Psoriasis

Psoriasis is a chronic, immune-mediated disease that results from the overproduction of skin cells, resulting in their accumulation on the surface of the skin, which causes red, scaly plaques that may itch and bleed. It is estimated that approximately 7.5 million Americans and nearly 3 percent of the world's population are living with psoriasis and nearly one-quarter of those people have cases that are considered moderate to severe.

What is Psoriasis?

Psoriasis represents chronic inflammatory skin condition with complex pathophysiology and significant genetic background. This disease is characterized by erythematous, scaling lesions that exhibit variable patterns and distribution, as well as different clinical phenotypes. Psoriasis can significantly influence the quality of life and usually requires lifetime control.

Psoriasis Types

Psoriasis Treatment

Psoriasis Topical Treatment

Psoriasis Systemic Treatment

Psoriasis Prognosis

Psoriasis Phototherapy

Psoriasis Photochemotherapy

Psoriasis Historical Treatment

Psoriasis Genetic Factors

Psoriasis Epidemiology

Psoriasis Drug Development

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Psoriasis Diagnosis

Psoriasis Clinical Classification

Psoriasis Cause

Psoriasis Alternative Therapy

Living With Psoriasis

Diet and Psoriasis

Latest Psoriasis News and Research

Study uncovers dual role for molecule involved in autoimmune eye disease

The inflammatory molecule interleukin-17A (IL-17A) triggers immune cells that in turn reduce IL-17A's pro-inflammatory activity, according to a study by National Eye Institute researchers.

23 Jul 2020

siRNA-based treatment can reduce psoriasis symptoms

Psoriasis, a chronic skin condition that causes itchy, red, scaly patches, afflicts more than 8 million Americans and 125 million people worldwide.

23 Jul 2020

Newly identified gene biomarker can distinguish atopic dermatitis and psoriasis with excellent accuracy

Mount Sinai researchers have pinpointed a single gene biomarker, nitride oxide synthase 2 (NOS2) that can distinguish atopic dermatitis (AD) and psoriasis with 100 percent accuracy using adhesive tape strips, a non-invasive alternative to skin biopsy. The research will be published online today in the Journal of Allergy and Clinical Immunology.

21 Jul 2020

High-resolution TB-PET/CT scanner reveals complete picture of systemic inflammatory arthritis

For the first time, physicians can examine the systemic burden of inflammatory arthritis simultaneously across all joints and organ systems, using the high-sensitivity, high-resolution uEXPLORER total-body positron emission tomography/computed tomography (TB-PET/CT) scanner.

13 Jul 2020

National Psoriasis Foundation announces $3.28 million in research grants and fellowships

The National Psoriasis Foundation, NPF, is proud to announce the awarding of $3.28 million in research grants and fellowships in 2020.

6 Jul 2020

2021 health plans granted leeway to limit consumers’ benefit from drug coupons

Without medication to manage her plaque psoriasis, Jennifer Brown's face, scalp, trunk and neck periodically become covered in painful red, flaky patches so dry they crack and bleed.

6 Jul 2020

Developing Vaccines and Therapeutics by Exploiting Structure in Spherical Nucleic Acids

An interview discussing the use of spherical nucleic acids (SNAs) and what they show about the importance of structure in pharmaceutical development.

From Pittcon 2 Jul 2020

New microscopy technique can be used to study the progression of wound healing

Researchers at the GSK Center for Optical Molecular Imaging have developed a new microscope that looks at the different parameters that change during wound healing. They hope to use this technique to understand how skin disorders, such as foot ulcers in diabetic patients and psoriasis, can be treated.

17 Jun 2020

Corrona Psoriasis Registry to present studies at AAD Virtual Meeting Experience

The Corrona® Psoriasis Registry, a joint collaboration between the National Psoriasis Foundation, NPF, and Corrona, LLC, the leading sponsor of registries in immune-mediated diseases, announces that studies from the registry will be presented at the American Academy of Dermatology Virtual Meeting Experience taking place June 12-14, 2020.

12 Jun 2020

Georgia State researcher receives $1.95 million NIH grant to study cause of autoimmunity

Dr. Leszek Ignatowicz, a professor in the Institute for Biomedical Sciences at Georgia State University, has received a five-year, $1.95 million federal grant to study what causes autoimmunity in the human body.

8 Jun 2020

Study uncovers link between psoriasis and joint disease

A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure.

8 Jun 2020

Trial results show efficacy of netakimab for treating moderate-to-severe plaque psoriasis

Netakimab is a humanized anti-interleukin 17A antibody approved for the treatment of moderate-to-severe plaque psoriasis.

5 Jun 2020

Psoriasis has more impact on patients' mental health than their skin symptoms

Treatment of the common disease psoriasis, usually focuses on treating the skin. However, psoriasis patients often have other physical diseases that can bring on depression, anxiety, and suicide.

4 Jun 2020

Researchers develop novel method to diagnose and monitor autoimmune disorders

Researchers from Prokhorov General Physics Institute of the Russian Academy of Sciences and the Moscow Institute of Physics and Technology have developed a novel method for diagnosing and monitoring autoimmune disorders.

19 May 2020

Biologic drug can help treat contact dermatitis

APOSEC it is a biologic wound-healing agent developed by thoracic surgeon Hendrik Jan Ankersmit from MedUni Vienna.

15 May 2020

Human to Labskin Skin Models for Dermatology Research

A Human Skin Equivalent (HSE) skin model used for dermatology research, made from the same primary human cells but grown to a defined specification in a laboratory and not as complex as Human skin, lacking hair follicles and immune cells.

From Labskin 6 May 2020

Researchers show basic lymphatic vessel functionality is the same in mice and humans

In an international collaboration, researchers from Uppsala University have mapped the lymph node lymphatic vessels in mice and humans down to the level of individual cells.

5 May 2020

Many phase II trials overestimate drug efficacy, pose a barrier in drug licensing

Based on a systematic analysis of trials related to rheumatoid arthritis and psoriasis arthritis, a MedUni Vienna study group at the Division of Rheumatology at MedUni Vienna/Vienna General Hospital was able to show that many clinical phase II trials systematically overestimate the efficacy of therapeutics, so that the results of subsequent phase III trials can often be disappointing. Essentially this situation also applies in many other areas.

21 Apr 2020

Lipid aids healing of scratches on the cornea

A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.

26 Mar 2020

Study unravels molecular mechanism behind autoimmune and inflammatory diseases

A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis.

17 Mar 2020