Metabolism News and Research

Latest Metabolism News and Research

Methane in breath linked to obesity

New Cedars-Sinai research shows obese patients who test positive for methane on their breath have a significantly higher body mass index (BMI) than their peers.

7 May 2010

Imprinted genes may be the root cause of gender specific diseases, says study

Pregnancy places competing demands on a mother's physiology: Her body wants to produce a strong healthy baby but not at the expense of her own health. Some of the genes that she passes on to her child therefore try to protect her own body from excessive demands from her child.

7 May 2010

FDA assigns BYDUREON new PDUFA action date of October 22, 2010

Amylin Pharmaceuticals, Inc., Eli Lilly and Company and Alkermes, Inc. today announced that the U.S. Food and Drug Administration (FDA) has classified the BYDUREON™ (exenatide for extended-release injectable suspension) complete response as a Class 2 resubmission and assigned a new Prescription Drug User Fee Act (PDUFA) action date of October 22, 2010.

6 May 2010

New study shows single night of partial sleep deprivation can induce insulin resistance

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism, just one night of short sleep duration can induce insulin resistance, a component of type 2 diabetes.

6 May 2010

Dark chocolate may protect brain after stroke by increasing cellular signals: Researchers

Researchers at Johns Hopkins have discovered that a compound in dark chocolate may protect the brain after a stroke by increasing cellular signals already known to shield nerve cells from damage.

6 May 2010

Proper nutrition during multi-day stage races may prevent harmful changes in bone turnover: Study

The recent start of the North American cycling season marks the beginning of a physically demanding time for elite and professional bicycle racers who participate in multi-day stage races. Previous research has found that competitive cyclists have significantly lower bone mineral density than other endurance athletes, making them more susceptible to fractures.

6 May 2010

Positive results from Phase IIa clinical study of LIPO-102

Lithera, Inc. today announced positive results from a Phase IIa clinical study of LIPO-102, its novel injectable combination of salmeterol xinafoate and fluticasone propionate for selective, non-ablative fat reduction. LIPO-102 was well-tolerated when administered weekly for 8 weeks into the subcutaneous abdominal fat of healthy subjects.

6 May 2010

Single night of partial sleep deprivation induces insulin resistance in healthy people

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism (JCEM), just one night of short sleep duration can induce insulin resistance, a component of type 2 diabetes.

5 May 2010

Study shows training in rhythmic gymnastics improves bone health in adolescent girls

According to a new study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism, long-term elite rhythmic gymnastics exerts positive effects on volumetric bone density and bone geometry in adolescent girls.

5 May 2010

Decreasing radiotherapy doses given to 'cold spots' can help reduce side-effects

Fine-tuning radiotherapy to take into account which parts of a patient's tumor are growing fastest could improve control of cancer while subjecting patients to lower doses of radiation, Dutch researchers reported today at the 2nd European Lung Cancer Conference.

5 May 2010

Diets rich in whole grain reduce risk of obesity and other diseases related to metabolic syndrome

Evidence from observational studies indicates that diets rich in whole grain reduce risk of obesity and other diseases related to the metabolic syndrome e.g. type 2 diabetes and cardio-vascular disease. The mechanisms involved are only partially elucidated. Work within HEALTHGRAIN has revealed novel insights regarding some potential mechanisms.

5 May 2010

New treatments for intestinal failure, other intestinal absorption disorders

New treatments for intestinal failure and other intestinal absorption disorders are a step closer to the patients who need them after a discovery in Kelly Tappenden's University of Illinois laboratory.

5 May 2010

Australian researchers show positive effect of growth hormone on athletic performance

Australian researchers have published the results of a study, for the first time showing a positive effect of growth hormone on athletic performance.

5 May 2010

Animal study shows insulin prevents artery damage

Long suspected of worsening artery damage in patients with diabetes, insulin instead protects blood vessels, a new study by Joslin Diabetes Center scientists indicates.

5 May 2010

Mayo Clinic researchers identify genetic variants in serotonin genes that impact IBS

Most people associate serotonin with brain neurology, but over 95 percent of the body's serotonin occurs in the gastrointestinal tract, which has a complex neuronal circuit that has been called "the second brain" of the body.

5 May 2010

Roche announces Health Canada approval for ACTEMRA to treat RA

Roche today announced that Health Canada has approved ACTEMRA(TM) (tocilizumab) to treat patients with rheumatoid arthritis (RA), a chronic, progressive inflammatory disease of the joints and surrounding tissues that is associated with intense pain, irreversible joint destruction and systemic complications, such as fatigue and anemia.

4 May 2010

Synta Pharmaceuticals reports net loss of $9.3 million for first-quarter 2010

Synta Pharmaceuticals Corp., a biopharmaceutical company focused on discovering, developing, and commercializing small molecule drugs to treat severe medical conditions, today reported financial results for the quarter ended March 31, 2010.

4 May 2010

LA BioMed receives $1.5M in grant to study contraceptive for men

As the birth control pill marks its 50th birthday this month, Los Angeles Biomedical Research Institute announced today that it has received $1.5 million in grant funding to study a contraceptive for men that uses a combination of two hormonal gels applied to the skin of the arm and abdomen.

4 May 2010

Deficiency of frataxin protein causes Friedreich's ataxia

The defective gene responsible for Friedreich's ataxia was identified over 20 years ago, but so far our ideas of how this gene causes the disease have been merely speculative. It was assumed that, as a result of the mutation, the gene could no longer be transcribed because this stretch of DNA was inaccessible. FMI Group Leader Marc Bühler and his team have now carried out experiments demonstrating that this is not the case and revealing what actually happens in Friedreich's ataxia.

4 May 2010

Obese men more likely to have low testosterone than non-obese men: HIM study

Obesity, a condition linked to heart disease and diabetes, now appears to be associated with another health problem, but one that affects men only -- low testosterone levels.

4 May 2010

Metabolism News and Research

Latest Metabolism News and Research

Methane in breath linked to obesity

Imprinted genes may be the root cause of gender specific diseases, says study

FDA assigns BYDUREON new PDUFA action date of October 22, 2010

New study shows single night of partial sleep deprivation can induce insulin resistance

Dark chocolate may protect brain after stroke by increasing cellular signals: Researchers

Proper nutrition during multi-day stage races may prevent harmful changes in bone turnover: Study

Positive results from Phase IIa clinical study of LIPO-102

Single night of partial sleep deprivation induces insulin resistance in healthy people

Study shows training in rhythmic gymnastics improves bone health in adolescent girls

Decreasing radiotherapy doses given to 'cold spots' can help reduce side-effects

Diets rich in whole grain reduce risk of obesity and other diseases related to metabolic syndrome

New treatments for intestinal failure, other intestinal absorption disorders

Australian researchers show positive effect of growth hormone on athletic performance

Animal study shows insulin prevents artery damage

Mayo Clinic researchers identify genetic variants in serotonin genes that impact IBS

Roche announces Health Canada approval for ACTEMRA to treat RA

Synta Pharmaceuticals reports net loss of $9.3 million for first-quarter 2010

LA BioMed receives $1.5M in grant to study contraceptive for men

Deficiency of frataxin protein causes Friedreich's ataxia

Obese men more likely to have low testosterone than non-obese men: HIM study

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut