Osteoarthritis

According to the Arthritis Foundation, 66 million (nearly one in three adults) suffer from chronic joint pain and 21 million Americans suffer from osteoarthritis (OA), the most common form of arthritis, which is characterized by a breakdown of the cartilage and a deterioration of the fluid in a joint. The symptoms of osteoarthritis include pain, from moderate to severe, and stiffness. Most people who have osteoarthritis are older than age 45, and women are more commonly affected than men.

What is Osteoarthritis?

Osteoarthritis is a degenerative joint disease that involves the degradation of joints, articular cartilage, and subchondral bone as a result of mechanical stress.

Osteoarthritis Symptoms

Easing Hand Pain in Osteoarthritis

Osteoarthritis Causes

Osteoarthritis Diagnosis

Osteoarthritis Treatments

Osteoarthritis Complications

Living with Osteoarthritis

Natural Ways to Ease Osteoarthritis Pain

Osteoarthritis Triggers

Should You Exercise With Osteoarthritis?

Osteoarthritis and Diet

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Osteoarthritis Types

Causes of Hand Pain

Supplements for Osteoarthritis

Turmeric for Osteoarthritis

Latest Osteoarthritis News and Research

Researchers develop novel engineered extracellular matrix to improve cartilage repair

Recently, a research team from Chongqing Medical University, led by Prof. Wei Huang, Dr. Wei Bao, and Dr. Yiting Lei, has successfully developed a novel engineered extracellular matrix (eECM) to address the challenge of cartilage repair.

11 Jul 2025

Biological age of the brain emerges as a powerful predictor of longevity

The candles on your birthday cake don't tell the whole story. As anyone who ever attended a high-school reunion can tell you, some people age faster than others.

10 Jul 2025

Artificial intelligence tracks aging and damaged cells through high resolution imaging

A combination of high-resolution imaging and machine learning, also known as artificial intelligence (AI), can track cells damaged from injury, aging, or disease, and that no longer grow and reproduce normally, a new study shows.

8 Jul 2025

Breakthrough dual-drug hydrogel promotes cartilage repair in osteoarthritis

A research team from Northwest University, China, has developed a breakthrough nano-composite hydrogel system to address the dual challenges of inflammation and cartilage damage in osteoarthritis (OA), a leading cause of joint disability worldwide.

3 Jul 2025

New protein target offers hope for chronic inflammation treatment

Chronic inflammation occurs when the immune system is stuck in attack-mode, sending cell after cell to defend and repair the body for months or even years.

2 Jul 2025

Danish trial reveals how structured exercise and guidance affect life with chronic conditions

A large multicenter trial found that a 12-week personalized exercise therapy and self-management support program produced a small but statistically significant improvement in health-related quality of life for adults with multimorbidity. The intervention was safe, but its clinical relevance remains uncertain, as only self-rated health showed a significant benefit over usual care.

1 Jul 2025

HIV treatment linked to risk of early knee osteoarthritis

Acquired immune deficiency syndrome, or AIDS, caused by the human immunodeficiency virus (HIV), weakens the body's immune system and can be life-threatening if left untreated.

1 Jul 2025

Cagrilintide and semaglutide together drive record weight loss in global trial

A 68-week phase 3 trial found that coadministered cagrilintide and semaglutide led to significant and clinically meaningful weight loss in adults with obesity but no diabetes. The combination outperformed either drug alone and improved multiple cardiometabolic health markers.

23 Jun 2025

New meta-analysis highlights effective non-drug therapies for knee osteoarthritis

Knee braces, water therapy and exercise are the most promising non-drug therapies for treating knee osteoarthritis, according to a new meta-analysis publishing June 18, 2025 in the open-access journal PLOS One by Yuan Luo of the First People's Hospital of Neijiang, China.

19 Jun 2025

Osteoarthritis treatment in practice falls short of EULAR guidelines

Osteoarthritis is a leading cause of chronic pain, often affecting physical function, daily activities, and quality of life.

14 Jun 2025

Exercise therapy shows long-term benefits for people with rheumatic diseases

Regular physical activity is increasingly promoted for people with rheumatic and musculoskeletal diseases (RMD) as well as the general population.

13 Jun 2025

Tufts researchers design new generation of weight loss medications

Weight loss drugs like Ozempic and Wegovy are used by over 15 million adults in the U.S., or 4.5% of the population. Despite their effectiveness, they have drawbacks.

11 Jun 2025

Spatial transcriptomics could transform musculoskeletal research

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context.

9 Jun 2025

New VR system transforms hand rehabilitation with load free design

In a significant advancement for hand rehabilitation, researchers from Zhengzhou University have introduced a non-hand-worn, load-free VR hand rehabilitation system that could boost therapy development for patients recovering from conditions like stroke and osteoarthritis.

29 May 2025

Breakthrough study finds genes behind calcium pyrophosphate deposition disease

In a first-of-its-kind genome-wide association study (GWAS) researchers have discovered two genes, RNF144B and ENPP1, that cause calcium pyrophosphate deposition (CPPD) disease in Americans of European and African descent.

28 May 2025

Lipid accumulation levels reveal hidden osteoporosis risk

Researchers investigate the use of lipid accumulation products as a predictor of osteoporosis.

14 May 2025

What’s stopping restaurants from offering healthier kids’ meals?

Dutch researchers explored what motivates restaurants to offer healthier kids’ meals and what stands in the way. While willingness is high, perceived low demand, food waste, and operational barriers hold many back.

13 May 2025

Lipid buildup predicts weaker bones once it passes a critical threshold

A large cross-sectional study using NHANES data found a non-linear negative relationship between lipid accumulation product (LAP) and lumbar spine bone mineral density (BMD). The association became significant only above a threshold value (ln-LAP > 2.846), independent of BMI.

12 May 2025

Simple vest could help older adults maintain weight loss long term

Wearing a weighted vest during a 6-month calorie-restricted weight loss program helped older adults with obesity regain less weight over 24 months compared to those on diet alone. This benefit may be due to better preservation of resting metabolic rate during the intervention.

12 May 2025

Comprehensive treatment approach helps patients manage rheumatoid arthritis

Although rheumatoid arthritis is an autoimmune disease with no cure, a tailored, multidisciplinary treatment approach at Cedars-Sinai's Inflammatory Arthritis Clinical Center helps patients get back to the activities they enjoy.

7 May 2025