Primary Care News and Research

Latest Primary Care News and Research

Rethinking chronic disease management in older adults

Effectively managing chronic conditions like diabetes and hypertension can greatly improve quality of life, reduce complications and extend longevity for older adults.

20 Aug 2025

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Texas Children's is pleased to announce that a three-year-old girl has been successfully treated with the first-ever FDA-approved gene therapy treatment for AADC deficiency.

19 Aug 2025

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Patients in a Phase I/II clinical trial conducted by UMass Chan Medical School of a dual vector gene therapy for GM2 gangliosidosis, which includes Tay-Sachs and Sandhoff diseases, exhibited a biochemical correction of the disease with minimal adverse reactions.

18 Aug 2025

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

A new study, led by researchers at Children's Hospital of Philadelphia (CHOP), identified tiny pieces of messenger RNA that are missing in pediatric high-grade glioma tumors but not in normal brain tissues.

18 Aug 2025

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Researchers from Children's Hospital of Philadelphia (CHOP) and Children's Hospital Colorado have found that better control of chronic eosinophilic esophagitis (EoE)-associated inflammation during childhood leads to less stiffening of the esophagus, resulting in fewer disease complications.

18 Aug 2025

Portable device enables at-home monitoring of Parkinson’s disease symptoms

The number of people living with Parkinson's disease globally has doubled in the past 25 years.

17 Aug 2025

AI voice test could help spot dangerous throat lesions before symptoms appear

Researchers at Oregon Health and Science University found that variability in the harmonic-to-noise ratio (HNR) of speech could help distinguish benign from malignant vocal fold lesions, offering a potential early detection biomarker. The exploratory study used AI to analyze acoustic features from the Bridge2AI-Voice dataset and found differences most pronounced in male participants.

14 Aug 2025

Growing use of AI scribes among New Zealand GPs raises ethical and legal questions

Many New Zealand GPs have taken up the use of AI scribes to transcribe patient notes during consultations despite ongoing challenges with their legal and ethical oversight, data security, patient consent, and the impact on the doctor-patient relationship, a study led by the University of Otago, Wellington – Ōtākou Whakaihu Waka, Pōneke has found.

14 Aug 2025

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Preventing and managing high blood pressure with healthy lifestyle behaviors, such as following a heart-healthy diet including reducing salt intake, staying physically active, maintaining a healthy weight and managing stress—combined with early treatment with medication to lower blood pressure if necessary—are recommended to reduce the risk of heart attack, stroke, heart failure, kidney disease, cognitive decline and dementia, according to a new clinical guideline published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

14 Aug 2025

Primary care could help meet growing needs of cancer survivors

Thanks to new advances in cancer care, more and more people are surviving cancer, with a projected total of 22.5 million survivors by 2032.

13 Aug 2025

Doctor’s white coats remain a symbol of trust despite growing acceptance of scrubs

Patients are still more likely to trust doctors and consider them more professional when they wear white coats, although women doctors in this attire are often misidentified as nurses or medical assistants, finds a review of the available research on the topic, published in the open access journal BMJ Open.

13 Aug 2025

Researchers find CFI deficiency alarmingly high in old order Amish

Researchers from Children's Hospital of Philadelphia (CHOP) and the Clinic for Special Children found that complement factor I (CFI) deficiency, an ultra-rare genetic disorder that can cause debilitating neuroinflammation, is more than 4500 times more likely to be found in individuals of Old Order Amish ancestry than the rest of the global population.

13 Aug 2025

Long COVID linked to lasting financial hardship and work disruption

While the economic impact of the COVID-19 pandemic continues to be widely studied and debated, the financial toll of the COVID-19 pandemic for individual patients is less understood.

12 Aug 2025

Research finds long-term health challenges in survivors of childhood cancer

Researchers at City of Hope, one of the largest and most advanced cancer research and treatment organizations in the United States with its National Medical Center ranked among the nation's top cancer centers by U.S. News & World Report, today published a new study which found that some survivors of childhood cancer are more at risk for serious health issues as they grow older, including new cancers and chronic conditions like heart disease.

11 Aug 2025

Researchers develop machine learning models to identify biomarkers for chronic fatigue syndrome

When cells expire, they leave behind an activity log of sorts: RNA expelled into blood plasma that reveal changes in gene expression, cellular signaling, tissue injury and other biological processes.

11 Aug 2025

Why young Americans dread turning 26: Health insurance chaos

Amid the challenges of adulthood, one rite of passage is unique to the United States: the need to find your own health insurance by the time you turn 26.

11 Aug 2025

A guide to finding insurance at 26‌

It was supposed to be easier than this. When the Affordable Care Act was passed in March 2010, the goal was to help more Americans get health insurance. And, indeed, the establishment of online marketplaces and a broadening of the eligibility guidelines for Medicaid accomplished that.

11 Aug 2025

Expanded vaccine screening in emergency departments could benefit underserved populations

About 49% of people are unaware of one or more vaccines recommended for them. Further, 86% have not received one or more of these vaccines.

7 Aug 2025

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

The 2024 European clinical practice guidelines introduce a pivotal terminology shift, replacing NAFLD (non-alcoholic fatty liver disease) with MASLD (metabolic dysfunction-associated steatotic liver disease) and NASH with MASH (metabolic dysfunction-associated steatohepatitis).

7 Aug 2025

Survey reveals persistent challenges of IBS on daily life and productivity

Despite social media helping to increase awareness of irritable bowel syndrome (IBS) among the public (81% of health care providers agree) and advancements in treatment over the past decade, IBS symptoms continue to significantly impact patients' daily lives and productivity, according to a new survey released by the American Gastroenterological Association (AGA), in partnership with The Harris Poll, a Stagwell (STGW) agency.

7 Aug 2025

Primary Care News and Research

Latest Primary Care News and Research

Rethinking chronic disease management in older adults

Texas Children’s successfully treats AADC deficiency using FDA-approved gene therapy

Dual vector gene therapy for GM2 gangliosidosis shows encouraging results in clinical trial

Missing messenger RNA fragments unlock new immunotherapy targets in pediatric brain tumors

Better control of childhood EoE-associated inflammation reduces esophagus stiffening and complications

Portable device enables at-home monitoring of Parkinson’s disease symptoms

AI voice test could help spot dangerous throat lesions before symptoms appear

Growing use of AI scribes among New Zealand GPs raises ethical and legal questions

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Primary care could help meet growing needs of cancer survivors

Doctor’s white coats remain a symbol of trust despite growing acceptance of scrubs

Researchers find CFI deficiency alarmingly high in old order Amish

Long COVID linked to lasting financial hardship and work disruption

Research finds long-term health challenges in survivors of childhood cancer

Researchers develop machine learning models to identify biomarkers for chronic fatigue syndrome

Why young Americans dread turning 26: Health insurance chaos

A guide to finding insurance at 26‌

Expanded vaccine screening in emergency departments could benefit underserved populations

Updated multidisciplinary European guidelines redefine MASLD diagnosis and treatment

Survey reveals persistent challenges of IBS on daily life and productivity

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Primary Care News and Research

Latest Primary Care News and Research

AI in Healthcare: How generative tools are transforming clinical practice

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Newsletters you may be interested in