T Cell News and Research

Latest T Cell News and Research

Researchers find correlation between biomarker and patient’s ability to respond to Imprime PGG

Biothera researchers have broadened their understanding of a biomarker that may enable doctors to predict which cancer patients will best respond to Imprime PGG®, the company's immunotherapy in Phase 3 drug development for colorectal cancer.

5 Dec 2013

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

The skeleton is constantly being remodelled by the breakdown of old bone by cells called osteoclasts and the formation of new bone by cells called osteoblasts. This coordinated activity is essential for maintaining healthy bone. However, excessive osteoclast activity leads to bone destruction in skeletal diseases such as osteoporosis, rheumatoid arthritis and cancer metastases in bone. A family of signaling enzymes known as phosphatidylinositol 3-kinases control diverse cell functions but, up until now, little was known about the function of specific PI3K isoforms in osteoclasts.

5 Dec 2013

Biologists discover how nerve cells recycle tiny vesicles

University of Utah and German biologists discovered how nerve cells recycle tiny bubbles or "vesicles" that send chemical nerve signals from one cell to the next. The process is much faster and different than two previously proposed mechanisms for recycling the bubbles.

5 Dec 2013

New report analyzes growth and development of stem cell field

Elsevier, EuroStemCell, and Kyoto University's Institute for Integrated Cell-Material Sciences, today released "Stem Cell Research report: Trends and Perspectives on the Evolving International Landscape" at the World Stem Cell Summit. This new, comprehensive analysis of the growth and development of the stem cell field as a whole, closely examines the research landscape for embryonic stem cell, human embryonic stem cell and induced pluripotent stem cell.

5 Dec 2013

New San Diego distracted driving education project to help curb phone while driving

Expanding their efforts to keep citizens safe on San Diego roadways, UC San Diego's Training, Research and Education for Driving Safety (TREDS) program announced today that they are launching a new distracted driving education project called Just Drive - Take Action Against Distraction, a one hour class free of charge offered to businesses in San Diego. The decision followed a recent survey by the research team, which found that 83 percent of adults who participated reported texting, talking or using a smartphone application while driving.

5 Dec 2013

IDSA released new guideline for vaccination of immunocompromised hosts

A new guideline released Thursday by the Infectious Diseases Society of America (IDSA) notes that most people with compromised immune systems are especially vulnerable to illness and should receive the flu shot and other vaccinations.

5 Dec 2013

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

Researchers at the Department of Orthopaedics, of the Second Affiliated Hospital of Xi'an Jiaotong University Health Science Center, led by Dr. Kunzheng Wang and Dr. Pei Yang have developed a novel biomimetic tissue engineered bone graft based on rabbit adipose derived stem cells (rASCs), collagen I and a porous beta-tricalcium phosphate (β-TCP) scaffold.

5 Dec 2013

B2G2 component of grape seed extract induces apoptosis in prostate cancer cells

A University of Colorado Cancer Center study published online ahead of print in the journal Nutrition and Cancer describes the laboratory synthesis of the most active component of grape seed extract, B2G2, and shows this synthesized compound induces the cell death known as apoptosis in prostate cancer cells while leaving healthy cells unharmed.

5 Dec 2013

New method for counting tumor-fighting cells to predict ovarian cancer

One way to predict survival of many types of cancer is by counting the number of tumor-attacking immune cells that have migrated into the tumor in an effort to eradicate it - a sign of the body's immune response to the cancer. However, quantifying these armies of immune cells has been difficult - until now.

5 Dec 2013

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

In an effort to lower medical costs, identify patients at risk for injury, and speed patient recovery, scientists will attempt to identify a molecular signal that indicates severity of brain-injury during a $4 million, five-year federal grant to Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix Children's Hospital and the Translational Genomics Research Institute (TGen).

5 Dec 2013

Senesco completes cohort 3 of SNS01-T Phase 1b/2a trial for multiple myeloma and lymphoma treatment

Senesco Technologies, Inc. reported today the completion of cohort 3 of its Phase 1b/2a clinical trial for its drug, SNS01-T, for the treatment of multiple myeloma and lymphoma. The Company has also received approval from its Data Review Committee to proceed to cohort 4, which is expected to require six evaluable patients.

5 Dec 2013

Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

Idera Pharmaceuticals, Inc., a clinical stage biopharmaceutical company developing a novel therapeutic approach for the treatment of autoimmune diseases and genetically defined forms of B-cell lymphoma, today announced that enrollment is open for a Phase 1/2 clinical trial of IMO-8400 in patients with Waldenström's macroglobulinemia, following acceptance of its Investigational New Drug application by the U.S. Food and Drug Administration.

5 Dec 2013

New research offers fresh insights to drug designers searching for better pain treatments

In a technical tour de force, UC San Francisco scientists have determined, at near-atomic resolution, the structure of a protein that plays a central role in the perception of pain and heat.

5 Dec 2013

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

The laboratory of Marcos Malumbres, who is head of the Spanish National Cancer Research Centre's (CNIO) Cell Division & Cancer Group, working alongside Isabel Fari-as' team from the University of Valencia, shows, in a study published today in the journal Nature Communications, how in mice the elimination of the Cdh1 protein -a sub-unit of the APC/C complex, involved in the control of cell division-prevents cellular proliferation of rapidly dividing cells.

5 Dec 2013

Baicalin inhibits colistin sulfate-induced apoptosis of PC12 cells

Baicalin, a type of flavonoid extracted from the dried root of Scutellaria baicalensis georgi, has been shown to effectively inhibit cell apoptosis. Colistin sulfate, a cyclic cationic polypeptide antibiotic, has been shown to have renal and neurological side effects.

4 Dec 2013

UCLA researchers discover how prostate cancer stem cells evolve as the disease grows

UCLA researchers have discovered how prostate cancer stem cells evolve as the disease progresses, a finding that could help point the way to more highly targeted therapies.

4 Dec 2013

BIDMC study shows carbon monoxide may have a role to play in treating cancer

In recent years, research has suggested that carbon monoxide, the highly toxic gas emitted from auto exhausts and faulty heating systems, can be used to treat certain inflammatory medical conditions. Now a study led by a research team at Beth Israel Deaconess Medical Center (BIDMC) shows for the first time that carbon monoxide may also have a role to play in treating cancer.

4 Dec 2013

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

A protein called Tet1 is partly responsible for giving primordial germ cells a clean epigenetic slate before developing into sperm and egg cells, according to a new study by researchers at Boston Children's Hospital.

4 Dec 2013

Laboratoire Cerba launches noninvasive prenatal test in multiple countries

Sequenom, Inc., a life sciences company providing innovative testing and genetic analysis solutions, announced that Laboratoire Cerba has launched its validated noninvasive prenatal test to health care providers and their patients in France, Belgium, Luxembourg and portions of the Middle East and Africa.

4 Dec 2013

Tackling orphan diseases: an interview with Damian Marron, CEO, TxCell

The exact definition of orphan diseases varies depending on where you are in the world. In the EU it's defined as a prevalence of less than 1 in 2,000, which equates to about 250,000 patients across the EU.

4 Dec 2013

T Cell News and Research

Latest T Cell News and Research

Researchers find correlation between biomarker and patient’s ability to respond to Imprime PGG

Findings suggest new approach for treating inflammatory bone diseases and skeletal metastases

Biologists discover how nerve cells recycle tiny vesicles

New report analyzes growth and development of stem cell field

New San Diego distracted driving education project to help curb phone while driving

IDSA released new guideline for vaccination of immunocompromised hosts

New study provides novel stem cell based, tissue engineered construct which can repair damaged bone

B2G2 component of grape seed extract induces apoptosis in prostate cancer cells

New method for counting tumor-fighting cells to predict ovarian cancer

Scientists receive $4M grant to identify biomarker for secondary injuries associated with brain

Senesco completes cohort 3 of SNS01-T Phase 1b/2a trial for multiple myeloma and lymphoma treatment

Enrollment opens for IMO-8400 Phase 1/2 trial in patients with Waldenström's macroglobulinemia

New research offers fresh insights to drug designers searching for better pain treatments

Blocking Cdh1 protein could accelerate development of new therapies targeting cancer

Baicalin inhibits colistin sulfate-induced apoptosis of PC12 cells

UCLA researchers discover how prostate cancer stem cells evolve as the disease grows

BIDMC study shows carbon monoxide may have a role to play in treating cancer

Tet1 helps erase epigenetic imprints from genome ahead of egg, sperm development

Laboratoire Cerba launches noninvasive prenatal test in multiple countries

Tackling orphan diseases: an interview with Damian Marron, CEO, TxCell

Immunology eBook

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Membrane proteins in focus: Turning high-risk targets into routine workflows

How metabolic phenotyping can detect viral infections in minutes

Directed enzyme evolution and the Nobel Prize: Making enzymes evolve in the lab

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