T Cell News and Research

Latest T Cell News and Research

Incyte enters into clinical trial collaboration agreement with Merck to evaluate safety of IDO1 inhibitor

Incyte Corporation (Nasdaq: INCY) announced today that it has entered into a clinical trial collaboration agreement with Merck, through a Merck subsidiary, to evaluate the safety and efficacy of Incyte's oral indoleamine dioxygenase-1 (IDO1) inhibitor, INCB24360, and Merck's investigational anti-PD-1 immunotherapy, MK-3475, in a Phase I/II study in previously treated metastatic and recurrent non-small cell lung cancer (NSCLC), and other advanced or metastatic cancers.

5 Feb 2014

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Pfizer Inc. announced today that it has agreed with Merck & Co., Inc., known as MSD outside the United States and Canada ("Merck"), through two Merck subsidiaries, to explore the therapeutic potential of Merck's investigational anti-PD-1 therapy, MK-3475, in combination with two Pfizer oncology assets.

5 Feb 2014

Bioengineer receives $1.4M grant to create nanoparticle system to shore up arterial walls

A UT Arlington bioengineer has received a four-year, $1.4 million National Institutes of Health grant to create a nanoparticle system to shore up arterial walls following angioplasty and stenting procedures to treat coronary arterial disease.

5 Feb 2014

Scientists engineered microchip coated with blood vessel cells to study cardiovascular nanomedicine

Designing nanomedicine to combat diseases is a hot area of scientific research, primarily for treating cancer, but very little is known in the context of atherosclerotic disease.

5 Feb 2014

Findings expand treatment options for hormone-dependent breast cancer

According to the United States Centers for Disease Control and Prevention, breast cancer is the most common cancer in women. For patients whose breast cancers are hormone-dependent, current treatment focuses on using drugs that block estrogen (a type of hormone) from attaching to estrogen receptors on tumor cells to prevent the cells from growing and spreading.

5 Feb 2014

Study shows similarities in pathogenesis of neurological diseases and HIV virus

A new study by George Washington University (GW) researcher Michael Bukrinsky, M.D., Ph.D., shows similarities in the pathogenesis of prion disease — misfolded proteins that can lead to neurological diseases — and the HIV virus.

5 Feb 2014

Researchers identify key step to prevent liver failure resulting from painkiller overdose

University of Adelaide researchers have identified a key step for the future prevention of liver failure resulting from taking too much of the everyday painkiller paracetamol (also known as acetaminophen).

5 Feb 2014

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

Patients with diabetes are at increased risk of microvascular complications, which develop when the body's small blood vessels become diseased. One of the most common problems results when wounds fail to heal properly, which can lead to ulcers, chronic infections, and in the most serious cases, limb amputations.

5 Feb 2014

Professor wins Wiley Prize for discovering how cells sense, respond to low oxygen conditions

The 13th annual Wiley Prize in Biomedical Sciences was awarded to Gregg Semenza, M.D., Ph.D., for his contribution to discovering how cells sense and respond to low oxygen conditions.

5 Feb 2014

Splicing findings offer lung cancer clues

Researchers from Spain have identified several new splicing events regulated by the oncogenic splicing factor SRSF1 in lung cancer, suggesting that their dysregulation is involved in the pathogenesis of the disease.

4 Feb 2014

Thermo Fisher Scientific acquires Life Technologies

Thermo Fisher Scientific, the world leader in serving science, today announced that it has completed its acquisition of Life Technologies Corporation (NASDAQ: LIFE) for $76.13 ($76.1311786) in cash per fully diluted common share, or approximately $13.6 billion, plus the assumption of $1.5 billion in net debt. The completion of the transaction follows the receipt of all required regulatory approvals.

4 Feb 2014

Drug used to treat schizophrenia, dementia has potential for treating liver disease

Opening up a can of worms is a good way to start hunting for new drugs, recommend researchers from Children's Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine.

4 Feb 2014

New insights into cell division could improve knowledge of cancer

New insights into how the cells in our bodies divide could improve our knowledge of a condition linked to cancer, a study suggests.

4 Feb 2014

Discovery may have implications for HIV vaccine research

NIH scientists have discovered a mechanism involved in stabilizing key HIV proteins and thereby concealing sites where some of the most powerful HIV neutralizing antibodies bind, findings with potential implications for HIV vaccine research.

4 Feb 2014

New super-resolution microscopy method could spot dozens of distinct types of biomolecules

A new microscopy method could enable scientists to generate snapshots of dozens of different biomolecules at once in a single human cell, a team from the Wyss Institute of Biologically Inspired Engineering at Harvard University reported Sunday in Nature Methods.

4 Feb 2014

Virtual Lens series of label-free live cell imaging systems announced by Phasefocus

Phase Focus Ltd (Phasefocus), the company that is revolutionising microscopy and imaging with the Phasefocus Virtual Lens®, announces the availability of the Virtual Lens series of label-free live cell imaging systems.

From Phase Focus Limited 4 Feb 2014

Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Researchers at Albert Einstein College of Medicine of Yeshiva University and Montefiore Medical Center have found a chemical "signature" in blood-forming stem cells that predicts whether patients with acute myeloid leukemia (AML) will respond to chemotherapy.

4 Feb 2014

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Researchers from Virginia Commonwealth University (VCU) Massey Cancer Center have discovered a new signaling pathway in sterile inflammation that could impact the treatment of diseases such as cancer, multiple sclerosis and rheumatoid arthritis.

4 Feb 2014

Children who received radiation as part of treatment may have lower long-term survival rates, says study

The first comprehensive, large-scale cohort study of the long-term survival of children treated for low-grade gliomas, the most common pediatric brain tumor, finds that almost 90 percent are alive 20 years later and that few die from the tumor as adults.

4 Feb 2014

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

A team of researchers has reported a novel method for tracking CD4+ T cells in people infected with HIV. CD4+ T cells are critical for immune defense against an array of pathogens and are a primary target of HIV. In the study, researchers used a unique, replication-incompetent (defective) form of HIV identified in a patient in the early 1990s.

4 Feb 2014

T Cell News and Research

Latest T Cell News and Research

Incyte enters into clinical trial collaboration agreement with Merck to evaluate safety of IDO1 inhibitor

Pfizer and Merck join forces to explore therapeutic potential of anti-PD-1 therapy

Bioengineer receives $1.4M grant to create nanoparticle system to shore up arterial walls

Scientists engineered microchip coated with blood vessel cells to study cardiovascular nanomedicine

Findings expand treatment options for hormone-dependent breast cancer

Study shows similarities in pathogenesis of neurological diseases and HIV virus

Researchers identify key step to prevent liver failure resulting from painkiller overdose

Findings explain molecular mechanisms underlying microvascular disease in diabetes patients

Professor wins Wiley Prize for discovering how cells sense, respond to low oxygen conditions

Splicing findings offer lung cancer clues

Thermo Fisher Scientific acquires Life Technologies

Drug used to treat schizophrenia, dementia has potential for treating liver disease

New insights into cell division could improve knowledge of cancer

Discovery may have implications for HIV vaccine research

New super-resolution microscopy method could spot dozens of distinct types of biomolecules

Virtual Lens series of label-free live cell imaging systems announced by Phasefocus

Chemical "signature" in blood may predict which AML patients would benefit from chemotherapy

Researchers discover new signaling pathway that could impact treatment of autoinflammatory diseases

Children who received radiation as part of treatment may have lower long-term survival rates, says study

Researchers use naturally occurring HIV variant to trace T cell lineage for 17 years

Immunology eBook

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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