Metabolism News and Research

Latest Metabolism News and Research

Zengen announces positive results of treatment for vaginal yeast infection

Zengen Inc. announced today positive phase I/II results for its proprietary molecule CZEN-002 for the treatment of vulvovaginal candidiasis (VVC), commonly known as vaginal yeast infection.

25 May 2004

Data suggests potential target for Alzheimer's disease treatment

Researchers from Weill Cornell Medical College and Columbia University College of Physicians & Surgeons have discovered at least one way in which beta-amyloid, the protein that forms stubborn plaques in the brains of Alzheimer's disease patients, can kill nerve cells.

25 May 2004

Intensive exercising after menopause may reduce bone loss

Early postmenopausal women with osteoporosis who participate in an intense exercise program may experience reduced bone loss, reduced back pain, and lower cholesterol levels, according to an article in the May 24 issue of The Archives of Internal Medicine, one of the JAMA/Archives journals.

24 May 2004

Trial shows Daclizumab therapy improves multiple sclerosis outcome

A small clinical trial of patients with multiple sclerosis (MS) who did not respond to interferon alone found that adding the human antibody daclizumab improved patient outcome. Patients who received the combined therapy had a 78 percent reduction in new brain lesions and a 70 percent reduction in total lesions, along with other significant clinical improvements.

24 May 2004

Diabetes drug improves metabolic changes associated with HIV combination therapy

Use of an oral antidiabetes medication produced significant improvement in a group of patients with HIV lipodsytrophy, a syndrome involving the redistribution of fat and other metabolic changes in those receiving combination drug therapy for HIV infection.

20 May 2004

Protein that appears to play a key role in Alzheimer's disease

A protein that allows human cancer to resist multiple anticancer drugs also appears to play a key role in Alzheimer's disease, according to research conducted at Fox Chase Cancer Center. The protein, active in brain tissue, could be a target for new drugs to treat patients with Alzheimer's.

20 May 2004

Dietary supplement reduces body fat mass in overweight adults by as much as nine percent

A study to be published in the June issue of The American Journal of Clinical Nutrition concludes that the dietary supplement, conjugated linoleic acid (CLA), reduces body fat mass in overweight, but otherwise healthy, adults by as much as nine percent.

20 May 2004

Caffeinated beverages may benefit some people who are at high-risk for liver disease

According to new research presented today at Digestive Disease Week, drinking caffeinated beverages may benefit some people who are at high-risk for liver disease. Conversely, a study by researchers from India found that soda drinkers, who represent a huge percentage of the American population, may actually have an increased risk of developing esophageal cancer.

19 May 2004

Study finds greater weight loss among the low-carbohydrate dieters than high-carbohydrate dieters

Two randomized trials of low-fat versus low-carbohydrate weight loss diets, published in the May 18 issue of the Annals of Internal Medicine, found greater weight loss among the low-carbohydrate dieters at six months.

17 May 2004

First filing for zoledronic acid in metabolic bone disease

One 15-minute infusion of the intravenous bisphosphonate zolendronic acid more rapidly reduced the biochemical markers of bone turnover in patients with Paget's disease than was seen in a head-to-head comparison with the oral treatment risedronate (95% vs. 75% response rate).

17 May 2004

Glucose metabolism could be used to selectively destroy cancer cells

Scientists have known for decades that cancer cells consume more glucose than normal cells. A longstanding assumption that the excess glucose metabolism was needed to make energy has not been borne out by research studies.

15 May 2004

Vitamin discovery offers clues for cancer chemotherapy

NH-Dartmouth Medical School cancer researchers, in a fusion of biochemistry and genetics, have discovered a new vitamin in a molecular pathway central to such vital processes as gene regulation, metabolism and aging. And, they found that milk contains this nutrient.

15 May 2004

Estrogen therapy may help bone density, muscle mass, sexual function, memory, and psychological wellbeing in postmenopausal women

Research in monkeys suggests that long-term use of estrogen therapy may reduce levels of androgens – hormones involved in maintaining bone density, muscle mass, sexual function, memory, and psychological wellbeing in postmenopausal women.

14 May 2004

Compound found in the peels of citrus fruit can potentially lower cholesterol more effectively than prescription drugs

A compound found in the peels of citrus fruit has the potential to lower cholesterol more effectively than some prescription drugs, and without side effects, according to a study by U.S. and Canadian researchers.

11 May 2004

Small, frequent doses of caffeine best strategy for staying awake

Caffeine is the world's most widely-used stimulant yet, scientists still do not know exactly how it staves off sleep. Researchers at Brigham and Women's Hospital, Harvard Medical School and other institutions have now discovered that caffeine works by thwarting one of two interacting physiological systems that govern the human sleep-wake cycle.

11 May 2004

New patent has potential for the treatment of obesity

Two researchers have announced receipt of a patent on the use of MSH analogs--chemicals that regulate fat storage and metabolism in the body.

11 May 2004

Low fat/high carb eating plan is not bad for good cholesterol

A slight fall in blood levels of HDL (“good”) cholesterol in men due to a low-fat, high-carbohydrate eating plan may not be a problem, researchers reported today at the American Heart Association’s 5th Annual Conference on Arteriosclerosis, Thrombosis and Vascular Biology.

8 May 2004

International research team have decoded the genetic blueprint of the tularemia (rabbit fever) bacterium

Two teams of researchers, one based in the United States and the other in Europe, have decoded the genetic blueprint of the tularemia (rabbit fever) bacterium, a highly infectious human and animal pathogen.

6 May 2004

Study shows Chromium Picolinate and Biotin Combination significantly lowers coronary risk factors in people with Type 2 Diabetes

Results of a new double-blind, placebo-controlled, randomized clinical study show that daily nutritional supplementation with a combination of chromium picolinate and biotin (marketed as Diachromeä) significantly improved coronary risk factors in people with type 2 diabetes.

6 May 2004

New guidelines for using new antiepileptic drugs to treat epilepsy

The number of drugs available to treat epilepsy have more than doubled in the last decade. The American Academy of Neurology and the American Epilepsy Society have assembled the top experts in the field to evaluate the available data of 1,462 research articles in order to create a guideline for the treatment of epilepsy with the new antiepileptic drugs (AEDs).

6 May 2004

Metabolism News and Research

Latest Metabolism News and Research

Zengen announces positive results of treatment for vaginal yeast infection

Data suggests potential target for Alzheimer's disease treatment

Intensive exercising after menopause may reduce bone loss

Trial shows Daclizumab therapy improves multiple sclerosis outcome

Diabetes drug improves metabolic changes associated with HIV combination therapy

Protein that appears to play a key role in Alzheimer's disease

Dietary supplement reduces body fat mass in overweight adults by as much as nine percent

Caffeinated beverages may benefit some people who are at high-risk for liver disease

Study finds greater weight loss among the low-carbohydrate dieters than high-carbohydrate dieters

First filing for zoledronic acid in metabolic bone disease

Glucose metabolism could be used to selectively destroy cancer cells

Vitamin discovery offers clues for cancer chemotherapy

Estrogen therapy may help bone density, muscle mass, sexual function, memory, and psychological wellbeing in postmenopausal women

Compound found in the peels of citrus fruit can potentially lower cholesterol more effectively than prescription drugs

Small, frequent doses of caffeine best strategy for staying awake

New patent has potential for the treatment of obesity

Low fat/high carb eating plan is not bad for good cholesterol

International research team have decoded the genetic blueprint of the tularemia (rabbit fever) bacterium

Study shows Chromium Picolinate and Biotin Combination significantly lowers coronary risk factors in people with Type 2 Diabetes

New guidelines for using new antiepileptic drugs to treat epilepsy

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

Examining how pain could play a direct protective role in the gut