Metabolism News and Research

Latest Metabolism News and Research

SIRT1 gene suppresses longevity

Researchers have determined that a gene present in mouse cells limits the number of times that a cell can divide. The gene is involved in a process, called senescence, which is thought to ensure that aging cells do not pass on harmful mutations.

20 Jul 2005

Insulin keeps fat in the liver under control

Insulin, a hormone long recognized as a generator of fat, also keeps fat in the liver under control, according to a new study in the July issue of Cell Metabolism.

19 Jul 2005

Variant of a common protein plays a primary role in Type 2 diabetes and obesity

Scientists in France and the United States report that a variant of a common protein plays a primary role in Type 2 diabetes and obesity, key features of the "insulin resistance syndrome" that affects more than 50 million people in this country and a similar number in Europe.

19 Jul 2005

Genome studies may help target new drugs to fight them

One parasite causes a deadly sleeping sickness in Africa. The second damages the internal organs of millions of Latin Americans. The third causes terrible lesions on the face or limbs of victims from Brazil to India.

18 Jul 2005

New molecular insights may one day lead to opportunities to stave off old age

Delving deep into the molecular subtleties of a strain of mice engineered to age rapidly, scientists have found that an accumulation of genetic mutations prompts a cascade of programmed cell death that seems to underpin the aging process.

18 Jul 2005

Scientists sequence the genomes of three species of parasites responsible for causing diseases that kill or cripple millions

Howard Hughes Medical Institute (HHMI) scientists who participated in the project say the sequencing of the genomes of the parasitic protozoa that cause Chagas disease, African sleeping sickness, and leishmaniasis, could significantly impact world health. Some of the genes discovered may prove to be good drug and vaccine targets.

17 Jul 2005

Individuals with inactive heterozygous ALDH2, a tendency to alcohol flushing have a greater susceptibility to hangovers

Alcohol consumption is an integral part of the Japanese business culture. Hangovers, however, can have substantial economic drawbacks.

17 Jul 2005

Growing body of evidence indicating that childhood obesity is linked to a lack of exercise

A study published by the medical journal The Lancet dealt another blow to the "food police" and the trial lawyers seeking to blame food for the nation's expanding waistline.

15 Jul 2005

New insights into brain cell metabolism from PET and MRI scans

By discovering a crucial piece of submicroscopic information about how the brain converts fuel into energy for neurons, Cornell University biophysicists have gleaned new insights into brain cell metabolism that will allow neurologists to better interpret data from such diagnostic tests as positron emission tomography (PET) scans and a specialized magnetic resonance imaging (MRI) test.

12 Jul 2005

Discovery of protein deficit that causes drug toxicity

Mayo Clinic researchers have discovered an inherited structural mechanism that can make drugs for some diseases toxic for some patients.

11 Jul 2005

Fat adults more likely to have increased insulin resistance, a risk marker for Type 2 diabetes

Adult lifestyle has more influence on your chances of developing diabetes than childhood experience, according to new research whose findings contradict previously-held beliefs.

6 Jul 2005

Viagra's non-blood pressure effect successfully mimics vasopressin action

Normally your kidneys filter about 50 gallons of blood a day, remove such waste as salts and minerals, and concentrate it into urine. When you exercise or don't take in water, your blood "thickens" and instead of removing water, the kidney reverses the process, pulls in water from the body that would normally go into the urine, and puts it into the blood, thus maintaining water balance.

29 Jun 2005

Exercise helps find genetic regions linked to prediabetes

People's bodies respond to exercise in different ways, and their genetic makeup is partly responsible.

28 Jun 2005

Pregnancy and birth factors may determine likelihood of polycystic ovarian syndrome

New research suggests that the way baby girls develop in the womb may affect whether or not they develop polycystic ovarian syndrome (PCOS) as adults and the severity of the symptoms if they do.

27 Jun 2005

Minimally invasive approach to removing diseased thyroids

An incision about half the length used for traditional surgery works just as well in removing diseased thyroids, researchers have found.

27 Jun 2005

Technique called phylogenetic footprinting reveals new gene regulation system

By comparing 140 sequenced bacterial genomes, researchers have uncovered a system for regulating genes essential to bacterial replication - and they did it solely by computer keystrokes and mouse clicks.

27 Jun 2005

A blood test for thyroid cancer can detect persistent or recurrent disease even before doctors can find any trace of a tumor

The study, by researchers at The Ohio State University Comprehensive Cancer Center – Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSU CCC – James), examined how well a test for thyroid cancer can predict whether the disease will recur.

27 Jun 2005

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Children with a particular variation in the CYT19 gene metabolize arsenic differently than adults with the same genetic variant, according to a new research report. The findings have important implications for the safety of drinking water worldwide and the use of arsenic as a cancer drug.

27 Jun 2005

Computer program that enhances the diagnostic accuracy of positron emission tomography (PET)

German scientists developed a computer program that enhances the diagnostic accuracy of positron emission tomography (PET) scans with Alzheimer's patients, opening the door for earlier treatment of this progressive brain disorder. Details of their findings were provided at the Society of Nuclear Medicine's 52nd Annual Meeting in Toronto.

20 Jun 2005

PET might be a promising tool for early prediction of response to chemotherapy for ovarian can

Noninvasive positron emission tomography (PET) imaging may allow earlier prediction of a patient's response to chemotherapy for ovarian cancer, according to research reported at the Society of Nuclear Medicine's 52nd Annual Meeting June 18–22 in Toronto.

20 Jun 2005

Metabolism News and Research

Latest Metabolism News and Research

SIRT1 gene suppresses longevity

Insulin keeps fat in the liver under control

Variant of a common protein plays a primary role in Type 2 diabetes and obesity

Genome studies may help target new drugs to fight them

New molecular insights may one day lead to opportunities to stave off old age

Scientists sequence the genomes of three species of parasites responsible for causing diseases that kill or cripple millions

Individuals with inactive heterozygous ALDH2, a tendency to alcohol flushing have a greater susceptibility to hangovers

Growing body of evidence indicating that childhood obesity is linked to a lack of exercise

New insights into brain cell metabolism from PET and MRI scans

Discovery of protein deficit that causes drug toxicity

Fat adults more likely to have increased insulin resistance, a risk marker for Type 2 diabetes

Viagra's non-blood pressure effect successfully mimics vasopressin action

Exercise helps find genetic regions linked to prediabetes

Pregnancy and birth factors may determine likelihood of polycystic ovarian syndrome

Minimally invasive approach to removing diseased thyroids

Technique called phylogenetic footprinting reveals new gene regulation system

A blood test for thyroid cancer can detect persistent or recurrent disease even before doctors can find any trace of a tumor

New research raises the possibility that the risk of developing arsenic-related disease is not the same for everybody

Computer program that enhances the diagnostic accuracy of positron emission tomography (PET)

PET might be a promising tool for early prediction of response to chemotherapy for ovarian can

Fluidics in Modern Healthcare & Medical Device Innovation

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

How does norepinephrine influence anxiety-related behaviours?