Metabolism News and Research

Latest Metabolism News and Research

GlaxoSmithKline to acquire Sirtris Pharmaceuticals

GlaxoSmithKline and Sirtris Pharmaceuticals Incorporated announced today that they have entered into a definitive agreement pursuant to which GlaxoSmithKline will acquire Sirtris Pharmaceuticals for approximately USD720 million (or approx. GBP362 million) through a cash tender offer of USD22.50 (or approx. GBP11.33) per share.

22 Apr 2008

Vitamin D protects women from breast cancer

The connection between vitamin D levels and certain forms of cancer has been suspected for some time but now German researchers have come up with clear proof of the link.

21 Apr 2008

Raptor Pharmaceuticals initiates phase IIa clinical study for Convivia

Raptor Pharmaceuticals Corp. has announced that its clinical development subsidiary, Bennu Pharmaceuticals Inc. , has initiated the Company's first clinical-stage program after dosing the first cohort in a Phase IIa study of oral 4-methylpyrazole ("4-MP") in subjects with ALDH2 deficiency, or ethanol intolerance, as the initial development stage of its Convivia program.

21 Apr 2008

Hypertension all about what you eat and drink

Scientific research on human metabolism based on people from around the world has revealed compounds in urine indicate surprising differences affecting blood pressure.

20 Apr 2008

Vitamin D and the risk of developing breast cancer

A connection between vitamin D level and the risk of developing breast cancer has been implicated for a long time, but its clinical relevance had not yet been proven.

18 Apr 2008

First functional insulin-binding protein in invertebrates

Insulin-like growth factor (IGF) signaling that helps to regulate mammals' growth, metabolism, reproduction and longevity is well documented. Now research published in the open access journal Journal of Biology describes the genetic identification of the first functional insulin-like growth factor binding protein (IGFBP) ortholog in invertebrates.

17 Apr 2008

Boys are twice as likely as girls in the U.S. and Asia to receive growth hormone

Boys are twice as likely as girls in the U.S. and Asia (mostly Japan) to receive recombinant human growth hormone (rhGH) for growth hormone deficiency, illnesses that affect height, and short stature of a non-medical nature.

17 Apr 2008

Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment

Aerobic exercise could give older adults a boost in brainpower, according to a recent review of studies from the Netherlands.

17 Apr 2008

Cancer prevention

Tapping into a growing body of knowledge about the origins and progression of cancer, researchers are now developing and testing new preventive therapies to stop it in its tracks.

15 Apr 2008

New hope for blood disorder anaemia

A new understanding of how red blood cell production is controlled could lead to improvements in the treatment of the blood disorder anaemia, according to West Australian medical researchers.

13 Apr 2008

What we eat and drink affects our risk of cancer

A healthy diet and lifestyle protect against a wide range of diseases, and new research presented at the American Association for Cancer Research 2008 Annual Meeting, April 12-16, shows that cancer is no exception.

13 Apr 2008

Iron deficiency cause

The discovery of a gene for a rare form of inherited iron deficiency may provide clues to iron deficiency in the general population – particularly iron deficiency that doesn't respond to iron supplements - and suggests a new treatment approach.

13 Apr 2008

Power of molecular imaging reveals secrets of the heart

The extraordinary action of a new cellular therapy came to light as a result of powerful PET and SPECT imaging in a recent study reported in the April issue of the Journal of Nuclear Medicine.

10 Apr 2008

Potential drug target identified for diabetes by studying novel gut-brain-liver circuit

Scientists at the Toronto General Hospital Research Institute have discovered a novel signaling pathway between three organs - the gut, the brain, and the liver - which lowers blood sugar when activated.

10 Apr 2008

Keeping fit delays biological aging by up to 12 years

Maintaining aerobic fitness through middle age and beyond can delay biological ageing by up to 12 years and prolong independence during old age, concludes an analysis published ahead of print in the British Journal of Sports Medicine.

10 Apr 2008

Conjugated linoleic acid side effects - hormone leptin helps protect

An oil made of natural fatty acids that is sometimes used as a weight-loss supplement may need to be paired with hormones or other substances to prevent health problems that can follow rapid weight loss, a new study suggests.

10 Apr 2008

Lower target levels for blood pressure, LDL-cholesterol may provide cardiovascular benefits

Patients with diabetes who reduced their blood pressure and LDL-cholesterol to below standard target levels had a greater decrease in carotid artery wall thickness, but did not have a significant difference in cardiovascular disease events than patients who had recommended blood pressure and LDL-cholesterol levels, according to a study in the April 9 issue of JAMA, the Journal of the American Medical Association.

9 Apr 2008

Gene oppositely controlled by dietary protein, sugar

Researchers have discovered a gene in flies whose activity rises and falls depending upon the amount of protein and sugar in the insects' diets.

9 Apr 2008

Discovery of a critical early player in the path that turns cells to fat

Given that obesity - defined as an excess amount of body fat relative to lean body mass - is a major health concern in the United States and an increasing problem in the developing world, such a fuller understanding of the molecular processes governing fat tissue formation could ultimately hold clinical importance, according to the researchers.

9 Apr 2008

Treatment with an anti-psychotic drug found to cause changes in metabolism earlier than expected

Schizophrenia is a complex type of psychotic mental illness characterized by thoughts that are uncoupled from reality.

8 Apr 2008

Metabolism News and Research

Latest Metabolism News and Research

GlaxoSmithKline to acquire Sirtris Pharmaceuticals

Vitamin D protects women from breast cancer

Raptor Pharmaceuticals initiates phase IIa clinical study for Convivia

Hypertension all about what you eat and drink

Vitamin D and the risk of developing breast cancer

First functional insulin-binding protein in invertebrates

Boys are twice as likely as girls in the U.S. and Asia to receive growth hormone

Physical activity and enhanced fitness to improve cognitive function in older people without known cognitive impairment

Cancer prevention

New hope for blood disorder anaemia

What we eat and drink affects our risk of cancer

Iron deficiency cause

Power of molecular imaging reveals secrets of the heart

Potential drug target identified for diabetes by studying novel gut-brain-liver circuit

Keeping fit delays biological aging by up to 12 years

Conjugated linoleic acid side effects - hormone leptin helps protect

Lower target levels for blood pressure, LDL-cholesterol may provide cardiovascular benefits

Gene oppositely controlled by dietary protein, sugar

Discovery of a critical early player in the path that turns cells to fat

Treatment with an anti-psychotic drug found to cause changes in metabolism earlier than expected

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics