Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently from the general population.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Free-energy principle can explain how neural networks are optimized for efficiency

The RIKEN Center for Brain Science (CBS) in Japan, along with colleagues, has shown that the free-energy principle can explain how neural networks are optimized for efficiency.

16 Jan 2022

Study provides valuable insight into the developmental origins of schizophrenia

Scientists from Cardiff University have discovered new links between the breakdown in brain cell development and the risk of schizophrenia and other psychiatric disorders.

16 Jan 2022

Link between two key parts of the brain plays a role in neuropsychiatric brain disorders

Florida State University researchers have identified a link between two key parts of the brain that play significant roles in conditions such as Alzheimer's disease, post-traumatic stress disorder, schizophrenia and depression.

12 Jan 2022

Study offers new evidence on how childhood immunometabolic risk factors may lead to depression, psychosis

A growing body of research suggests that early-life infection, inflammation, and metabolic changes could contribute to psychiatric disorders – perhaps via effects during critical periods of brain development.

11 Jan 2022

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

In this interview, we spoke to Dr. Cynthia McMurray about her latest research into Alzheimer's disease.

11 Jan 2022

Study reinforces the link between microglia and some cases of brain disease

Certain subtle differences in DNA sequences are known to raise the chances a person may develop Alzheimer's or Parkinson's disease.

6 Jan 2022

New study targets the methylation profile of microglia from human brain

In the central nervous system, microglial cells play critical roles in development, aging, brain homeostasis, and pathology. Recent studies have shown variation in the gene-expression profile and phenotype of microglia across brain regions and between different age and disease states.

29 Dec 2021

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

There has been a remarkable increase in intake of simple sugar (sucrose, isomerized sugar (corn syrup)) from beverages and diets in modern society. The intake of simple sugars in adolescents in which mental disorders frequently occur is higher than any other generations.

28 Dec 2021

Recently evolved region of the ‘dark genome’ provides clues to treatment of schizophrenia, bipolar disorder

Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder.

23 Dec 2021

Star-shaped cells in the brain regulate cognitive flexibility

As we live in a dynamically changing environment, it is important for our brain to not only learn new things but also to modify existing memories.

21 Dec 2021

Study reveals how stigma has changed over two decades for mental health disorders

For the first time since national data have been tracked in the United States, stigma toward people with depression has dropped significantly, according to a study by Indiana University researchers.

21 Dec 2021

Deletion of autism-linked gene diminishes myelin in mice

Myelin, a sheath of insulation around nerves that enables electrical impulses to efficiently travel through the central nervous system, is diminished in mice that have a gene deletion associated with autism spectrum disorder, new research finds.

21 Dec 2021

Pandemic poses short- and long-term risks to babies, especially boys

The pandemic has created a hostile environment for pregnant people and their babies. Stress levels among expectant mothers have soared. Pregnant women with covid are five times as likely as uninfected pregnant people to require intensive care and 22 times as likely to die. Infected moms are four times as likely to have a stillborn child.

21 Dec 2021

Novel imaging method used to map glycosylation patterns linked with Alzheimer’s disease

Using new methodology, University of Kentucky researchers have mapped the variations in sugar chains attached to brain proteins from deceased healthy individuals or individuals with Alzheimer's disease.

15 Dec 2021

Researchers identify two new AMD drug candidates using a stem-cell-derived model

Using a stem-cell-derived model, researchers have identified two drug candidates that may slow dry age-related macular degeneration (AMD), a leading cause of blindness for which no treatment exists.

15 Dec 2021

Childhood trauma may increase the risk of psychotic symptoms in young cannabis users

Childhood trauma may increase the chance of young people experiencing psychotic symptoms when using cannabis, University of Queensland research has found.

14 Dec 2021

Adults with pathogenic copy number variants more likely to have poorer health, study suggests

Adults with specific genetic causes of mental health and other brain disorders had significantly higher rates of chronic disease and twice as many annual emergency room visits when compared to a control group without these genetic conditions, a Geisinger study found.

13 Dec 2021

Antipsychotic drugs associated with increase in risk of breast cancer

Researchers at Washington University School of Medicine in St. Louis have found that many commonly prescribed antipsychotic medications are associated with a significant increase in risk of breast cancer.

6 Dec 2021

Researchers discover clearest evidence to date of how memories form

In a discovery that could one day benefit people suffering from traumatic brain injury, Alzheimer's disease, and schizophrenia, UT Southwestern researchers have identified the characteristics of more than 100 memory-sensitive neurons that play a central role in how memories are recalled in the brain.

6 Dec 2021

Improving light availability can help normalize the altered sleep timing in people with schizophrenia

Disturbed sleep timing in people living with schizophrenia is more likely to be related to light exposure than to intrinsic biological factors.

2 Dec 2021

Schizophrenia

Overview

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Feature Articles

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Free-energy principle can explain how neural networks are optimized for efficiency

Study provides valuable insight into the developmental origins of schizophrenia

Link between two key parts of the brain plays a role in neuropsychiatric brain disorders

Study offers new evidence on how childhood immunometabolic risk factors may lead to depression, psychosis

Developing a 'fingerprint' test that could diagnose Alzheimer’s early

Study reinforces the link between microglia and some cases of brain disease

New study targets the methylation profile of microglia from human brain

Excessive intake of simple sugar in adolescents could be a risk factor of psychiatric disorders

Recently evolved region of the ‘dark genome’ provides clues to treatment of schizophrenia, bipolar disorder

Star-shaped cells in the brain regulate cognitive flexibility

Study reveals how stigma has changed over two decades for mental health disorders

Deletion of autism-linked gene diminishes myelin in mice

Pandemic poses short- and long-term risks to babies, especially boys

Novel imaging method used to map glycosylation patterns linked with Alzheimer’s disease

Researchers identify two new AMD drug candidates using a stem-cell-derived model

Childhood trauma may increase the risk of psychotic symptoms in young cannabis users

Adults with pathogenic copy number variants more likely to have poorer health, study suggests

Antipsychotic drugs associated with increase in risk of breast cancer

Researchers discover clearest evidence to date of how memories form

Improving light availability can help normalize the altered sleep timing in people with schizophrenia

Could heart rate be a risk factor for dementia?

Can meal times affect your risk of glucose intolerance?

How has COVID-19 Impacted our Economy?

Schizophrenia

Overview

Feature Articles

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

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