T Cell News and Research

Latest T Cell News and Research

Dacomitinib ‘not superior’ to erlotinib in advanced NSCLC

Dacomitinib, an irreversible, pan-epidermal growth factor receptor tyrosine kinase inhibitor, does not improve outcomes compared with the first-generation EGFR–TKI erlotinib in patients with advanced non-small-cell lung cancer, irrespective of their KRAS mutation status, finds the ARCHER 1009 study.

24 Nov 2014

Researchers take major step in fight against sleeping sickness

Researchers from Aarhus University have taken an important step in the fight against sleeping sickness, a disease that is a major problem in parts of Africa. According to the World Health Organization, the disease threatens approximately 60 million people and the treatment options are poor.

24 Nov 2014

Scientists discover that brown fat could be used to manage type 2 diabetes

Scientists from Monash University and Stockholm University have discovered that brown fat, nicknamed the 'good fat' because it warms up the body in cold temperatures, burning up calories in the process, also 'hoovers up' excess sugar.

24 Nov 2014

New cell therapy offers hope for patients with liver cirrhosis

Liver disease patients could be helped by a new cell therapy to treat the condition.

24 Nov 2014

Raising awareness of sickle cell disease risks

Members of the public in sub-Saharan Africa who are carriers of the hereditary disease sickle cell disease must be educated aggressively through public health campaigns to raise awareness of the risks of parenting offspring with the disease if their partner is also a carrier, according to research published in the International Journal of Medical Engineering and Informatics.

24 Nov 2014

Authors review current progress in developing transgenic pig models for human diseases

Genetically engineered pigs, minipigs, and microminipigs are valuable tools for biomedical research, as their lifespan, anatomy, physiology, genetic make-up, and disease mechanisms are more similar to humans than the rodent models typically used in drug discovery research.

24 Nov 2014

Five USF faculty members named AAAS Fellow

Five faculty members from the University of South Florida in Tampa have been named Fellows of the American Association for the Advancement of Science. Election as an AAAS Fellow is an honor bestowed upon AAAS members by their peers.

24 Nov 2014

Abnormal connections between neurons cause motor coordination issues in autism

Abnormal connections between neurons are the likely cause of motor coordination issues seen in autism spectrum disorder. Using a mouse model of autism, scientists from the University of Chicago identified a malfunctioning neural circuit associated with reduced capacity for motor learning. This appears to arise from an inability to eliminate unneeded neural connections in the brain.

24 Nov 2014

Researchers make significant breakthrough for sufferers of bone disease

Researchers in bone tissue regeneration believe they have made a significant breakthrough for sufferers of bone trauma, disease or defects such as osteoporosis.

24 Nov 2014

Research: HD-IL2 can be effective in mRCC patients pre-treated with VEGF-targeted agents

High-dose interleukin-2 can be effective in selected metastatic renal cell cancer patients pre-treated with VEGF-targeted agents, reveals research presented today at the ESMO Symposium on Immuno-Oncology in Geneva, Switzerland.

24 Nov 2014

NUS researchers make breakthrough discovery that could lead to future treatment for multiple sclerosis

A multi-disciplinary research team from the National University of Singapore has made a breakthrough discovery of a new type of immune cells that may help in the development of a future treatment for multiple sclerosis (MS).

24 Nov 2014

NOS1AP gene may help explain biological process of schizophrenia

A gene associated with schizophrenia plays a role in brain development and may help to explain the biological process of the disease, according to new Rutgers research.

24 Nov 2014

Study identifies H3.3 protein as key regulator in cellular senescence

Changes to the structure of the protein histone H3.3 may play a key role in silencing genes that regulate cancer cell growth, according to a study led by researchers from the Icahn School of Medicine at Mount Sinai and published online this month in the journal Nature Communications.

23 Nov 2014

Unique ability helps prolific bacterium to afflict humans, animals and even plants

New research has found that one of the world's most prolific bacteria manages to afflict humans, animals and even plants by way of a mechanism not before seen in any infectious microorganism -- a sense of touch. This unique ability helps make the bacteria Pseudomonas aeruginosa ubiquitous, but it also might leave these antibiotic-resistant organisms vulnerable to a new form of treatment.

23 Nov 2014

Researchers identify way to improve memory by manipulating molecule linked to Alzheimer's

In a new study conducted by the Sagol Department of Neurobiology at the University of Haifa and published recently in the Journal of Neuroscience, researchers report that they've found a way to improve memory by manipulating a specific molecule that is known to function poorly in old age and is closely linked to Alzheimer's disease.

23 Nov 2014

Research shows that immune checkpoint inhibitors may work in glioblastoma, brain metastases

New evidence that immune checkpoint inhibitors may work in glioblastoma and brain metastases was presented today by Dr Anna Sophie Berghoff at the ESMO Symposium on Immuno-Oncology 2014 in Geneva, Switzerland.

23 Nov 2014

UCLA creates largest-ever protein that self-assembles into molecular 'cage'

UCLA biochemists have created the largest-ever protein that self-assembles into a molecular "cage." The research could lead to synthetic vaccines that protect people from the flu, HIV and other diseases.

23 Nov 2014

Researchers examine genomic landscapes of humans and mice

Looking across evolutionary time and the genomic landscapes of humans and mice, an international group of researchers has found powerful clues to why certain processes and systems in the mouse - such as the immune system, metabolism and stress response - are so different from those in people. Building on years of mouse and gene regulation studies, they have developed a resource that can help scientists better understand how similarities and differences between mice and humans are written in their genomes.

23 Nov 2014

Hydroxyurea therapy offers safe, effective disease management of SCA

Conclusive data show that hydroxyurea therapy offers safe and effective disease management of sickle cell anemia (SCA) and reduces the risk of stroke, prompting early termination by the National Heart Lung and Blood Institute of a key clinical trial studying the drug's efficacy.

23 Nov 2014

New drug shows promise against treatment-resistant non-small cell lung cancer

A new drug that targets not only common cancer-causing genetic mutations in patients with non-small cell lung cancer (NSCLC), but also a form of the mutation that causes resistance to treatment, has shown promising results in patients in a phase I/II clinical trial.

23 Nov 2014