Osteoarthritis News and Research

Latest Osteoarthritis News and Research

AI system predicts future knee X-rays to transform osteoarthritis care

An AI system that can predict what a patient's knee X-ray will look like a year in the future could transform how millions of people with osteoarthritis understand and manage their condition, according to research by the University of Surrey.

14 Oct 2025

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

The strong opioid painkiller, tramadol, is not that effective at easing chronic pain for which it's widely prescribed, finds a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine.

7 Oct 2025

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

A new clinical trial finds that people with a limited number of metastases from recurrent prostate cancer lived significantly longer without disease progression when they received a radiopharmaceutical drug before targeted radiation, compared with radiation alone.

29 Sep 2025

Low-dose radiation therapy may be a suitable option for people with painful knee osteoarthritis

A single course of low-dose radiation therapy may provide a safe and effective alternative treatment option for people with painful knee osteoarthritis according to a new randomized, placebo-controlled clinical trial.

29 Sep 2025

Single-cell RNA sequencing reveals key genes and potential targeted drugs for OA treatment

Researchers from the Department of Orthopedics at Taicang TCM Hospital Affiliated to Nanjing University of Chinese Medicine have made significant strides in understanding the molecular mechanisms underlying osteoarthritis (OA).

26 Sep 2025

Healthy habits linked to younger brain age

Your chronological age may say 65, but your brain could be acting a decade younger - or older - depending on your life experiences.

25 Sep 2025

Population aging identified as largest contributor to the increasing burden of musculoskeletal disorders

Novel research shows that in approximately one third of countries and territories worldwide, population aging was the largest contributor to the growing burden of musculoskeletal disorders from 1990 to 2021.

16 Sep 2025

GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity

A new study led by investigators at Mass General Brigham finds that adding novel weight loss GLP-1 drugs semaglutide and tirzepatide to usual care represents a cost-effective treatment strategy for people with knee osteoarthritis and obesity, with tirzepatide providing greater health benefits at lower cost compared to semaglutide.

16 Sep 2025

Healthy diet found to reduce chronic pain beyond weight loss

We all know the benefits of a healthy diet. But new research from the University of South Australia shows that eating nutritious food is about far more than ticking off the five food groups – it can also significantly reduce chronic pain.

9 Sep 2025

Gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

1 Sep 2025

Healthy gut bacteria capsules show long-term benefits for obese teenagers

Can a capsule of healthy gut bugs change the future of obesity treatment? New findings from the University of Auckland’s Liggins Institute suggest it might.

29 Aug 2025

How a single gene reshapes pain perception through polyamine signaling

Researchers have identified SLC45A4 as a neuronal polyamine transporter genetically linked to human chronic pain. Loss of this gene in mice disrupts polyamine balance, alters spinal GABA levels, and reduces heat and tonic pain sensitivity.

24 Aug 2025

Evidence review questions ketamine’s role in chronic pain treatment

A Cochrane review assessed ketamine and other NMDA receptor antagonists for chronic non-cancer pain. The evidence was low to very low certainty, showing no clear pain relief and potential adverse effects with intravenous ketamine.

21 Aug 2025

Genicular artery embolization relieves chronic knee pain caused by osteoarthritis

A procedure performed under mild sedation in less than two hours by an interventional radiologist relieves chronic knee pain caused by osteoarthritis, an NYU Langone Health study shows.

14 Aug 2025

New research explores foot positioning to treat knee osteoarthritis

Gait analysis and pain measures show that subtly adjusting the angle of the foot during walking may reduce knee pain caused by osteoarthritis. This approach may also slow progression of the condition, an uncurable disease in which the cartilage cushion inside a joint breaks down.

13 Aug 2025

Personalized gait retraining reduces pain and slows knee damage in osteoarthritis

Nearly a quarter of people over the age of 40 experience painful osteoarthritis, making it a leading cause of disability in adults.

12 Aug 2025

New Canadian guideline highlights expanded role of obesity medications

"Pharmacotherapy can help people living with obesity improve overall health, not just lose weight," says Dr. Sue D. Pedersen, MD, endocrinologist and obesity medicine specialist in Calgary, and lead author of this guideline. "The goal of obesity medications is to improve metabolic, mechanical, and/or mental health, and improve quality of life, incorporating treatment goals that are important to each individual patient."

11 Aug 2025

Spinning's positive impact on hip osteoarthritis uncovered

A new study by Bournemouth University (BU) and University Hospitals Dorset (UHD) has revealed the benefits of spinning for patients with hip osteoarthritis. The study was funded by the National Institute for Health Research (NIHR) and will be published in Lancet Rheumatology at 23:30 UK time on Thursday 31st July 2025.

1 Aug 2025

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Elenagen™, a novel DNA plasmid therapy that previously demonstrated high clinical benefit and low toxicity in cancer patients, has now shown significant promise in alleviating chronic pain demonstrating a 90% success rate.

23 Jul 2025

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

Landmark trials have shown that GLP-1 receptor agonists, originally developed for diabetes and weight loss, also provide significant benefits for cardiovascular, kidney, liver, joint, and sleep-related diseases. These effects extend beyond weight loss, suggesting anti-inflammatory mechanisms with broad potential for managing chronic diseases.

22 Jul 2025

Osteoarthritis News and Research

Latest Osteoarthritis News and Research

AI system predicts future knee X-rays to transform osteoarthritis care

Tramadol found to offer limited relief for chronic pain while raising risk of serious side effects

Combining radiopharmaceuticals with targeted radiation improves progression-free survival in prostate cancer patients

Low-dose radiation therapy may be a suitable option for people with painful knee osteoarthritis

Single-cell RNA sequencing reveals key genes and potential targeted drugs for OA treatment

Healthy habits linked to younger brain age

Population aging identified as largest contributor to the increasing burden of musculoskeletal disorders

GLP-1 drugs may offer cost-effective treatment for people with knee osteoarthritis and obesity

Healthy diet found to reduce chronic pain beyond weight loss

Gait retraining reduces pain and slows knee damage in osteoarthritis

Healthy gut bacteria capsules show long-term benefits for obese teenagers

How a single gene reshapes pain perception through polyamine signaling

Evidence review questions ketamine’s role in chronic pain treatment

Genicular artery embolization relieves chronic knee pain caused by osteoarthritis

New research explores foot positioning to treat knee osteoarthritis

Personalized gait retraining reduces pain and slows knee damage in osteoarthritis

New Canadian guideline highlights expanded role of obesity medications

Spinning's positive impact on hip osteoarthritis uncovered

Novel DNA plasmid therapy shows high success rate in treating chronic pain in dogs

Can one drug do it all? Reviewing the expanding clinical universe of GLP-1 agonists

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

Osteoarthritis News and Research

Latest Osteoarthritis News and Research

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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