Psoriasis

Psoriasis is a chronic, immune-mediated disease that results from the overproduction of skin cells, resulting in their accumulation on the surface of the skin, which causes red, scaly plaques that may itch and bleed. It is estimated that approximately 7.5 million Americans and nearly 3 percent of the world's population are living with psoriasis and nearly one-quarter of those people have cases that are considered moderate to severe.

What is Psoriasis?

Psoriasis represents chronic inflammatory skin condition with complex pathophysiology and significant genetic background. This disease is characterized by erythematous, scaling lesions that exhibit variable patterns and distribution, as well as different clinical phenotypes. Psoriasis can significantly influence the quality of life and usually requires lifetime control.

Psoriasis Types

Psoriasis Treatment

Psoriasis Topical Treatment

Psoriasis Systemic Treatment

Psoriasis Prognosis

Psoriasis Phototherapy

Psoriasis Photochemotherapy

Psoriasis Historical Treatment

Psoriasis Genetic Factors

Psoriasis Epidemiology

Psoriasis Drug Development

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Psoriasis Diagnosis

Psoriasis Clinical Classification

Psoriasis Cause

Psoriasis Alternative Therapy

Living With Psoriasis

Diet and Psoriasis

Latest Psoriasis News and Research

Lipid aids healing of scratches on the cornea

A species of a lipid that naturally helps skin injuries heal appears to also aid repair of common corneal injuries, even when other conditions, like diabetes, make healing difficult, scientists report.

26 Mar 2020

Study unravels molecular mechanism behind autoimmune and inflammatory diseases

A study by the research team of Prof. Geert van Loo (VIB-UGent Center for Inflammation Research) has unraveled a critical molecular mechanism behind autoimmune and inflammatory diseases such as rheumatoid arthritis, Crohn's disease, and psoriasis.

17 Mar 2020

Research reveals how skin cells embark on a swift yet elaborate death

Skin is our body's most ardent defender against pathogens and other external threats. Its outermost layer is maintained through a remarkable transformation in which skin cells swiftly convert into squames--flat, dead cells that provide a tight seal between the living portion of the skin and the world outside.

13 Mar 2020

Cream infused with microscopic STAR particles could facilitate better treatment of skin diseases

Skin diseases affect half of the world's population, but many treatments are not effective, require frequent injections, or cause significant side effects.

10 Mar 2020

New immune cell with 'Jekyll and Hyde properties' identified

Scientists at Trinity College Dublin have identified a rare, new cell in the immune system with "Jekyll and Hyde properties". These cells play a key protective role in immunity to infection but - if unregulated - also mediate tissue damage in autoimmune disorders.

27 Feb 2020

Cancer risk in psoriatic patients

A new study published in February 2020 in the journal JAMA Dermatology reports that there is a 21% increased risk of cancer in patients with psoriasis, but not with psoriatic arthritis alone.

19 Feb 2020

Microbiome in dermis skin layer is the same regardless of age and gender

In the dermis skin layer, the same bacteria are found across age and gender. This has been shown by researchers from the University of Copenhagen in a new study which has studied skin samples from knees and hips.

12 Feb 2020

Western diet rich in fat and sugar may lead to inflammatory skin diseases

A Western diet rich in fat and sugar may lead to inflammatory skin diseases such as psoriasis, a study by UC Davis Health researchers has found.

10 Feb 2020

Discovery could unlock new ways to treat a rare blood disease

A cancer researcher at the University of Alberta has made a discovery that could unlock new ways to treat a rare blood disease.

27 Jan 2020

Holistic Approaches to Psoriasis Treatment

Holistic approaches to psoriasis treatment involves lifestyle advice about weight, smoking, alcohol, sleep, exercise, and other factors.

From Janssen Global Services, LLC 22 Jan 2020

Scientists secure funding to develop better methods for evaluation of topically applied drugs

A team of leading scientists from Bath University UK, the UK's National Physical Laboratory, and the Colorado School of Mines USA has secured funding from the US Food and Drug Administration to develop better methods to assess the performance of topically applied drug products.

10 Jan 2020

Targeting VEGFA signaling in the epidermis can prevent psoriasis development

Psoriasis is a frequent skin inflammatory disorder affecting 3% of the population. Psoriasis is characterized by hyperproliferation and defect of epidermal differentiation, leading to the scaly appearance of the skin. The psoriasis skin also presents an increase in blood vessels, leading to the redness of the skin lesions and is associated with immune infiltration.

9 Jan 2020

Dendritic cells could lead to better treatments for persistent infections, cancer

Autoimmune disorders such as rheumatoid arthritis, psoriasis, and Crohn's disease plague tens of millions of Americans and are the result of the body's immune system, whose role is to fight against disease-causing pathogens, turning against itself.

12 Dec 2019

Research suggests new strategies for developing psoriasis therapies

Psoriasis is a skin disorder that affects at least 100 million individuals worldwide. Its economic impact is more than $10 billion annually in the U.S. alone.

11 Dec 2019

NeutroCure project aims to cure inflammatory disease with neutrophils

Curing disease with neutrophils; this is the goal of the NeutroCure project. How will that work? "Neutrophils have a yin yang character," explained Andrés Hidalgo, whose team at the Centro Nacional de Investigaciones Cardiovasculares is one of six member groups participating in this project coordinated by Andriy Mokhir Friedrich from Alexander University, Germany.

5 Dec 2019

Study finds major sex differences when considering link between psoriasis and metabolic disorders

An analysis published in the Journal of the European Academy of Dermatology and Venereology revealed considerable sex differences when considering links between psoriasis and metabolic disorders.

4 Dec 2019

Researchers uncover critical role of PKM2 protein in multiple inflammatory diseases

A research team in Trinity College Dublin has uncovered a critical role for a protein called 'PKM2' in the regulation of immune cell types at the heart of multiple inflammatory diseases.

21 Nov 2019

New insights into how immune system and inflammation play a role in PD

Relatively new research findings indicating that the earliest stages of Parkinson's disease (PD) may occur in the gut have been gaining traction in recent years. In a review published in the Journal of Parkinson's Disease, Tomasz Brudek, PhD, evaluates evidence for the association between inflammatory bowel disease (IBD) and PD and proposes directions for future research.

14 Nov 2019

Age of psoriasis onset decides if the skin or joints act up first

People with psoriatic arthritis may initially present with either psoriasis or arthritis as the first symptom/sign of this illness. Now, a new study presented at the 2019 ACR/ARP Annual Meeting shows that the age at which psoriasis develops is a key predictor of which shows up first. Early-onset psoriasis is not strongly associated with arthritis while late-onset psoriasis is.

11 Nov 2019

Research highlights benefits of oral prednisolone in patients with hand osteoarthritis

Research presented at the 2019 ACR/ARP Annual Meeting found that a six-week treatment with low-dose oral prednisolone substantially improves pain and decreases signs of inflammation in patients with painful hand osteoarthritis.

11 Nov 2019