Metabolism News and Research

Latest Metabolism News and Research

Older mothers who exercise during pregnancy can reduce baby's risk of congenital heart defects

In people, a baby's risk of congenital heart defects is associated with the age of the mother. Risk goes up with increasing age. Newborn mice predisposed to heart defects because of genetic mutations show the same age association.

2 Apr 2015

CVD risk assessment still important in severely obese adolescents

Researchers report a dose–response relationship between body mass index and cardiovascular risk even in severely obese adolescents, making its assessment important to limit further disease progression.

1 Apr 2015

FGF21 protein can boost regenerative effects of human PPARα

Researchers at UC Davis have illuminated an important distinction between mice and humans: how human livers heal. The difference centers on a protein called PPARα, which activates liver regeneration. Normally, mouse PPARα is far more active and efficient than the human form, allowing mice to quickly regenerate damaged livers.

1 Apr 2015

IDT supports unique bioengineering public outreach program

To help the general public understand how bioengineering is changing the world for the better, Integrated DNA Technologies (IDT) is supporting a unique public outreach program led by expert plant synthetic biologists at Revolution Bioengineering.

From Integrated DNA Technologies 31 Mar 2015

PAION initiates Remimazolam Phase 3 trial in patients undergoing colonoscopy

PAION, Inc., a wholly owned subsidiary of PAION AG, today announced the initiation of a U.S. Phase 3 clinical trial of Remimazolam, an ultra-short-acting sedative/anesthetic, for procedural sedation in patients undergoing colonoscopy.

31 Mar 2015

Researchers use fast-scanning PAM to see blood oxygenation, other functions inside living brain

Researchers studying cancer and other invasive diseases rely on high-resolution imaging to see tumors and other activity deep within the body's tissues. Using a new high-speed, high-resolution imaging method, Lihong Wang, PhD, and his team at Washington University in St. Louis were able to see blood flow, blood oxygenation, oxygen metabolism and other functions inside a living mouse brain at faster rates than ever before.

31 Mar 2015

Useful tips for physicians to help patients make the right choice on statin drugs

Cholesterol-lowering statins have transformed the treatment of heart disease. But while the decision to use the drugs in patients with a history of heart attacks and strokes is mostly clear-cut, that choice can be a far trickier proposition for the tens of millions of Americans with high cholesterol but no overt disease.

31 Mar 2015

CNIO researchers describe presence of MDH2 gene mutations in hereditary neuroendocrine tumors

Researchers in the Hereditary Endocrine Cancer Group of the Spanish National Cancer Research Centre -- led by Alberto Cascón and Mercedes Robledo -- have described the presence of mutations in the MDH2 gene, in a family with very rare neuroendocrine tumours associated with a high hereditary component: pheochromocytomas and paragangliomas that affect the suprarenal and parathyroid glands (groups of chromaffin cells in the central nervous system), respectively.

30 Mar 2015

Investigational S-equol nutritional supplement may alleviate certain menopause symptoms

The investigational S-equol nutritional supplement may be a viable agent to alleviate certain menopause symptoms, such as hot flashes, according to a new peer-reviewed article in the March Journal of Women's Health.

30 Mar 2015

DaVita Kidney Care celebrates its dietitians and social workers

DaVita Kidney Care, a division of DaVita HealthCare Partners Inc. and a leading provider of kidney care services, is celebrating its more than 3,600 dietitians and social workers during March for their distinctive and important roles in patient care.

30 Mar 2015

Brown fat tissue communicates with the brain through sensory nerves

Brown fat tissue, the body's "good fat," communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity, such as how much fat we have and how much fat we've lost, according to researchers at Georgia State University.

30 Mar 2015

APrON study: Pregnant and lactating women not meeting recommended intake of omega-3

Alberta Pregnancy Outcomes and Nutrition (APrON) is a birth cohort involving over two thousand women and their infants from Calgary and Edmonton that was funded by Alberta Innovates Health Solutions and includes researchers at the University of Alberta and the University of Calgary.

30 Mar 2015

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

According to our understanding, mitochondria undergo cycles of fusion-fission, i.e. they divide within the constraints of a cell and, upon cell division, each of the two daughter cells gets its ‘share’ of mitochondria.

29 Mar 2015

Griffith study explores how beer can be manipulated to improve its rehydration potential

It was only recently that Griffith University research showed that it’s possible to improve the hydrating effects of beer without killing off its taste.

27 Mar 2015

Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

A Task Force convened by the American Thyroid Association released updated guidelines for the diagnosis and treatment of medullary thyroid carcinoma (MTC). The current document is the first revision of the original guidelines published in 2009.

26 Mar 2015

Helsinn, Mundipharma sign distribution and license agreement for anamorelin

Helsinn, a Swiss Group focused on building quality cancer care, and Mundipharma, today announce that they have entered into a distribution and license agreement for the exclusive rights to anamorelin in China, Hong Kong and Macao.

26 Mar 2015

Top scientists to attend 3rd annual Helmholtz-Nature Medicine Diabetes Conference

As a unique scientific panel it brings together top scientists as well as promising young researchers from different disciplines in a personal and selected ambience.

26 Mar 2015

Metabolic imbalance can trigger respiratory diseases in early childhood

An imbalance in our metabolism can trigger inflammatory processes in the body and activate the immune system. In a recent study, published in the Journal of Allergy and Clinical Immunology, UFZ researchers have been able to show that this applies even to newborns and children under one year of age, and is correlated with the development of respiratory diseases in early childhood.

26 Mar 2015

Transition announces positive results from ELND005 AME and renal clearance studies

Transition Therapeutics Inc. today announced results from two phase 1 clinical studies of neuropsychiatric drug candidate ELND005. These studies, an absorption-metabolism-excretion ("AME") study and a renal clearance study, are specialized clinical pharmacology trials that are required by the United States Food and Drug Administration for the approval of most drugs in development.

26 Mar 2015

TSRI scientists identify enzyme that maintains healthy periods of inactivity in HSCs to prevent anemia

Stem cells can generate any type of cell in the body, but they are inactive most of the time—and for good reason. When stem cells become too active and divide too often, they risk acquiring cell damage and mutations. In the case of blood stem cells (also called hematopoietic stem cells or HSCs), this can lead to blood cancers, a loss of blood cells and an impaired ability to fight disease.

26 Mar 2015

Metabolism News and Research

Latest Metabolism News and Research

Older mothers who exercise during pregnancy can reduce baby's risk of congenital heart defects

CVD risk assessment still important in severely obese adolescents

FGF21 protein can boost regenerative effects of human PPARα

IDT supports unique bioengineering public outreach program

PAION initiates Remimazolam Phase 3 trial in patients undergoing colonoscopy

Researchers use fast-scanning PAM to see blood oxygenation, other functions inside living brain

Useful tips for physicians to help patients make the right choice on statin drugs

CNIO researchers describe presence of MDH2 gene mutations in hereditary neuroendocrine tumors

Investigational S-equol nutritional supplement may alleviate certain menopause symptoms

DaVita Kidney Care celebrates its dietitians and social workers

Brown fat tissue communicates with the brain through sensory nerves

APrON study: Pregnant and lactating women not meeting recommended intake of omega-3

Mitochondrial DNA movement: an interview with Professor Jiri Neuzil, Griffith University

Griffith study explores how beer can be manipulated to improve its rehydration potential

Updated guidelines for diagnosis, treatment of medullary thyroid carcinoma released

Helsinn, Mundipharma sign distribution and license agreement for anamorelin

Top scientists to attend 3rd annual Helmholtz-Nature Medicine Diabetes Conference

Metabolic imbalance can trigger respiratory diseases in early childhood

Transition announces positive results from ELND005 AME and renal clearance studies

TSRI scientists identify enzyme that maintains healthy periods of inactivity in HSCs to prevent anemia

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Digital pathology and the PathoVerse: A conversation with Dr. Singh