Osteoarthritis

According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.

What is Osteoarthritis?

Osteoarthritis is a degenerative joint disease that involves the degradation of joints, articular cartilage, and subchondral bone as a result of mechanical stress.

Osteoarthritis Causes

Osteoarthritis Diagnosis

Osteoarthritis Treatments

Osteoarthritis Symptoms

Osteoarthritis Types

Living with Osteoarthritis

Causes of Hand Pain

Osteoarthritis and Diet

Osteoarthritis Triggers

Turmeric for Osteoarthritis

Osteoarthritis Complications

See more featured articles »

Should You Exercise With Osteoarthritis?

Easing Hand Pain in Osteoarthritis

Natural Ways to Ease Osteoarthritis Pain

Supplements for Osteoarthritis

Latest Osteoarthritis News and Research

The potential of grape consumption to modulate UV-induced skin erythema

A recent Antioxidants study evaluated the effect of grape consumption on reducing UV-induced skin erythema.

2 Dec 2022

The effects of mechanical forces on musculoskeletal cells and tissues

In this interview, Dr. Marina Danalache, Lab leader at the Laboratory of Cell Biology, Department of Orthopedic Surgery, University of Tübingen talks to News-Medical Life Sciences about the ongoing research on the effects of mechanical forces on musculoskeletal cells and tissues, as well as how these forces mediate homeostasis and drive pathophysiological processes.

From Bruker JPK Instruments AG 30 Nov 2022

Corticosteroid injections associated with progression of knee osteoarthritis

Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease.

29 Nov 2022

Anti-inflammatory pain relievers may worsen inflammation in osteoarthritis

Taking anti-inflammatory pain relievers like ibuprofen and naproxen for osteoarthritis may worsen inflammation in the knee joint over time, according to a new study being presented next week at the annual meeting of the Radiological Society of North America.

21 Nov 2022

Artificial neural network creates synthetic x-ray images to overcome regulatory limitations

Sharing medical data between laboratories and medical experts is important for medical research. However, data sharing is often sufficiently complex and sometimes even impossible due to the strict data regulatory legislation in Europe. Researchers at the University of Jyväskylä Digital Health Intelligence Laboratory addressed the problem and developed an artificial neural network that creates synthetic x-ray images that can fool even medical experts.

17 Nov 2022

Mast cells in synovial tissue may explain why women report worse osteoarthritis pain than men

Investigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have significantly increased levels of immune cells called mast cells in synovial tissue surrounding the knee joint than men.

14 Nov 2022

Obese patients undergoing knee replacement have higher risk of revision surgery, study finds

University of Queensland research has revealed Australians undergoing a knee replacement operation are at a higher risk of needing further surgery if they're obese.

14 Nov 2022

Study assesses musculoskeletal health needs of underserved patients

To improve the health of a community, the first step is to identify its most pressing needs. To that end, in 2022 Hospital for Special Surgery (HSS) implemented a community-based participatory research (CBPR) approach to assess musculoskeletal health needs, identify health disparities and support the development of initiatives to address unmet needs.

14 Nov 2022

Genicular nerve blocks provide short term pain relief for patients with knee osteoarthritis

Results from a recent clinical trial published by Wiley in Arthritis & Rheumatology demonstrate that patients with knee osteoarthritis experience short term pain relief from genicular nerve blocks-;or locally injected anesthetics that block nerves around the knee joint.

13 Nov 2022

Centuries-old mobility aids may be replaced by wearable exoskeletons

Exoskeletons -- motorized mechanical devices attached to an individual’s body to assist movement -- have been a popular feature in science fiction movies from Robocop to Iron Man as a means to give someone superhuman skills.

9 Nov 2022

Rheumatoid arthritis patients taking opioids have twice the risk of venous thromboembolism

New research presented this week at ACR Convergence 2022, the American College of Rheumatology's annual meeting, found that adult RA patients starting opioids had twice the risk of venous thromboembolism (VTE) compared to patients starting nonsteroidal anti-inflammatory drugs (NSAIDs).

8 Nov 2022

UQ spin-off company to develop precision painkillers for treating debilitating conditions

Precision painkillers that are more accurate and less harmful to the liver are set to be developed by a University of Queensland spin-off company -; potentially changing the lives of millions of people.

3 Nov 2022

Dietary components do not have impact on RMD outcomes

In 2022, EULAR - the European Alliance of Rheumatology Associations - published new recommendations regarding lifestyle behaviors and work participation to prevent progression of rheumatic and musculoskeletal diseases (RMDs).

1 Nov 2022

Scientists use systems biology approach to identify molecular players in rheumatoid arthritis

Using a novel systems biology approach, scientists at University of California San Diego School of Medicine have further parsed the cellular players and roles involved in rheumatoid arthritis (RA), a complex disease that affects more than one million Americans in ways that have defied development of uniform treatments.

24 Oct 2022

EULAR points-to-consider offers support to improve healthy work participation of people with RMDs

Across Europe, people with RMDs are less able to work than people in the general population. One of the most common reasons is that people with RMDs often have pain caused by their disease.

20 Oct 2022

Study finds a possible new target to fight osteoarthritis

Wear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis.

14 Oct 2022

Total body PET/CT scans can effectively visualize systemic joint involvement in patients with arthritis

Total body PET/CT scans can successfully visualize systemic joint involvement in patients with autoimmune arthritis, according to new first-in-human research published in the October issue of The Journal of Nuclear Medicine.

14 Oct 2022

BMI: The mismeasure of weight and the mistreatment of obesity

People who seek medical treatment for obesity or an eating disorder do so with the hope their health plan will pay for part of it. But whether it's covered often comes down to a measure invented almost 200 years ago by a Belgian mathematician as part of his quest to use statistics to define the "average man."

12 Oct 2022

Study reveals immune characteristics of long-COVID

Researchers perform antibody profiling against SARS-CoV-2, several endemic pathogens, as well as vaccine antigens among rheumatic disease patients.

2 Oct 2022

Patients with late-stage knee OA incur high costs for nonoperative treatments before total knee arthroplasty

In the year before total knee arthroplasty (TKA), patients incur considerable costs for nonoperative treatments and other procedures for osteoarthritis (OA) – raising questions about the value of those procedures, reports a study in The Journal of Bone & Joint Surgery.

22 Sep 2022