Metabolism News and Research

Latest Metabolism News and Research

New targeting approach to develop an active site-directed, drug-like PTP1B inhibitor

The work of a team of scientists at Cold Spring Harbor Laboratory (CSHL) led by Professor Nicholas Tonks FRS, suggests a way to overcome one of the major technical obstacles preventing a leading therapeutic target for diabetes and obesity from being addressed successfully by novel drugs.

30 Sep 2011

Estradiol plays an important role in several metabolic diseases

Hormone researchers at the University of Houston (UH) have their sights set on providing long-term treatment options for diabetes, obesity and cardiovascular diseases by better understanding estradiol, the most potent naturally occurring estrogen.

30 Sep 2011

Kimmel Cancer Center at Jefferson celebrates two decades of caring and collaboration to beat cancer

From October forward, the Kimmel Cancer Center at Jefferson (KCC), a National Cancer Institute-designated cancer center, is celebrating 20 years of service to the community and the groundbreaking cancer research from the scientists and physicians who've provided an invaluable contribution to medical science and healthcare.

30 Sep 2011

Study provides insight into earliest stages of some cancers

A novel technique that enables scientists to measure and document tumor-inducing changes in DNA is providing new insight into the earliest events involved in the formation of leukemias, lymphomas and sarcomas, and could potentially lead to the discovery of ways to stop those events.

30 Sep 2011

Oral steroid users twice as likely to have severe vitamin D deficiency

People taking oral steroids are twice as likely as the general population to have severe vitamin D deficiency, according to a study of more than 31,000 children and adults by scientists at Albert Einstein College of Medicine of Yeshiva University.

30 Sep 2011

Good quality sleep is essential for overall health

Sleep plays a critical role in immune function, metabolism, memory, learning, growth, stress reduction and other vital functions. So getting the right amount of good quality sleep is as essential for overall health as good nutrition and regular exercise.

30 Sep 2011

Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

A pathway activated in cancer plays an unexpected key role in metabolic diseases like type 2 diabetes, according to a study by researchers at Children's Hospital Boston. Evidence that the Lin28/let-7 pathway influences the cellular response to glucose provides a unifying theme to perplexing data that associates human genetic variation with diabetes risk.

30 Sep 2011

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

Intensive control of blood sugar levels beyond standard targets provides no additional protection against cognitive decline in older people with diabetes than standard treatment, according to a national study coordinated by researchers at Wake Forest Baptist Medical Center.

29 Sep 2011

FOX06 protein contributes to liver overproduction of glucose in diabetes

Researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine have identified a powerful molecular pathway that regulates the liver's management of insulin and new glucose production, which could lead to new therapies for diabetes.

29 Sep 2011

Roche to sponsor 3rd Annual World MRSA Day

As part of its ongoing work in the prevention and control of serious infections in healthcare settings, Roche announced today its sponsorship of the 3rd Annual World MRSA Day.

From Roche Sequencing and Life Science 29 Sep 2011

NIH-funded project to study risk factors for alcoholism in Native Americans

Scripps Research Institute Professor Cindy Ehlers has been awarded a prestigious $3.6 million MERIT Award grant by the National Institutes of Health (NIH) to study the risk factors for alcoholism in Native Americans.

28 Sep 2011

Takeda, AACE partner to launch Diabetes Navigator website

The American Association of Clinical Endocrinologists (AACE) and Takeda Pharmaceuticals North America Inc. (Takeda) have partnered to launch the Diabetes Navigator, a compendium capturing a selection of useful and reliable type 2 diabetes information available online for patients and caregivers.

28 Sep 2011

Liver transplantation candidates without HCC derive greater survival benefit from LDLT

New research shows liver transplantation candidates without hepatocellular carcinoma (HCC) derive a greater survival benefit from a living donor liver transplant (LDLT) than waiting for a deceased donor liver transplant.

28 Sep 2011

Tips for health-conscious college students

If you polled students at any college or university, chances are one of their top complaints would be connected to diet. Everyone's heard of the "Freshman 15," and even when students are trying to eat well, it can be a challenge when time-intensive studies—and a thriving social life—translate into less-than-ideal food choices.

28 Sep 2011

Asians struggling with alcoholism may benefit from naltrexone

New UCLA psychology research indicates that Asians who are struggling with alcoholism may benefit especially from naltrexone, one of three medications approved by the U.S. Food and Drug Administration for the treatment of alcoholism.

28 Sep 2011

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

A study by scientists at the University of California, San Diego and UC Irvine has identified an enzyme called a proteasome phosphatase that appears to regulate removal of damaged proteins from a cell. The understanding of how this process works could have important implications for numerous diseases, including cancer and Parkinson's disease.

28 Sep 2011

Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that it has initiated dosing in its Phase I clinical trial with ALN-PCS, an RNAi therapeutic targeting proprotein convertase subtilisin/kexin type 9, or PCSK9, for the treatment of severe hypercholesterolemia.

27 Sep 2011

New insights into actions of NSAIDs

Ibuprofen, naproxen, and related non-steroidal anti-inflammatory drugs (NSAIDs) - the subjects of years of study - still have some secrets to reveal about how they work.

26 Sep 2011

Scientists reveal link between lipid cell dysfunction and metabolic diseases

By measuring the radioactive isotope carbon-14, scientists at Karolinska Institutet have revealed an association between lipid cell dysfunction and diseases such as obesity, diabetes and blood lipid disorders.

26 Sep 2011

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

A Phase III study of Afinitor (everolimus) tablets in patients with non-cancerous kidney tumors, or angiomyolipomas, associated with tuberous sclerosis complex (TSC) met its primary endpoint of best overall angiomyolipoma response rate, which includes reduction in kidney tumor size and absence of new tumors.

26 Sep 2011

Metabolism News and Research

Latest Metabolism News and Research

New targeting approach to develop an active site-directed, drug-like PTP1B inhibitor

Estradiol plays an important role in several metabolic diseases

Kimmel Cancer Center at Jefferson celebrates two decades of caring and collaboration to beat cancer

Study provides insight into earliest stages of some cancers

Oral steroid users twice as likely to have severe vitamin D deficiency

Good quality sleep is essential for overall health

Lin28/let-7 pathway plays an unexpected key role in type 2 diabetes

Intensive blood glucose control therapy provides no added benefit against cognitive decline in older diabetics

FOX06 protein contributes to liver overproduction of glucose in diabetes

Roche to sponsor 3rd Annual World MRSA Day

NIH-funded project to study risk factors for alcoholism in Native Americans

Takeda, AACE partner to launch Diabetes Navigator website

Liver transplantation candidates without HCC derive greater survival benefit from LDLT

Tips for health-conscious college students

Asians struggling with alcoholism may benefit from naltrexone

Scientists identify proteasome phosphatase that appears to regulate removal of damaged proteins

Alnylam commences ALN-PCS Phase I trial in severe hypercholesterolemia

New insights into actions of NSAIDs

Scientists reveal link between lipid cell dysfunction and metabolic diseases

Afinitor Phase III study on angiomyolipomas associated with TSC meets primary endpoint

Pharmaceutical Manufacturing - Industry Focus eBook eBook

Leveraging the Radian ASAP in standard casework

A journey through science, software, and innovation: Insights from the Bruker software team

CellVoyant's AI-Powered Vision for the Future of Cell Therapy