Schizophrenia News and Research

Latest Schizophrenia News and Research

Low pre-morbid IQ not associated with psychosis risk

The strong correlations currently observed between low IQ and risk for psychosis are most likely linked to the influence that psychosis onset has on cognitive functioning rather than a shared genetic background, suggest study findings.

7 Jun 2012

Pathophysiologic differences evident between schizophrenia, bipolar

Review findings reveal differences in the pathophysiology of bipolar disorder and schizophrenia, relating specifically to the medial temporal lobe and associated limbic regions.

7 Jun 2012

BioLineRx receives two U.S. patent allowances for BL-1021 to treat neuropathic pain

BioLineRx, a biopharmaceutical development company, announced today that two Notices of Allowance have been issued by the United States Patent and Trademark Office (USPTO) for BL-1021, an orally available small molecule for treating neuropathic pain.

6 Jun 2012

UCSD researchers receive $4M NIMH grant to study accelerated biological aging in schizophrenia

Researchers at the Stein Institute for Research on Aging at the University of California, San Diego have received a $4 million grant from the National Institute of Mental Health (NIMH), part of the National Institutes of Health, to study accelerated biological aging in schizophrenia.

6 Jun 2012

Scientists discover previously unrecognized signaling network disrupted in lung cancer

A team of researchers led by Dr. Goutham Narla at Case Western Reserve University School of Medicine in collaboration with scientists at Mount Sinai School of Medicine in New York, have discovered a previously unrecognized signaling network disrupted in lung cancer that can be turned back on by a novel combination of two previously approved FDA drugs.

2 Jun 2012

Subtle executive impairments indicate familial schizophrenia risk

The unaffected first-degree relatives of patients with schizophrenia show subtle executive function impairments, and these deficits are associated with negative symptoms, investigators report.

1 Jun 2012

Feds announce effort to slash inappropriate use of antipsychotic drugs in nursing homes

An estimated 40 percent of nursing home residents with dementia receive the drugs, which are approved to treat schizophrenia and bipolar disorder.

1 Jun 2012

Over half of FEP patients achieve symptomatic remission

More than half of patients with a first episode of psychosis achieve symptomatic remission after 2 years of treatment, but recovery rates are lower, results from a Singaporean study show.

31 May 2012

New method can solve 3-D structures of integral membrane proteins

A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods.

31 May 2012

Topline results from Alkermes’ ALKS 37 phase 2b study on opioid-induced constipation

Alkermes plc today announced topline results from a phase 2b dose-ranging clinical study of ALKS 37 in the treatment of opioid-induced constipation. The multicenter, randomized, double-blind, placebo-controlled, repeat-dose study was designed to assess the safety, tolerability, pharmacokinetic profile and efficacy of ALKS 37 in approximately 150 patients.

31 May 2012

Transcranial stimulation technique reduces hallucinations

Transcranial direct-current stimulation is effective for the treatment of auditory hallucinations in patients with schizophrenia, study results show.

30 May 2012

Patients with mental health issues overwhelm ERs

Patients suffering from schizophrenia, psychotic tendencies and suicidal behaviors are burdening hospital ERs, reports Modern Healthcare.

30 May 2012

Positive results from Alkermes’ ALKS 5461 phase 1/2 study on MDD

Alkermes plc today presented positive results from the phase 1/2 study of ALKS 5461, a novel drug compound for major depressive disorder (MDD) in patients who have an inadequate response to standard therapies for clinical depression, in an oral session at the 52nd Annual New Clinical Drug Evaluation Unit (NCDEU) Meeting in Phoenix.

30 May 2012

PERK protein necessary to maintain behavioral flexibility

Researchers have identified a protein necessary to maintain behavioral flexibility, which allows us to modify our behaviors to adjust to circumstances that are similar, but not identical, to previous experiences. Their findings, which appear in the journal Cell Reports, may offer new insights into addressing autism and schizophrenia—afflictions marked by impaired behavioral flexibility.

25 May 2012

Brain cells prune circuits in the brain by eating away excess synapses

We’re born with our brains prewired, but as information comes in from our environment, this circuitry is updated. A study from Boston Children’s Hospital provides a new glimpse of how this happens: Brain cells known as microglia, tuned into the crosstalk between neurons, literally engulf unnecessary connections, known as synapses, and prune them away.

24 May 2012

State roundup: Labor unions continue Wis. Governor recall push; 'Affordability gap' in Minn.

Democrats and unions hoping to turn Wisconsin Governor Scott Walker out of office over his efforts to tame the power of organized labor are finding it tough going with only two weeks to go before a historic recall election. … Walker pushed through the legislature a law requiring public sector union members to pay part of the cost of health insurance and pensions, limited pay rises, made paying union dues voluntary and forced unions to be recertified every year.

24 May 2012

CHDI, Lundbeck enter collaboration to investigate targeted therapy for Huntington's disease

CHDI Foundation, Inc. and Lundbeck today announced a research collaboration to investigate a targeted therapy for Huntington's disease (HD). Currently, no treatment exists to slow or halt the progression of HD, a challenging hereditary neurodegenerative disease characterized by a triad of behavioral, cognitive, and motor symptoms.

21 May 2012

Large survey of genetic variation offers insights into human diseases

A large survey of human genetic variation, published today in the online version of the journal Science, shows that rare genetic variants are not so rare after all and offers insights into human diseases.

19 May 2012

Researchers identify novel base modification in RNA

Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases.

18 May 2012

Scientists, students share latest innovations in mental health at 13th Annual Research Half Day

Today, local scientists and students are sharing leading research in mental health. The 13th Annual Research Half Day, hosted by Lawson Health Research Institute and St. Joseph's Health Care London's Regional Mental Health Care (RMHC) London and St. Thomas, will present science that could change the course of patient care.

17 May 2012

Schizophrenia News and Research

Latest Schizophrenia News and Research

Low pre-morbid IQ not associated with psychosis risk

Pathophysiologic differences evident between schizophrenia, bipolar

BioLineRx receives two U.S. patent allowances for BL-1021 to treat neuropathic pain

UCSD researchers receive $4M NIMH grant to study accelerated biological aging in schizophrenia

Scientists discover previously unrecognized signaling network disrupted in lung cancer

Subtle executive impairments indicate familial schizophrenia risk

Feds announce effort to slash inappropriate use of antipsychotic drugs in nursing homes

Over half of FEP patients achieve symptomatic remission

New method can solve 3-D structures of integral membrane proteins

Topline results from Alkermes’ ALKS 37 phase 2b study on opioid-induced constipation

Transcranial stimulation technique reduces hallucinations

Patients with mental health issues overwhelm ERs

Positive results from Alkermes’ ALKS 5461 phase 1/2 study on MDD

PERK protein necessary to maintain behavioral flexibility

Brain cells prune circuits in the brain by eating away excess synapses

State roundup: Labor unions continue Wis. Governor recall push; 'Affordability gap' in Minn.

CHDI, Lundbeck enter collaboration to investigate targeted therapy for Huntington's disease

Large survey of genetic variation offers insights into human diseases

Researchers identify novel base modification in RNA

Scientists, students share latest innovations in mental health at 13th Annual Research Half Day

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Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

Schizophrenia News and Research

Latest Schizophrenia News and Research

Unlocking live single-cell functional insights

Fluidics in Modern Healthcare & Medical Device Innovation

How microRNA is transforming science: From discovery to diagnostics

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