Metabolism News and Research

Latest Metabolism News and Research

New Clinical Practice Guideline for diagnosis, treatment of acromegaly

The Endocrine Society today issued a Clinical Practice Guideline (CPG) for the diagnosis and treatment of acromegaly, a rare condition caused by excess growth hormone in the blood.

31 Oct 2014

Moffitt researcher uncovers new approach to treat cancer

The scientific community has made significant strides in recent years in identifying important genetic contributors to malignancy and developing therapeutic agents that target altered genes and proteins. A recent approach to treat cancer called synthetic lethality takes advantage of genetic alterations in cancer cells that make them more susceptible to certain drugs.

31 Oct 2014

Changes in cell metabolism slow growth of colorectal cancer

Cancer is an unwanted experiment in progress. As the disease advances, tumor cells accumulate mutations, eventually arriving at ones that give them the insidious power to grow uncontrollably and spread. Distinguishing drivers of cancer from benign mutations open opportunities for developing targeted cancer therapies.

30 Oct 2014

Researchers explore association between vitamin A and neonatal health

The impact vitamin A has on newborns is virtually unknown, but Penn State nutrition researchers have published two papers that may provide a framework for future investigations of the vitamin and neonatal health.

30 Oct 2014

UAlberta researchers discover link between pulmonary hypertension, diabetes and cancer

A UAlberta team has discovered that a protein that plays a critical role in metabolism, the process by which the cell generates energy from foods, is important for the development of pulmonary hypertension, a deadly disease.

30 Oct 2014

Rare neuroendocrine tumours may be misdiagnosed as Cushing’s disease

Ectopic tumours secreting corticotropin-releasing hormone and adrenocorticotropic hormone are very rare in children and can result in a misdiagnosis of Cushing’s disease, say researchers.

30 Oct 2014

Study on papillary thyroid carcinoma to be presented at 84th Annual Meeting of the ATA

The prevalence of papillary thyroid carcinoma (PTC), the most common type of thyroid cancer, is increasing rapidly. New research to determine the impact of radioactive iodine (RAI) therapy on survival in PTC, describing a novel blood test able to detect circulating BRAFV600E-positive tumor DNA, and identifying a long non-coding RNA specifically associated with the thyroid that is down-regulated in PTC compared to normal thyroid tissue in patient-derived clinical specimens and cell cultures will be featured in oral presentations delivered at the 84th Annual Meeting of the American Thyroid Association, October 29-November 2, 2014, in Coronado, California.

30 Oct 2014

Fewer women than men receive dialysis treatment for chronic kidney disease

Women with chronic kidney disease receive dialysis treatment far less often than men. However, women suffer more commonly than men from kidney disease. A publication by the MedUni Vienna and the Arbor Research Collaborative for Health, USA, has highlighted this difference based on international patient data.

29 Oct 2014

Game theory and the cancer ecosystem: an interview with Professor Pienta, Johns Hopkins

The classic description of game theory was described by the prisoner's dilemma, which is a situation in which two players have two options where the outcome depends on the simultaneous choice made by the other.

29 Oct 2014

CHOP, Temple University to jointly investigate new methods for eradicating HIV

The Children's Hospital of Philadelphia and Temple University have received a joint $4.3 million, four-year grant from the National Institute of Mental Health to investigate new methods to eradicate HIV that lurks in brain cells despite conventional antiviral treatments.

28 Oct 2014

Dietary cocoa flavanols can reverse age-related memory decline in healthy older adults

Dietary cocoa flavanols—naturally occurring bioactives found in cocoa—reversed age-related memory decline in healthy older adults, according to a study led by Columbia University Medical Center scientists.

27 Oct 2014

Early brain imaging studies may help prevent vascular diseases

Future prevention and treatment strategies for vascular diseases may lie in the evaluation of early brain imaging tests long before heart attacks or strokes occur, according to a systematic review conducted by a team of cardiologists, neuroscientists, and psychiatrists from Icahn School of Medicine at Mount Sinai and published in the October issue of JACC Cardiovascular Imaging.

27 Oct 2014

Research shows FGF21 hormone acts directly on brain to regulate obesity

A hormone seen as a popular target to develop weight-loss drugs works by directly targeting the brain and triggering previously unknown activity in the nervous system, UT Southwestern Medical Center obesity researchers have found.

24 Oct 2014

$Insulin resistance linked to treatment-refractory bipolar disorder$

Insulin resistance linked to treatment-refractory bipolar disorder

Patients with bipolar disorder who are insulin resistant are likely to also be refractory to mood-stabilising treatment, report researchers.

22 Oct 2014

Levodopa dose linked to malnutrition risk in Parkinson’s disease

The malnutrition often seen in patients with Parkinson’s disease could be partly an effect of levodopa medication, research suggests.

22 Oct 2014

Marital hostility, history of depression can increase obesity risk in adults

The double-whammy of marital hostility and a history of depression can increase the risk for obesity in adults by altering how the body processes high-fat foods, according to new research.

22 Oct 2014

Research: MHCI protein moonlights in nervous system to regulate synapses

When it comes to the brain, "more is better" seems like an obvious assumption. But in the case of synapses, which are the connections between brain cells, too many or too few can both disrupt brain function.

21 Oct 2014

Fatty fish intake appears to increase antidepressant response rates

Up to half of patients who suffer from depression (Major Depressive Disorder, or MDD) do not respond to treatment with SSRIs (Selective Serotonin Reuptake Inhibitors). Now a group of Dutch researchers have carried out a study which shows that increasing fatty fish intake appears to increase the response rate in patients who do not respond to antidepressants.

21 Oct 2014

UNMC researcher receives $3.3 million grant to study rare diseases that affect children

University of Nebraska Medical Center researcher, William Rizzo, M.D., has received a five-year, $3.3 million grant to study 10 rare diseases that affect children beginning in infancy or early childhood and throughout their life.

20 Oct 2014

Newborns of mothers who smoke during pregnancy have altered stress hormones, DNA

Researchers from The Miriam Hospital have studied the effects of smoking during pregnancy and its impact on the stress response in newborn babies. Their research indicates that newborns of mothers who smoke cigarettes during pregnancy show lower levels of stress hormones, lowered stress response, and alterations in DNA for a gene that regulates passage of stress hormones from mother to fetus.

20 Oct 2014