Schizophrenia News and Research

Latest Schizophrenia News and Research

Subtle executive impairments indicate familial schizophrenia risk

The unaffected first-degree relatives of patients with schizophrenia show subtle executive function impairments, and these deficits are associated with negative symptoms, investigators report.

1 Jun 2012

Feds announce effort to slash inappropriate use of antipsychotic drugs in nursing homes

An estimated 40 percent of nursing home residents with dementia receive the drugs, which are approved to treat schizophrenia and bipolar disorder.

1 Jun 2012

Over half of FEP patients achieve symptomatic remission

More than half of patients with a first episode of psychosis achieve symptomatic remission after 2 years of treatment, but recovery rates are lower, results from a Singaporean study show.

31 May 2012

New method can solve 3-D structures of integral membrane proteins

A new method for rapidly solving the three-dimensional structures of a special group of proteins, known as integral membrane proteins, may speed drug discovery by providing scientists with precise targets for new therapies, according to a paper published May 20 in Nature Methods.

31 May 2012

Topline results from Alkermes’ ALKS 37 phase 2b study on opioid-induced constipation

Alkermes plc today announced topline results from a phase 2b dose-ranging clinical study of ALKS 37 in the treatment of opioid-induced constipation. The multicenter, randomized, double-blind, placebo-controlled, repeat-dose study was designed to assess the safety, tolerability, pharmacokinetic profile and efficacy of ALKS 37 in approximately 150 patients.

31 May 2012

Transcranial stimulation technique reduces hallucinations

Transcranial direct-current stimulation is effective for the treatment of auditory hallucinations in patients with schizophrenia, study results show.

30 May 2012

Patients with mental health issues overwhelm ERs

Patients suffering from schizophrenia, psychotic tendencies and suicidal behaviors are burdening hospital ERs, reports Modern Healthcare.

30 May 2012

Positive results from Alkermes’ ALKS 5461 phase 1/2 study on MDD

Alkermes plc today presented positive results from the phase 1/2 study of ALKS 5461, a novel drug compound for major depressive disorder (MDD) in patients who have an inadequate response to standard therapies for clinical depression, in an oral session at the 52nd Annual New Clinical Drug Evaluation Unit (NCDEU) Meeting in Phoenix.

30 May 2012

PERK protein necessary to maintain behavioral flexibility

Researchers have identified a protein necessary to maintain behavioral flexibility, which allows us to modify our behaviors to adjust to circumstances that are similar, but not identical, to previous experiences. Their findings, which appear in the journal Cell Reports, may offer new insights into addressing autism and schizophrenia—afflictions marked by impaired behavioral flexibility.

25 May 2012

Brain cells prune circuits in the brain by eating away excess synapses

We’re born with our brains prewired, but as information comes in from our environment, this circuitry is updated. A study from Boston Children’s Hospital provides a new glimpse of how this happens: Brain cells known as microglia, tuned into the crosstalk between neurons, literally engulf unnecessary connections, known as synapses, and prune them away.

24 May 2012

State roundup: Labor unions continue Wis. Governor recall push; 'Affordability gap' in Minn.

Democrats and unions hoping to turn Wisconsin Governor Scott Walker out of office over his efforts to tame the power of organized labor are finding it tough going with only two weeks to go before a historic recall election. … Walker pushed through the legislature a law requiring public sector union members to pay part of the cost of health insurance and pensions, limited pay rises, made paying union dues voluntary and forced unions to be recertified every year.

24 May 2012

CHDI, Lundbeck enter collaboration to investigate targeted therapy for Huntington's disease

CHDI Foundation, Inc. and Lundbeck today announced a research collaboration to investigate a targeted therapy for Huntington's disease (HD). Currently, no treatment exists to slow or halt the progression of HD, a challenging hereditary neurodegenerative disease characterized by a triad of behavioral, cognitive, and motor symptoms.

21 May 2012

Large survey of genetic variation offers insights into human diseases

A large survey of human genetic variation, published today in the online version of the journal Science, shows that rare genetic variants are not so rare after all and offers insights into human diseases.

19 May 2012

Researchers identify novel base modification in RNA

Over the past decade, research in the field of epigenetics has revealed that chemically modified bases are abundant components of the human genome and has forced us to abandon the notion we've had since high school genetics that DNA consists of only four bases.

18 May 2012

Scientists, students share latest innovations in mental health at 13th Annual Research Half Day

Today, local scientists and students are sharing leading research in mental health. The 13th Annual Research Half Day, hosted by Lawson Health Research Institute and St. Joseph's Health Care London's Regional Mental Health Care (RMHC) London and St. Thomas, will present science that could change the course of patient care.

17 May 2012

Nine fine-grained patterns of Internet usage may indicate depression

In a new study analyzing Internet usage among college students, researchers at Missouri University of Science and Technology have found that students who show signs of depression tend to use the Internet differently than those who show no symptoms of depression.

17 May 2012

Scientists identify and prioritize genes associated with schizophrenia

An Indiana University-led research team, along with a group of national and international collaborators, has identified and prioritized a comprehensive group of genes most associated with schizophrenia that together can generate a score indicating whether an individual is at higher or lower risk of developing the disease.

16 May 2012

Reducing off-label antipsychotic use may generate savings with little impact on patient care

Reducing the non-FDA-approved use of antipsychotic drugs may be a way to save money while having little effect on patient care, according to a Penn State College of Medicine study.

16 May 2012

Researchers develop new form of specially bred mouse that mimics ADHD

The number of attention deficit hyperactivity disorder (ADHD) cases in the United States are exploding. According to a 2011 statement by the Centers for Disease Control and Prevention, nearly one in 10 American children is diagnosed with the disorder.

11 May 2012

Maternal gluten sensitivity may increase risk of schizophrenia in children

Babies born to women with sensitivity to gluten appear to be at increased risk for certain psychiatric disorders later in life, according to research by scientists at Karolinska Institutet in Sweden and Johns Hopkins Children's Center in Baltimore.

11 May 2012

Schizophrenia News and Research

Latest Schizophrenia News and Research

Subtle executive impairments indicate familial schizophrenia risk

Feds announce effort to slash inappropriate use of antipsychotic drugs in nursing homes

Over half of FEP patients achieve symptomatic remission

New method can solve 3-D structures of integral membrane proteins

Topline results from Alkermes’ ALKS 37 phase 2b study on opioid-induced constipation

Transcranial stimulation technique reduces hallucinations

Patients with mental health issues overwhelm ERs

Positive results from Alkermes’ ALKS 5461 phase 1/2 study on MDD

PERK protein necessary to maintain behavioral flexibility

Brain cells prune circuits in the brain by eating away excess synapses

State roundup: Labor unions continue Wis. Governor recall push; 'Affordability gap' in Minn.

CHDI, Lundbeck enter collaboration to investigate targeted therapy for Huntington's disease

Large survey of genetic variation offers insights into human diseases

Researchers identify novel base modification in RNA

Scientists, students share latest innovations in mental health at 13th Annual Research Half Day

Nine fine-grained patterns of Internet usage may indicate depression

Scientists identify and prioritize genes associated with schizophrenia

Reducing off-label antipsychotic use may generate savings with little impact on patient care

Researchers develop new form of specially bred mouse that mimics ADHD

Maternal gluten sensitivity may increase risk of schizophrenia in children

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

Schizophrenia News and Research

Latest Schizophrenia News and Research

The future of automation: Machine learning–driven hepatocyte and organoid counting

From street to lab: Advancing controlled substance testing with handheld Raman and FTIR

Reimagining light scattering for biotherapeutics

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