Osteoarthritis News and Research

Latest Osteoarthritis News and Research

Nuvo receives BfArM positive opinion for Pliaglis

Nuvo Research Inc., a specialty pharmaceutical company dedicated to building a portfolio of products for the topical treatment of pain and the development of its immune modulating drug candidate WF10, today announced that it has received notice of a positive opinion from the European Decentralized Procedure for the approval of Pliaglis from the German Federal Institute for Drugs and Medical Devices (BfArM), the reference member state.

7 May 2012

Unigene first quarter net loss decreases to $6.0 million

Unigene Laboratories, Inc., today announced financial results for the first quarter ended March 31, 2012.

7 May 2012

Array BioPharma third quarter revenue increases to $19.1M

Array BioPharma Inc. today reported financial results for the third quarter of fiscal 2012.

2 May 2012

DJOFL first quarter net sales increase 11.7% to $278.9 million

DJO Global, Inc., a leading global provider of medical device solutions for musculoskeletal health, vascular health and pain management, today announced financial results for its operating subsidiary, DJO Finance LLC, for the first quarter ended March 31, 2012.

2 May 2012

Enrollment complete in Zalicus Synavive Phase 2b clinical trial for rheumatoid arthritis

Zalicus Inc., a biopharmaceutical company that discovers and develops novel treatments for patients suffering from pain and immuno-inflammatory diseases, today announced it has completed enrollment with 292 patients enrolled in the SYNERGY trial, a Phase 2b clinical trial designed to evaluate the safety and efficacy of Synavive, a low-dose glucocorticoid with the potential for amplified immuno-inflammatory benefits, in patients with rheumatoid arthritis (RA).

30 Apr 2012

Anxiety more common than depression among people with arthritis

Researchers from the Centers for Disease Control and Prevention (CDC) found that one-third of U.S. adults with arthritis, 45 years and older, report having anxiety or depression. According to findings that appear today in Arthritis Care & Research, a journal published by Wiley-Blackwell on behalf of the American College of Rheumatology (ACR), anxiety is nearly twice as common as depression among people with arthritis, despite more clinical focus on the latter mental health condition.

30 Apr 2012

Gender differences in musculoskeletal health are not solely due to hormones

Osteoarthritis, osteoporosis, fractures, and spinal disorders are among the most common reasons for doctor visits. These conditions have more than one thing in common: they are all musculoskeletal problems and are more prevalent in women.

26 Apr 2012

Method to manufacture cartilage from human embryonic stem cells

BioTime, Inc. and its wholly owned subsidiary OrthoCyte Corporation reported today a means of manufacturing cartilage from human embryonic stem cells that is suited for industrial scale-up of a product for the treatment of osteoarthritis.

23 Apr 2012

Orthopaedic research studies in the Journal of Bone and Joint Surgery

Below are highlights of orthopaedic research studies appearing in the April 18th issue of the Journal of Bone and Joint Surgery (JBJS), as well as the issue's full Table of Contents.

21 Apr 2012

Positive results from CrystalGenomics’ CG100649 Phase 2b OA study

CrystalGenomics, Inc., a biopharmaceutical company headquartered in Korea, has just announced positive results from the Phase 2b osteoarthritis (OA) study of the CG100649, CrystalGenomics' next-generation NSAID candidate.

19 Apr 2012

Exactech selects MMI to evaluate novel cartilage repair treatment

Medical Metrics Inc, (MMI), an experienced provider of medical imaging core lab services for global clinical trials, has been selected by Exactech, Inc. to conduct an independent evaluation of medical images from the BiPhasic Cartilage Repair Implant (BiCRI) IDE Clinical Trial approved by the Taiwan FDA.

19 Apr 2012

Oral bacteria may cause problems in arthritis patients

The culprit behind a failed hip or knee replacements might be found in the mouth. DNA testing of bacteria from the fluid that lubricates hip and knee joints had bacteria with the same DNA as the plaque from patients with gum disease and in need of a joint replacement.

19 Apr 2012

Study explains why women are more prone to knee injuries than men

Women are more prone to knee injuries than men, and the findings of a new study suggest this may involve more than just differences in muscular and skeletal structure - it shows that males and females also differ in the way they transmit the nerve impulses that control muscle force.

18 Apr 2012

Decreasing GPA adherence among COX-2 users increases risk of upper GI complications

To relieve pain, arthritis sufferers are prescribed medications that may include non-steroidal anti-inflammatory drugs (NSAIDs) or cyclooxygenase-2 (COX-2) inhibitors, both of which can irritate the digestive tract. At times additional drugs are co-prescribed with NSAIDs or COX-2 inhibitors to prevent adverse gastrointestinal (GI) effects.

16 Apr 2012

QRxPharma completes MoxDuo CR Phase 1 studies on chronic pain

QRxPharma announced today successful completion of two Phase 1 studies in healthy volunteers for MoxDuo CR, a controlled-release Dual-Opioid utilising a 3:2 ratio of morphine and oxycodone.

11 Apr 2012

Cartilage quality can be assessed using diffusion weighted imaging

A team at the MedUni Vienna, headed by Sebastian Apprich of the University Department of Radiodiagnostics at the High-Field Magnetic Resonance Centre of Excellence, has now discovered in collaboration with the University Department of Orthopaedics that the quality of cartilage tissue can also be determined without an invasive procedure: with the assistance of diffusion weighted imaging in a 3-Tesla scanner cartilage quality can be assessed in a much less invasive way.

5 Apr 2012

Nektar commences dosing in NKTR-192 Phase 1 clinical study for treatment of acute pain

Nektar Therapeutics announced today that the first subjects were dosed last week in a Phase 1 clinical study to evaluate the pharmacokinetics and safety of NKTR-192, the company's novel short-acting mu-opioid analgesic candidate.

2 Apr 2012

New ACR guidelines recommend use of topical NSAIDs for older patients with knee OA

The American College of Rheumatology (ACR) Subcommittee on Osteoarthritis Guidelines has approved and issued several updates to clinical practice guidelines for the treatment of osteoarthritis (OA).

31 Mar 2012

IMS supports new guidance on glucocorticoid use

The International Osteoporosis Foundation, along with the European Society for Calcified Tissue, launched new guidance on glucocorticoid use at the European Congress on Osteoporosis and Osteoarthritis (which took place in Bordeaux from March 21 - 24, 2012). Given the special relevance to postmenopausal women, the International Menopause Society (IMS) is supporting the publication of the guidance.

31 Mar 2012

Rare total shoulder replacement performed using rotator cuff sparing approach

On Tuesday, March 6, 2012, Ryan Simovitch, M.D., Board Certified and fellowship trained orthopedic surgeon, performed one of the first successful total shoulder replacements with a rotator cuff sparing technique in South Florida. Jupiter Medical Center remains on the leading edge of orthopedics, offering orthopedic surgeons, state-of-the-art facilities, and comprehensive rehabilitation services to help patients return to an active and healthy lifestyle.

29 Mar 2012