Psoriasis

Psoriasis is a chronic, immune-mediated disease that results from the overproduction of skin cells, resulting in their accumulation on the surface of the skin, which causes red, scaly plaques that may itch and bleed. It is estimated that approximately 7.5 million Americans and nearly 3 percent of the world's population are living with psoriasis and nearly one-quarter of those people have cases that are considered moderate to severe.

What is Psoriasis?

Psoriasis represents a chronic inflammatory skin condition with a complex pathophysiology and significant genetic background.

Psoriasis Clinical Classification

Psoriasis Systemic Treatment

Diet and Psoriasis

Psoriasis Drug Development

Psoriasis Genetic Factors

Living With Psoriasis

Psoriasis Topical Treatment

Psoriasis Treatment

Psoriasis Prognosis

What causes Psoriasis?

Psoriasis Historical Treatment

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Psoriasis Alternative Therapy

Psoriasis Photochemotherapy

Psoriasis Epidemiology

Psoriasis Diagnosis

Psoriasis Phototherapy

Psoriasis Types

Latest Psoriasis News and Research

Study uncovers how inflammation in brain blood vessels exacerbates damage in vascular dementia

A new study from UCLA Health has uncovered how inflammation in brain blood vessels exacerbates damage in vascular dementia and demonstrated that targeting this process with a repurposed drug can promote brain repair and functional recovery in mice.

1 Jul 2025

Study finds nearly double risk of depression and anxiety in autoimmune patients

Living with an autoimmune disease is linked to a near doubling in the risk of persistent mental health issues, such as depression, generalised anxiety, and bipolar disorder, with these risks higher in women than in men, finds a large population-based UK study, published in the open access journal BMJ Mental Health.

25 Jun 2025

Early intensive therapy shows promise in psoriatic arthritis patients with poor prognostic factors

Is there a benefit to early bDMARD? In psoriatic arthritis (PsA) EULAR - The European Alliance of Associations for Rheumatology - recommends a treat-to-target approach, and suggests more intensive therapy for people with poor prognostic factors, depending on the disease presentation.

11 Jun 2025

Study: More expectant mothers begin pregnancy with autoimmune conditions

Thousands more UK women who are having children have been diagnosed with an autoimmune condition now compared to the beginning of the millennium.

2 Jun 2025

Abdominal fat emerges as independent risk factor for psoriasis in women

Researchers have found that central body fat, especially around the abdomen, is more strongly linked to psoriasis risk than total body fat, particularly in women.

27 May 2025

Residual inflammation can linger in psoriasis patients despite skin treatment

New research shows that in patients with psoriasis, even though their skin responds well to treatment with biologics, inflammation can linger, leading to broader health implications such as obesity and cardiovascular and fatty liver disease.

20 May 2025

New study identifies wedelolactone as a potent topical treatment for psoriasis

Announcing a new publication for Acta Materia Medica journal. Psoriasis is a chronic inflammatory disorder for which phosphodiesterase-4 (PDE4) inhibitors have emerged as promising therapeutic agents due to an ability to regulate inflammatory signaling pathways.

13 May 2025

Study reveals potential new strategy to prevent or slow progression of Type 1 diabetes

A study co-led by Indiana University School of Medicine researchers presents a potential new strategy to prevent or slow the progression of Type 1 diabetes by targeting an inflammation-related protein known to drive the disease.

7 May 2025

Cardiovascular mortality higher in women with rheumatoid arthritis and lupus

Women with the autoimmune diseases rheumatoid arthritis, lupus or systemic sclerosis may have a higher rate of death related to cardiovascular disease than men with the autoimmune diseases, according to new research published in the American Heart Association's journal Circulation: Cardiovascular Quality and Outcomes.

6 May 2025

Ultra-processed foods linked to higher psoriasis risk

A large UK Biobank study found that higher consumption of ultra-processed foods (UPFs) is associated with an increased risk of developing psoriasis. Each 10% increase in UPF intake raised psoriasis risk by 6%, with obesity and inflammation partially mediating this effect.

4 May 2025

Why skin shame matters more than symptoms in chronic skin conditions

A new study in Scientific Reports reveals that skin shame is a key psychological burden for people with atopic dermatitis and psoriasis. It significantly affects quality of life, even more than anxiety or depression, especially when disease severity is high.

22 Apr 2025

FDA approved anti-inflammatory drug shows promise for treating alcohol use disorder and pain

A preclinical study from scientists at Scripps Research finds that a drug already FDA-approved for treating inflammatory conditions may help reduce both alcohol intake and pain sensitivity-two issues that commonly co-occur with alcohol use disorder (AUD).

22 Apr 2025