrome (PCOS) afflicts over 14 million women in the United States. The disorder increases the risk of endometrial cancer, heart disease, high blood pressure, type 2 diabetes, asthma, obesity, depression and anxiety, as well as infertility and a variety of reproductive disorders.

4 Aug 2016

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Mucous membrane pemphigoid is an autoimmune disease that causes inflammation and scarring in mucosal tissues. Affected individuals frequently exhibit scarring in the eye, which can lead to blindness in as many as 20% of patients.

4 Aug 2016

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Reprogramming of the molecular pathways underlying normal metabolism is essential for T cell infection-fighting function and for the immune system to form a "memory" of the microbes it has already encountered. But exactly how metabolism in exhausted T cells is maintained in chronic infections and cancer is a missing element in this line of research.

3 Aug 2016

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

The microenvironment that supports a cancerous tumor also starves the immune cells that the body sends in to destroy the cancer, University of Pittsburgh Cancer Institute scientists revealed in a discovery that holds the potential to significantly boost the performance of breakthrough immunotherapy drugs.

2 Aug 2016

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

Paternal intake of a high-fat diet (HFD) can cause genetic changes that lead to generational obesity and metabolic dysfunction—including body weight and fat mass increases and changes in blood pressure, triglyceride levels and fat metabolism—in mice, according to Japanese researchers at Okayama University.

2 Aug 2016

Metabolism News and Research

Latest Metabolism News and Research

New technology uses natural nano-scale lipid transport system to deliver drugs straight to bloodstream

SBP researchers discover potential drug target for treatment of type 2 diabetes

Rare genetic variations linked to severe porphyria

Researchers uncover how GWAS-implicated gene affects HDL-cholesterol levels

MedDiet improves memory and slows cognitive decline, study shows

Researchers shed new light on roots of dystonia

Wistar scientists discover novel mechanism that helps tumors adapt to hypoxia

Researchers develop new non-invasive technique to prevent burn scars

Scientists make major advance in understanding how stem cells become specialized

Soy isoflavones may help improve metabolic and cardiovascular health in women with PCOS

Triple therapy approach helps Type 1 diabetes patients improve blood sugar control, lose weight

Women using contraception containing estrogen may have high vitamin D levels, study shows

Review provides new insights into diagnosis, treatment for PCOS

Studies highlight key role for vitamin A metabolite retinoic acid in ocular fibrosis

Metabolic-checkpoint inhibitor combination approach may improve cancer therapies

Research finding opens door to potential clinical approaches that may boost body's ability to battle cancer

Paternal over-nutrition may lead to generational obesity and metabolic dysfunction

New framework may help health professionals better understand, manage complexities of obesity

Diet rich in saturated fat reduces person's cognitive function making it difficult to control eating habits

Study verifies human gene therapy in MPS I animal model

How microRNA is transforming science: From discovery to diagnostics

Advancing benzodiazepine detection

The Surgeon-Scientist Pioneering Regenerative Engineering