Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

A lot of thought, little action: Proposals about mental health go unheeded

Thousands of people struggle to access mental health services in Florida. The treatment system is disjointed and complex.

22 Mar 2023

Investigating how gut microbiota affect neuroplasticity and neurodevelopment

In a recent study published in the journal Neuropharmacology, researchers in Pisa, Italy, explored how gut microbiota can influence neuroplasticity.

20 Mar 2023

Gut microbiomes and mental health: how do they interact?

A new study published in the journal Frontiers in Medicine reviewed recent literature on the link between gut microbiota, the brain, and neurological disorders.

19 Mar 2023

Two counties square off with California over mental health duties

Sacramento and Solano counties are in a standoff with the state over mental health coverage for a portion of Medicaid patients in those counties — a dispute that threatens to disrupt care for nearly 50,000 low-income residents receiving treatment for severe mental illness.

15 Mar 2023

A convergent coexpression approach identifies novel genes associated with autism

The current study analyzes transcriptional convergence across many autism risk genes.

14 Mar 2023

Study identifies link between oral and gut microbiomes and depression

Researchers investigate the role of the oral-gut-brain axis in anxiety and depression.

14 Mar 2023

Schizophrenia risk conferred by rare damaging genetic variants is conserved across ethnicities

Researchers have identified two previously unknown genes linked to schizophrenia and newly implicated a third gene as carrying risk for both schizophrenia and autism.

13 Mar 2023

Scientists study how maternal SARS-CoV-2 infection during pregnancy affects child’s brain development

Scientists led by the Lieber Institute for Brain Development are studying how a mother's SARS-CoV-2 infection during pregnancy affects the biology of the placenta and the corresponding trajectory of the child's brain development, including the risk for neurodevelopmental disorders such as schizophrenia and autism.

13 Mar 2023

Scientists design a model to track hippocampal synaptic plasticity

Scientific evidence shows how the cognitive decline in Alzheimer's disease (AD) is caused by the buildup of amyloid beta proteins, which promote synaptic malfunction.

9 Mar 2023

Researchers show how CBD can reduce seizures in treatment-resistant forms of childhood epilepsy

Researchers at Aston University have contributed to the discovery of a previously unknown way in which cannabidiol (CBD), a non-psychoactive component of cannabis, can reduce seizures in many treatment-resistant forms of childhood epilepsy.

6 Mar 2023

Women with schizophrenia have threefold risk of interpersonal violence during and after pregnancy

Pregnant and postpartum people with schizophrenia have a more than threefold increase in the risk of an emergency department visit for interpersonal violence, compared with those without schizophrenia, according to a new study in CMAJ.

6 Mar 2023

Augmenting an antidepressant with aripiprazole may help some older adults with treatment-resistant depression

For older adults with clinical depression that has not responded to standard treatments, adding the drug aripiprazole (brand name Abilify) to an antidepressant they're already taking is more effective than switching from one antidepressant to another, according to a new multicenter study led by Washington University School of Medicine in St. Louis.

3 Mar 2023