T Cell News and Research

Latest T Cell News and Research

Fenofibrate benefits in diabetic retinopathy mediated through PPARα

Peroxisome proliferator–activated receptor α exerts protective effects on retinal pericytes, shows research that explains why fenofibrate is protective against diabetic retinopathy.

1 Dec 2014

Exome sequencing refines 46,XY DSD diagnosis

Exome sequencing can identify a likely genetic cause of 46,XY disorders of sex development in about a third of cases, report researchers.

1 Dec 2014

MD Anderson professor receives 13th annual City of Florence Prize in Molecular Sciences

Peter Friedl, M.D., Ph.D., professor of genitourinary medical oncology at The University of Texas MD Anderson Cancer Center, has received one of Italy's top scientific awards for his work in imaging and cancer growth, metastasis and therapy response.

1 Dec 2014

Promising new therapeutic strategy for chronic kidney disease

Chronic kidney disease (CKD) affects at least one in four Americans who are older than 60 and can significantly shorten lifespan. Yet the few available drugs for CKD can only modestly delay the disease's progress towards kidney failure. Now, however, a team led by researchers at the Perelman School of Medicine at the University of Pennsylvania, has found an aspect of CKD's development that points to a promising new therapeutic strategy.

1 Dec 2014

New book explores convergence as key to stable global agricultural platform

A scientific text, Convergence of Food Security, Energy Security and Sustainable Agriculture, is now available through Springer Science+Business Media.

1 Dec 2014

EMA accepts new IMBRUVICA (ibrutinib) application for treatment of Waldenstrom's macroglobulinemia

Pharmacyclics, Inc.today announced the acceptance of a Type II variation application for IMBRUVICA (ibrutinib) by the European Medicines Agency.

1 Dec 2014

CTI BioPharma announces upcoming presentations of pacritinib data at ASH Annual Meeting

CTI BioPharma Corp. (CTI) today announced the upcoming presentations of data highlighting pacritinib, an oral multikinase inhibitor with dual activity against JAK2 and FLT3, and tosedostat, an oral selective inhibitor of aminopeptidases, at the 56th American Society of Hematology (ASH) Annual Meeting and Exposition, being held December 6-9 in San Francisco, CA.

1 Dec 2014

CCR5 receptor plays key role in driving prostate cancer metastases

Although prostate cancer can be successfully treated in many men, when the disease metastasizes to the bone, it is eventually lethal. In a study published online December 1st in the journal Cancer Research, researchers show that the receptor CCR5 best known for its role in HIV therapy, may also be involved in driving the spread of prostate cancer to the bone.

1 Dec 2014

New vaccine shows promise in patients with metastatic breast cancer

A breast cancer vaccine developed at Washington University School of Medicine in St. Louis is safe in patients with metastatic breast cancer, results of an early clinical trial indicate. Preliminary evidence also suggests that the vaccine primed the patients' immune systems to attack tumor cells and helped slow the cancer's progression.

1 Dec 2014

Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

One of the main obstacles to finding effective therapies for human diseases has been our limited understanding of disease pathogenesis: we lack detailed knowledge of the cellular and molecular mechanisms that lead to the development of disease.

30 Nov 2014

Canadian Blood Services urges Canadians to support fundraising campaign

On "Giving Tuesday," Dec. 2, Canadian Blood Services is encouraging Canadians to help build a national public cord blood bank by making a financial donation to the $12.5 million For All Canadians fundraising campaign.

29 Nov 2014

Researchers use mathematical models to predict how immune cells respond to disease

Walter and Eliza Hall Institute researchers have defined for the first time how the size of the immune response is controlled, using mathematical models to predict how powerfully immune cells respond to infection and disease.

28 Nov 2014

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

A promising experimental immunotherapy drug works best in patients whose immune defenses initially rally to attack the cancer but then are stymied by a molecular brake that shuts down the response, according to a new study led by researchers at Dana-Farber Cancer Institute and the Yale University School of Medicine.

28 Nov 2014

Finding could upend scientific consensus about when embryonic cells begin separating into cell types

Bioengineers at the University of California, San Diego have discovered that mouse embryos are contemplating their cellular fates in the earliest stages after fertilization when the embryo has only two to four cells, a discovery that could upend the scientific consensus about when embryonic cells begin differentiating into cell types.

28 Nov 2014

UCL research opens up new way to treat neurological disorders

The way that tetanus neurotoxin enters nerve cells has been discovered by UCL scientists, who showed that this process can be blocked, offering a potential therapeutic intervention for tetanus. This newly-discovered pathway could be exploited to deliver therapies to the nervous system, opening up a whole new way to treat neurological disorders such as motor neuron disease and peripheral neuropathies.

28 Nov 2014

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

People affected by a common inherited form of autism could be helped by a drug that is being tested as a treatment for cancer.

27 Nov 2014

Researchers identify mechanism linked to brain damage

Researchers have discovered a mechanism linked to the brain damage often suffered by stroke victims--and are now searching for drugs to block it.

27 Nov 2014

Canada's current vitamin D intake recommendations need to be re-evaluated: Study

New research finds that current national vitamin D intake recommendations are too low and that body weight must be taken into account to determine the appropriate vitamin D dose in any given individual. This is currently not the case, posing a serious Canadian public health issue with significant cost and health impacts.

27 Nov 2014

Astronaut Koichi Wakata carried out live cell experiments with Leica Microsystems’ inverted research microscope

Astronaut Koichi Wakata of the Japan Aerospace Exploration Agency (JAXA) studied the effect of microgravity on bone density as well as on plants building their shape during his stay in the International Space Station (ISS) with an inverted research microscope by Leica Microsystems, the Leica DMI6000 B. He returned to earth with new data from several experiments at the ISS module "Kibo" which will now be evaluated and analyzed by him and collaborating scientists at Japanese research institutions.

From Leica Microsystems GmbH 27 Nov 2014

Ebola vaccine shows promising results in human trial

An experimental vaccine against the Ebola virus has proved effective and well-tolerated in the first human trial of a candidate Ebola drug.

27 Nov 2014

T Cell News and Research

Latest T Cell News and Research

Fenofibrate benefits in diabetic retinopathy mediated through PPARα

Exome sequencing refines 46,XY DSD diagnosis

MD Anderson professor receives 13th annual City of Florence Prize in Molecular Sciences

Promising new therapeutic strategy for chronic kidney disease

New book explores convergence as key to stable global agricultural platform

EMA accepts new IMBRUVICA (ibrutinib) application for treatment of Waldenstrom's macroglobulinemia

CTI BioPharma announces upcoming presentations of pacritinib data at ASH Annual Meeting

CCR5 receptor plays key role in driving prostate cancer metastases

New vaccine shows promise in patients with metastatic breast cancer

Phenotyping human diseases in mice: an interview with Professor Carola Vinuesa

Canadian Blood Services urges Canadians to support fundraising campaign

Researchers use mathematical models to predict how immune cells respond to disease

Experimental drug works best when patients' immune cells surrounding tumors express PD-L1

Finding could upend scientific consensus about when embryonic cells begin separating into cell types

UCL research opens up new way to treat neurological disorders

Researchers identify key molecule that drives excess protein production in Fragile X patients' brain

Researchers identify mechanism linked to brain damage

Canada's current vitamin D intake recommendations need to be re-evaluated: Study

Astronaut Koichi Wakata carried out live cell experiments with Leica Microsystems’ inverted research microscope

Ebola vaccine shows promising results in human trial

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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