Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Prognosis

Schizophrenia Signs and Symptoms

Schizophrenia Diagnosis

Schizophrenia Neural Processes

Schizophrenia Causes

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Latest Schizophrenia News and Research

Study validates stem cell models for neurological diseases

In a comprehensive Genomic Press perspective (peer-reviewed review) article, an international team of neuroscientists has outlined crucial validity standards that could transform how researchers use stem cell technology to study devastating brain disorders.

15 Jul 2025

Study reveals dopamine sends precise signals rather than broad brainwide messages

A new study from the University of Colorado Anschutz Medical Campus has upended decades of neuroscience dogma, revealing that dopamine, a neurotransmitter critical for movement, motivation, learning and mood, communicates in the brain with extraordinary precision, not broad diffusion as previously believed.

12 Jul 2025

Brain protein associated with aging not linked to youth contact sports

In recent years, some scientists and advocates have warned that playing contact sports like football and hockey may increase the risk of brain diseases like Alzheimer's disease or chronic traumatic encephalopathy (CTE) due to a buildup of a specific protein in the brain.

11 Jul 2025

Researchers create over 400 types of nerve cells from stem cells

Nerve cells are not just nerve cells. Depending on how finely we distinguish, there are several hundred to several thousand different types of nerve cell in the human brain according to the latest calculations.

11 Jul 2025

AI chatbots are not safe replacements for therapists, research says

Should AI chatbots replace your therapist? New research says "no." The new study exposes the dangerous flaws in using artificial intelligence (AI) chatbots for mental health support. For the first time, the researchers evaluated these AI systems against clinical standards for therapists.

8 Jul 2025

Restoring neuron balance in the amygdala reverses anxiety in mice

The Synaptic Physiology laboratory, led by Juan Lerma at the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and Miguel Hernández University (UMH) of Elche, has discovered that a specific group of neurons in the amygdala, a brain region involved in emotion regulation, plays a key role in the emergence of conditions such as anxiety, depression, and altered social behavior.

4 Jul 2025

New global guidelines aim to make clozapine safer and more accessible

The most effective antipsychotic drug for people with treatment-resistant schizophrenia is clozapine.

3 Jul 2025

Transforming OCD treatment through research and innovation

Obsessive-compulsive disorder (OCD) impacts approximately 2% of the global population, often preventing individuals from living life to their full potential.

2 Jul 2025

Many ADHD trials in adults lack proper diagnostic standards

Millions of adults around the world are diagnosed with ADHD every year, and there is a great need for research in the field.

1 Jul 2025

New study reveals how diverse brain cells unite to guide decisions

Every decision begins invisibly. Long before someone acts, the brain is already hard at work gathering evidence, weighing options, and gradually committing to a choice.

27 Jun 2025

TET1 identified as key regulator in cancer and chronic disease

Recent findings shed new light on the critical role of TET1, a pivotal player in epigenetic regulation, in the development and progression of various clinical diseases.

25 Jun 2025

Genetic markers show promise in predicting mood disorder treatment outcomes

In a comprehensive Genomic Press Thought Leaders Invited Review, researchers have synthesized findings from dozens of studies examining how genetic markers for mood disorders influence treatment outcomes and clinical features across major psychiatric conditions.

24 Jun 2025

Grammatical errors could aid in the early detection of schizophrenia

Meta-analysis shows syntax deficits in schizophrenia, emphasizing the role of language in diagnosis and the development of effective therapeutic strategies.

18 Jun 2025

Disrupted biological rhythms in teens can produce unexpected brain effects

A new McGill University-led study suggests that disrupting the body's internal clock during adolescence can alter how the brain responds to an in-utero risk factor linked to certain brain disorders.

17 Jun 2025

Popular painkiller use linked to gut microbiome shifts

Physical comorbidities from mental illness drive up hospital strain in Europe

A recent study led by Judit Simon from the Department of Health Economics, Center for Public Health, at the Medical University of Vienna shows for the first time comprehensively the extent to which people with mental disorders suffer from physical illnesses - and the resulting hospital costs.

11 Jun 2025

Weight loss drug semaglutide proven safe and effective for people with schizophrenia

Diabetic weight loss medications are effective for people with schizophrenia without affecting psychotic symptoms, University of Queensland researchers have found.

10 Jun 2025

Weekly risperidone capsule delivers consistent drug levels for schizophrenia patients

For many patients with schizophrenia, other psychiatric illnesses, or diseases such as hypertension and asthma, it can be difficult to take their medicine every day.

10 Jun 2025

Taking antipsychotic medications lowers crash risk for drivers with schizophrenia

Taking antipsychotic medications as prescribed lowers the risk of a car crash for drivers with schizophrenia, according to new research published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/lookup/doi/10.1503/cmaj.250020.

9 Jun 2025

Symptom provocation may boost effectiveness of repetitive transcranial magnetic stimulation

A new study in JAMA Psychiatry makes the case that symptom provocation may significantly improve the clinical effectiveness of repetitive transcranial magnetic stimulation (rTMS), a noninvasive brain stimulation method used to treat depression, obsessive-compulsive disorder (OCD) and nicotine dependence.

6 Jun 2025