Metabolism News and Research

Latest Metabolism News and Research

Roche proposes to acquire Illumina for $44.50 per share

Roche announced today that it is proposing to acquire all outstanding shares of Illumina, Inc. for $44.50 per share in cash, or an aggregate of approximately $5.7 billion on a fully diluted basis.

From Roche Sequencing and Life Science 24 Jan 2012

Cholesterol receptor allows entry of HCV virus into human liver cells

A molecule embedded in the membrane of human liver cells that aids in cholesterol absorption also allows the entry of hepatitis C virus, the first step in hepatitis C infection, according to research at the University of Illinois at Chicago College of Medicine.

24 Jan 2012

Brown fat burns in the cold and could hold key to burning excess fat: Study

Brown fat is something that occurs more in thin people than fat, younger people than older and young women than men. It is brown in color and a new study finds that one form of it, which is turned on in cold climates can burn calories from elsewhere in the body to keep the body warm. Another new study finds that a second form of brown fat can be created from ordinary white fat by exercise.

24 Jan 2012

Five scientists named recipients of Damon Runyon-Rachleff Innovation Award for cancer research

The Damon Runyon Cancer Research Foundation announced that five scientists with novel approaches to fighting cancer have been named 2012 recipients of the Damon Runyon-Rachleff Innovation Award.

24 Jan 2012

Study takes a closer look at high fructose corn syrup and table sugar

With growing concern that excessive levels of fructose may pose a great health risk - causing high blood pressure, kidney disease and diabetes - researchers at the University of Colorado School of Medicine, along with their colleagues at the University of Florida, set out to see if two common sweeteners in western diets differ in their effects on the body in the first few hours after ingestion.

24 Jan 2012

CQA derivatives in mate tea kill human colon cancer cells

Could preventing colon cancer be as simple as developing a taste for yerba mate tea? In a recent University of Illinois study, scientists showed that human colon cancer cells die when they are exposed to the approximate number of bioactive compounds present in one cup of this brew, which has long been consumed in South America for its medicinal properties.

24 Jan 2012

Scientists use metabolomics to discover DMS linked with neuropathic pain

Millions of people worldwide suffer from a type of chronic pain called neuropathic pain, which is triggered by nerve damage. Precisely how this pain persists has been a mystery, and current treatments are largely ineffective. But a team led by scientists from The Scripps Research Institute, using a new approach known as metabolomics, has now discovered a major clue: dimethylsphingosine (DMS), a small-molecule byproduct of cellular membranes in the nervous system.

23 Jan 2012

SSRI use raises risk of fall among elderly with dementia: Study

A new study reveals that nursing home residents with dementia who use selective serotonin reuptake inhibitors (SSRIs) have an increased risk of having a fall that causes injury compared with those who do not use SSRIs. Additionally those using average doses have 3 times the risk compared with nonusers, the authors, led by Carolyn S. Sterke, from Erasmus University Medical Center, Rotterdam, the Netherlands, report. Authors write, “Even at low doses, SSRIs are associated with increased risk of an injurious fall in nursing home residents with dementia.”

22 Jan 2012

Exercise fails to improve glucose metabolism in autophagy-deficient mice

The health benefits of exercise on blood sugar metabolism may come from the body's ability to devour itself, UT Southwestern Medical Center researchers report in the journal Nature.

21 Jan 2012

Red wine could play a role in lowering risk of breast cancer

Aromatase inhibitors (AIs) prevent the conversion of androgens to estrogens, and could play a role in the development of breast cancer. This study of 36 pre-menopausal women consisted of a cross-over intervention trial to determine if there were differences between red wine and white wine in their effects on AIs.

20 Jan 2012

WSU professors receive NSF grant to develop math model of liver metabolism

Predicting problems in one of the body's most complex organs soon may become easier because of work being done by Wayne State University researchers.

20 Jan 2012

External stimuli control hormonal regulation of our eating behavior

Max Planck researchers have proven something scientifically for the first time that laypeople have always known: the mere sight of delicious food stimulates the appetite. A study on healthy young men has documented that the amount of the neurosecretory protein hormone ghrelin in the blood increases as a result of visual stimulation through images of food.

20 Jan 2012

Insufficient sleep increases risk of becoming overweight

New research from Uppsala University, Sweden, shows that a specific brain region that contributes to a person's appetite sensation is more activated in response to food images after one night of sleep loss than after one night of normal sleep. Poor sleep habits can therefore affect people's risk of becoming overweight in the long run. The findings are published in the Journal of Clinical Endocrinology & Metabolism.

19 Jan 2012

Gastric bypass superior to lap banding finds study

A new study evaluates the best option in terms of weight loss surgery for those who need it. Researchers found gastric bypass patients lose more weight than gastric banding patients and keep it off longer. Even though banding is a simpler operation, nearly half of those patients were still obese after six years.

17 Jan 2012

Scientists discover novel mechanism to prevent cell death of nerve cells

Oxygen and glucose are the food of our brain. If they are absent, such as during a stroke, nerve cells die. An international research team at Charité - Universitätsmedizin Berlin, Germany, and McMaster University, Canada, has discovered a novel mechanism to prevent this cell death. The results of the study have now been published in the journal Proceedings of the National Academy of Sciences of the USA.

16 Jan 2012

Hormone that burns energy discovered

Boston scientists have found a hormone that is secreted by muscles during exercise and boosts the amount of energy the body burns. This hormone – irisin – could be the first step in development of new drugs for obesity, diabetes, and other diseases feel researchers. A Boston startup company, Ember Therapeutics, has already licensed the technology and is working to develop a form of the hormone that could be used as a drug that would mimic some of the benefits of exercise.

16 Jan 2012

Agilux implements Thermo Watson LIMS for bioanalytical services

Agilux Laboratories, a provider of pharmaceutical and biotech services, today announced that it has completed the validation and implementation of the Thermo Watson Laboratory Information Management System (LIMS) for the company's bioanalytical services.

13 Jan 2012

NimbleGen Sequence Capture 385K array identifies gene mutations linked with hereditary hearing loss

Hereditary hearing loss is the most common sensory disorder in humans. A German research team led by Ingo Kurth from the Institute of Human Genetics at the University Hospital Jena, Germany, used a number of different methods, including Roche's NimbleGen Custom Sequence Capture 385K array to identify the gene mutated in the disease locus of the X-chromosome of a Spanish family with hereditary hearing loss.

13 Jan 2012

Gut bacteria may determine outcome of heart attack

New research published online in the FASEB Journal suggests that the types and levels of bacteria in the intestines may be used to predict a person's likelihood of having a heart attack, and that manipulating these organisms may help reduce heart attack risk.

13 Jan 2012

TAMEST honors UT Southwestern scientist with Edith and Peter O'Donnell Award

Dr. Philipp Scherer, director of the Touchstone Center for Diabetes Research at UT Southwestern Medical Center, was recognized today as a rising star in Texas research by The Academy of Medicine, Engineering and Science of Texas.

13 Jan 2012