Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently to the general population. It is characterized by episodes of psychosis, usually with hallucinations or delusions.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Research reveals new genetic insights into how the brain folds

New research is helping unlock the mystery of how the brain folds as a baby develops in the womb - a process critical to healthy brain function.

1 Jul 2020

Researchers track brain receptor as it transmits or inhibits neural signals

For the first time, researchers in the lab of CSHL Professor Hiro Furukawa have been able to track each atom in the NMDA receptor, an important brain protein, as it transmits or inhibits neural signals. Critical for brain development and function, the receptor converts chemical messages between cells into electrical signals within a neuron.

30 Jun 2020

Study provides mechanistic explanation of psychotic symptoms in young people

Schizophrenia symptoms may be the result of increased connections between sensory and language-processing brain areas.

30 Jun 2020

Study identifies new gene variants tied to type-2 diabetes

After examining the genes of more than 200,000 people all over the world who have type-2 diabetes, researchers from the Perelman School of Medicine at the University of Pennsylvania and the Veterans Health Administration's Corporal Michael J. Crescenz Veterans Affairs Medical Center found hundreds of genetic variants never before linked to the disease.

23 Jun 2020

Mice study shows how oxytocin can amplify aggression as well as friendliness

During the pandemic lockdown, as couples have been forced to spend days and weeks in one another's company, some have found their love renewed while others are on their way to divorce court.

22 Jun 2020

Study analyzes the economic behavior of cocaine-dependent schizophrenia patients

A study conducted by Spanish and French universities analyzes the economic behavior of people with schizophrenia or antisocial personality disorder who also consume cocaine.

22 Jun 2020

Antipsychotic medications do not treat young people with early psychosis

Researchers at Orygen have found that some young people with early stage first episode psychosis (FEP) can experience reduced symptoms and improve functioning without antipsychotic medication when they are provided with psychological interventions and comprehensive case management.

17 Jun 2020

Oxytocin study may help treat a variety of psychiatric conditions

During the pandemic lockdown, as couples have been forced to spend days and weeks in one another's company, some have found their love renewed while others are on their way to divorce court.

16 Jun 2020

Researchers examine how neurons represent the direction of a moving object during self-motion

Our brains use various reference frames--also known as coordinate systems--to represent the motion of objects in a scene.

15 Jun 2020

Researchers identify two brain phenomena that may explain the side-effects of ketamine

Researchers have identified two brain phenomena that may explain some of the side-effects of ketamine.

11 Jun 2020

Examining dopamine receptors in their natural environment

Dopamine, a chemical that sends messages between different parts of the brain and body, plays a key role in a variety of diseases and behaviors by interacting with receptors on cells.

11 Jun 2020

NMDA receptors play key role in sleep deficits that accompany psychiatric disorders

Sofya Kulikova, a researcher at HSE University in Perm, is part of an international research team that has discovered potential mechanisms that explain the sleep spindle deficit in electroencephalograms (EEG) of people with schizophrenia. The article was published in the Schizophrenia Research on June 5.

5 Jun 2020

Cognitive behavior therapy superior to other psychotherapies at boosting the immune system

A review of 56 randomized clinical trials finds that psychological and behavioral therapies may be effective non-drug treatments for reducing disease-causing inflammation in the body.

3 Jun 2020

High prenatal choline levels may mitigate negative effects of COVID-19 on newborns

Pregnant women who take extra choline supplements may mitigate the negative impact that viral respiratory infections, including COVID-19, can have on their babies, according to a new study from researchers in the Departments of Psychiatry and Obstetrics and Gynecology at the University of Colorado Anschutz Medical Campus.

1 Jun 2020

Out-of-sync gamma waves in the brain may underlie learning issues in psychiatric disorders

A new UC San Francisco study has pinpointed a specific pattern of brain waves that underlies the ability to let go of old, irrelevant learned associations to make way for new updates.

1 Jun 2020

New book series brings updated reviews on diabetes and obesity

Frontiers in Clinical Drug Research - Diabetes and Obesity is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of two metabolic diseases - diabetes and obesity.

27 May 2020

Study paves way to better understand the pathophysiology of schizophrenia

There is an extremely high probability that individuals with 22q11.2 microdeletion syndrome - a rare genetic disorder - will develop schizophrenia together with one of its most common symptoms, auditory hallucinations.

26 May 2020

Can Chlorpromazine help treat COVID-19?

A new research paper published in the journal L'Encéphale in May 2020 reports on the planned ReCoVery Study, which will examine the possibility of repurposing the antipsychotic drug chlorpromazine for the treatment of COVID-19.

25 May 2020

GlobalData: Patients treated for ICU delirium will increase as COVID-19 outbreak continues

An estimated 70–80% of ventilated patients will experience ICU delirium, which causes patients to enter a confused state and can lead to long-term cognitive impairments and memory deficits. GlobalData, therefore, expects to see an increase in the administration of pharmacological treatments for ICU delirium as the COVID-19 outbreak continues.

22 May 2020