Schizophrenia

Schizophrenia is a chronic debilitating disorder which affects more than two million Americans, and millions more worldwide. While significant progress has been made in understanding the disease and developing treatments, there remains a significant unmet medical need. More than 50% of patients switch their medication in a given year due to either poor response or the experience of adverse events.

Schizophrenia

Schizophrenia is a chronic mental health disorder that causes people to think, feel and perceive the world differently to the general population. It is characterized by episodes of psychosis, usually with hallucinations or delusions.

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Study could lead to blood-based diagnostic test for schizophrenia

Scientists at Sanford Burnham Prebys have discovered how levels of a protein could be used in the future as a blood-based diagnostic aid for schizophrenia.

27 Jul 2021

Mayo Clinic study provides insights into risk factors for severe COVID-19 in younger populations

Using data from 9,859 COVID-19 infections, Mayo Clinic researchers have new insights into risk factors for younger populations, some of which differ significantly from their older counterparts.

20 Jul 2021

Study finds sex differences in astrocyte-mediated synaptic connectivity during brain development

During development, brain cells may find different ways to connect with each other based on sex, according to researchers at the Marshall University Joan C. Edwards School of Medicine.

19 Jul 2021

Study opens the door to improved treatment for psychosis sufferers

University of Otago scientists have opened the door to improved treatment of brain dysfunction which causes psychosis.

15 Jul 2021

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

Researchers at the Max Planck Florida Institute for Neuroscience have discovered that the cell adhesion protein IgSF11 determines the layer-specific synaptic connectivity of a distinct class of cortical interneurons.

15 Jul 2021

ADHD patients with a psychiatric comorbidity more likely to stop taking their ADHD medicine

A research study from the The Lundbeck Foundation Initiative for Integrative Psychiatric Research iPSYCH shows that people with ADHD, who also have another psychiatric diagnosis, are more likely to stop taking their ADHD medicine.

8 Jul 2021

Exploring links between stress, choline deficiency, preterm births, and mental illness

In two recent articles published in Schizophrenia Bulletin, Sharon Hunter, PhD, an associate professor in the University of Colorado School of Medicine Department of Psychiatry, and M. Camille Hoffman, MD, MSc, an associate professor in the University of Colorado School of Medicine Department of Obstetrics and Gynecology, along with their research group, have uncovered a potential link between choline deficiency in Black pregnant women in the United States and increased risk of developmental and behavioral issues that can evolve into mental illness later in their children's lives.

7 Jul 2021

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

From the bark of a puppy to the patter of rain against the window, our brains receive countless signals every second. Most of the time, we tune out inconsequential cues--the buzz of a fly, the soft rustle of leaves in the tree--and pay attention to important ones--the sound of a car horn, a bang on the door.

7 Jul 2021

22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia

Researchers from Skoltech and the Mental Health Research Center have found 22 lipids in the blood plasma of people with schizophrenia that were associated with lower symptom improvement over time during treatment.

6 Jul 2021

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Methylglyoxal (MG) is a highly reactive α-ketoaldehyde formed endogenously as a byproduct of the glycolytic pathway. MG accumulates under conditions of hyperglycemia, impaired glucose metabolism, or oxidative stress.

2 Jul 2021

Study offers a new model for examining genetic risk associated with nicotine dependence

Some people casually smoke cigarettes for a while and then stop without a problem, while others develop long-term, several packs-per-day habits. A complex mix of environmental, behavioral, and genetic factors appear to raise this risk for nicotine dependence.

1 Jul 2021

Scientists identify abnormal neural replay of memories in people with schizophrenia

Neuroscientists at UCL have, for the first time, identified abnormalities in the way memories are 'replayed' in the brains of people with schizophrenia; researchers say the pathbreaking study provides an entirely new basis for explaining many of the condition's core symptoms.

30 Jun 2021

Study uncovers common neural mechanism for cognitive impairment in autism and schizophrenia

Many neurodevelopmental disorders share similar symptoms, such as learning disabilities or attention deficits.

30 Jun 2021

New analysis links distinct patterns of genetic mutations with OCD

In the first analysis of its kind, researchers at Columbia University Vagelos College of Physicians and Surgeons and several other institutions have linked distinct patterns of genetic mutations with obsessive-compulsive disorder (OCD) in humans.

28 Jun 2021

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Oncotarget published "The presence of polymorphisms in genes controlling neurotransmitter metabolism and disease prognosis in patients with prostate cancer: a possible link with schizophrenia" reported that polymorphisms of neurotransmitter metabolism genes were studied in patients with prostate cancer (PC) characterized by either reduced or extended serum prostate-specific antigen doubling time corresponding to unfavorable and favorable disease prognosis respectively.

28 Jun 2021

Study shows how loss of glial protein drives brain development dysfunction

When we think of the brain, we think of neurons. But much of the brain is made of non-neuronal cells called glial cells, which help regulate brain development and function.

25 Jun 2021

New project aims to identify quantitative biological features common across diseases

Building on the success of innovative research by the PRISM project, the Innovative Medicine Initiative 2, a joint undertaking between the EU and the European Federation of Pharmaceutical Industries and Associations (EFPIA), has backed the program with funding for a new project to explore the underlying biology of Alzheimer's disease, schizophrenia and Major Depressive Disorder (MDD).

23 Jun 2021

Schizophrenia

Overview

Schizophrenia Diagnosis

Schizophrenia Causes

Schizophrenia Signs and Symptoms

Feature Articles

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

Study could lead to blood-based diagnostic test for schizophrenia

Mayo Clinic study provides insights into risk factors for severe COVID-19 in younger populations

Study finds sex differences in astrocyte-mediated synaptic connectivity during brain development

Study opens the door to improved treatment for psychosis sufferers

Research sheds light on a new mechanism for inhibitory synapse specificity in the cortex

ADHD patients with a psychiatric comorbidity more likely to stop taking their ADHD medicine

Exploring links between stress, choline deficiency, preterm births, and mental illness

Study identifies specialized immune cells that sculpt inhibitory neurons to regulate brain wiring

22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia

Methylglyoxal detoxification deficits can be involved in the development of schizophrenia

Study offers a new model for examining genetic risk associated with nicotine dependence

Scientists identify abnormal neural replay of memories in people with schizophrenia

Study uncovers common neural mechanism for cognitive impairment in autism and schizophrenia

New analysis links distinct patterns of genetic mutations with OCD

Study explores the potential role of gene polymorphisms in pathogenesis of prostate cancer

Study shows how loss of glial protein drives brain development dysfunction

New project aims to identify quantitative biological features common across diseases

Proven treatment for psychosis has been recognized as standard of care

Immune system dysfunction can alter the link between cannabis use and psychosis

New AI software shows promise to prevent relapse of severe mental illness

Increasing your risk of IBD through processed food

World Brain Day 2021: An interview with Professor Alan Thompson

Preventing lethal blood clots

Schizophrenia

Overview

Feature Articles

Schizophrenia Neural Processes

Schizophrenia Mechanisms

Schizophrenia Screening, Prevention and Management

Schizophrenia Medication

Schizophrenia Interventions

Schizophrenia Prognosis

Latest Schizophrenia News and Research

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