Schizophrenia News and Research

Latest Schizophrenia News and Research

Rates of smoking, drinking and drug use are higher among people with psychotic disorders

In the largest ever assessment of substance use among people with severe psychiatric illness, researchers at Washington University School of Medicine in St. Louis and the University of Southern California have found that rates of smoking, drinking and drug use are significantly higher among those who have psychotic disorders than among those in the general population.

2 Jan 2014

Researchers find inhibition of basic cellular process that contributes to schizophrenia

Surprisingly little is known about schizophrenia. It was only recognized as a medical condition in the past few decades, and its exact causes remain unclear. Since there is no objective test for schizophrenia, its diagnosis is based on an assortment of reported symptoms.

30 Dec 2013

Schizophrenia brain marker matches genetic risk

Polygenic risk for schizophrenia correlates with neural inefficiency in the left dorsolateral prefrontal cortex, say researchers.

24 Dec 2013

Treating depression fails to reverse cognitive deficits in bipolar disorder

Successful treatment of depression with total sleep deprivation does not improve neuropsychologic deficits in bipolar patients, despite improving clinical symptoms, Italian researchers report.

24 Dec 2013

Viewpoints: Impact of 'meddling with' health law; antibiotics on farms; 'Let thirtysomethings' join Medicare

[A]ll of these last-minute policy shifts confuse people who were already struggling to understand a complex new system, ... The cumulative effect is that at least some people - we hope not many - will misunderstand their responsibilities under the law or be deterred from seeking coverage. The biggest danger is that the Obama administration is encouraging politicians to meddle in the health-care system every time a few vocal constituents get upset about its requirements (12/21).

24 Dec 2013

Variation in oxytocin receptor gene influences face recognition skills, study finds

New findings suggest the oxytocin receptor, a gene known to influence mother-infant bonding and pair bonding in monogamous species, also plays a special role in the ability to remember faces. This research has important implications for disorders in which social information processing is disrupted, including autism spectrum disorder. In addition, the finding may lead to new strategies for improving social cognition in several psychiatric disorders.

24 Dec 2013

Humans with high motor excitability have better working memory

Humans with a high motor excitability have a better working memory than humans with a low excitability. This was shown in a study conducted by scientists from the Transfacultary Research Platform at the University of Basel. By measuring the motor excitability, conclusions can be drawn as to the general cortical excitability - as well as to cognitive performance.

23 Dec 2013

Further boost for copy number variant role in schizophrenia

A large study confirms that 11 previously identified copy number variants are likely associated with schizophrenia.

20 Dec 2013

Newly-discovered selective process may explain why brain function does not deteriorate

As we grow older, our brains undergo a major reorganisation reducing the connections in the brain. Studying people up to the age of 40, scientists led by Dr Marcus Kaiser and Ms Sol Lim at Newcastle University found that while overall connections in the brain get streamlined, long-distance connections that are crucial for integrating information are preserved.

20 Dec 2013

Head injuries increase risk for psychiatric disorders

A Danish study of a large cohort of individuals who presented at hospital with head injuries has found that they were at increased risk for later developing schizophrenia, bipolar disorder, depression, and organic mental disorders.

19 Dec 2013

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Rare copy-number variants that confer a high risk for schizophrenia or autism are associated with impaired cognition in carriers without psychiatric disorders, researchers report in Nature.

19 Dec 2013

Diet may not fully explain cardiometabolic problems in bipolar disorder

The diet of patients with bipolar disorder or schizophrenia seems to be no worse than that of mentally healthy people, a study suggests.

19 Dec 2013

Omeros' OMS721 receives FDA orphan drug designation for prevention of TMAs

Omeros Corporation today announced that OMS721, the company's lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-2 (MASP-2), the key regulator of the lectin pathway of the immune system, has received orphan drug designation from the U.S. Food and Drug Administration for prevention of complement-mediated thrombotic microangiopathies.

18 Dec 2013

DCC gene involved in adolescent brain development may play a role in mental health vulnerability

As many parents of mentally ill adults will confirm anecdotally, the first symptoms of "something not quite right" with their children begin to appear during the teen years. It is known that during this teenaged phase of brain development, adolescents are particularly vulnerable to psychiatric disorders, including schizophrenia, depression and drug addiction.

17 Dec 2013

Rich club disconnectivity may be ‘core’ schizophrenia feature

The impaired “rich club” connectivity observed in the brains of patients with schizophrenia is also present in their unaffected siblings, report researchers.

17 Dec 2013

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Investigators at The Feinstein Institute for Medical Research have discovered for the first time, direct evidence of a genetic overlap between schizophrenia and general cognitive ability. The findings are published online in Molecular Psychiatry.

17 Dec 2013

Targacept reports top-line results from TC-5619 Phase 2b trial for negative symptoms in schizophrenia

Targacept, Inc., a clinical-stage biopharmaceutical company developing novel NNR Therapeutics, today announced top-line results from a Phase 2b clinical trial of TC-5619 as an augmentation therapy for the treatment of negative symptoms of schizophrenia.

17 Dec 2013

Secondary conditions can become deadly and affect how long HIV patients stay in hospital

A University of Arkansas researcher and her colleagues have found that secondary conditions and diseases that could become deadly significantly affect how long HIV patients stay in the hospital.

17 Dec 2013

Drug abuse appears to foster brain changes that resemble schizophrenia

Teens who were heavy marijuana users -- smoking it daily for about three years -- had abnormal changes in their brain structures related to working memory and performed poorly on memory tasks, reports a new Northwestern Medicine- study.

16 Dec 2013

Psychiatrists increasingly refuse to accept private insurance as payment

Access to mental health care has become a prominent issue in Congress following mass shootings around the country. But a new study in JAMA Psychiatry, led by researchers at Weill Cornell Medical College, suggests that unless those in need of help have deep pockets, they might have a hard time finding a psychiatrist that will provide the needed services.

13 Dec 2013

Schizophrenia News and Research

Latest Schizophrenia News and Research

Rates of smoking, drinking and drug use are higher among people with psychotic disorders

Researchers find inhibition of basic cellular process that contributes to schizophrenia

Schizophrenia brain marker matches genetic risk

Treating depression fails to reverse cognitive deficits in bipolar disorder

Viewpoints: Impact of 'meddling with' health law; antibiotics on farms; 'Let thirtysomethings' join Medicare

Variation in oxytocin receptor gene influences face recognition skills, study finds

Humans with high motor excitability have better working memory

Further boost for copy number variant role in schizophrenia

Newly-discovered selective process may explain why brain function does not deteriorate

Head injuries increase risk for psychiatric disorders

Neurocognitive abnormalities ‘fundamental’ to schizophrenia

Diet may not fully explain cardiometabolic problems in bipolar disorder

Omeros' OMS721 receives FDA orphan drug designation for prevention of TMAs

DCC gene involved in adolescent brain development may play a role in mental health vulnerability

Rich club disconnectivity may be ‘core’ schizophrenia feature

Researchers discover direct evidence of genetic overlap between cognitive ability and schizophrenia

Targacept reports top-line results from TC-5619 Phase 2b trial for negative symptoms in schizophrenia

Secondary conditions can become deadly and affect how long HIV patients stay in hospital

Drug abuse appears to foster brain changes that resemble schizophrenia

Psychiatrists increasingly refuse to accept private insurance as payment

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