T Cell News and Research

Latest T Cell News and Research

Osteopontin plays a role in X-linked hypophosphatemia

Diagnosed in toddlers, X-linked hypophosphatemia (XLH) is the most common form of heritable rickets, in which soft bones bend and deform, and tooth abscesses develop because infections penetrate soft teeth that are not properly calcified. Researchers at McGill University and the Federal University of Sao Paulo have identified that osteopontin, a major bone and tooth substrate protein, plays a role in XLH. Their discovery may pave the way to effectively treating this rare disease.

21 Feb 2013

New bio-mimicking therapeutics could help treat skin wounds

In "before" and "after" photos from advertisements for wound-healing ointments, bandages and antibiotic creams, we see an injury transformed from an inflamed red gash to smooth and flawless skin. What we don't appreciate is the vital role that our own natural biomolecules play in the healing process, including their contribution to the growth of new cells and the development of new blood vessels that provide nutrients to those cells.

21 Feb 2013

Signaling pathway might determine genetic susceptibility for fetal alcohol spectrum disorder

Fetal alcohol syndrome is the leading preventable cause of developmental disorders in developed countries. And fetal alcohol spectrum disorder (FASD), a range of alcohol-related birth defects that includes fetal alcohol syndrome, is thought to affect as many as 1 in 100 children born in the United States.

21 Feb 2013

GCP could help lengthen life expectancy of certain prostate cancer patients

A natural, nontoxic product called genistein-combined polysaccharide, or GCP, which is commercially available in health stores, could help lengthen the life expectancy of certain prostate cancer patients, UC Davis researchers have found.

21 Feb 2013

Four genetic variations may increase risk of colorectal cancer

An international research team co-led by cancer prevention researcher Ulrike "Riki" Peters, Ph.D., M.P.H., and biostatistician Hsu Li, Ph.D., at Fred Hutchinson Cancer Research Center has identified variations in four genes that are linked to an increased risk of colorectal cancer.

21 Feb 2013

Methylene blue inactivates molecular residues that promote bonding of tau proteins

The study published in "Angewandte Chemie" might help to work out strategies for developing potential drugs. As the team of scientist including Markus Zweckstetter and Eckhard Mandelkow report, methylene blue inactivates molecular residues that promote the bonding of tau proteins.

21 Feb 2013

Immunotherapy could be answer to treating novel coronavirus

Investigation into the mechanism of action of the novelcoronavirus HCoV-EMC, which recently emerged in the Middle East, has revealed that although human bronchial epithelia are very susceptible to infection with the virus, interferon I and III were both able to significantly reduce its replication in cell culture.

20 Feb 2013

Gene mutation findings classify renal cell carcinoma

Researchers have identified mutation-defined subtypes of clear cell renal cell carcinoma that have distinct clinical outcomes.

20 Feb 2013

Consortium database model compares favorably for RCC prognosis

The International Metastatic Renal-Cell Carcinoma Database has been externally validated and is now ready for application, researchers report.

20 Feb 2013

COX-2 inhibitor extends sunitinib activity in renal cell carcinoma

The effectiveness of sunitinib for the treatment of renal cell carcinoma could be enhanced with the addition of a cyclooxygenase-2 inhibitor, study findings show.

20 Feb 2013

Metastatic tumors best for sunitinib response evaluation in mRCC

When evaluating treatment response in non-nephrectomized patients with metastatic renal cell carcinoma, the primary lesion does not have to be selected as the target lesion, researchers report.

20 Feb 2013

Possible alternative to biopsy discovered for renal cancer diagnosis

Combining positron emission tomography scanning with iodine-124 (124I)–girentuximab may offer an effective noninvasive method of diagnosing clear cell renal cell carcinoma in patients who present with a renal mass, US study results suggest.

20 Feb 2013

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

ADCs are used for a new type of targeted therapy that consists of a specific anti-cancer antibody or antibody fragment linked to a potent anti-cancer therapeutic.

20 Feb 2013

Study demonstrates function of newly discovered regulatory mechanism of myeloid cells in cancer

Researchers at the Moffitt Cancer Center have found a potential mechanism by which immune suppressive myeloid-derived suppressor cells can prevent immune response from developing in cancer.

20 Feb 2013

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Among healthy adults who were administered a cold virus, those with shorter telomere length (a structure at the end of a chromosome) in certain cells were more likely to develop experimentally-induced upper respiratory infection than participants with longer telomeres, according to results of preliminary research published in the February 20 issue of JAMA.

20 Feb 2013

Scientists demonstrate advantages of wavelength-modulated Raman spectroscopy

Raman spectroscopy has enabled incredible advances in numerous scientific fields and is a powerful tool for tissue classification and disease recognition, although there have been considerable challenges to using the method in a clinical setting. Scientists have now demonstrated the advantages of wavelength-modulated Raman spectroscopy, opening the door to wider biomedical and clinical applications such as real-time assessment of tissues during surgery.

20 Feb 2013

CINJ researcher receives PCF grant for study on lung cancer detection and prevention

Sharon Pine, PhD, a researcher at The Cancer Institute of New Jersey and assistant professor of medicine at the University of Medicine of Dentistry of New Jersey-Robert Wood Johnson Medical School has been awarded a two-year, $80,000 dollar research grant from the Prevent Cancer Foundation.

20 Feb 2013

J Cell Mol Med, Microbial Biotechnology join Wiley Open Access publishing program

John Wiley & Sons, Inc., announced today that Journal of Cellular and Molecular Medicine and Microbial Biotechnology have joined the Wiley Open Access publishing program. All articles in these two journals are now open access and free to view, download and share.

20 Feb 2013

Ipsen, Inspiration Biopharmaceuticals sell IB1001 hemophilia B product to Cangene

Inspiration Biopharmaceuticals and Ipsen today announced the closing of the sale of the proprietary hemophilia B product, IB1001 (recombinant FIX), to Cangene Corporation.

20 Feb 2013

Immature malaria parasites more resistant to treatment with artemisinin

New research has revealed that immature malaria parasites are more resistant to treatment with key antimalarial drugs than older parasites, a finding that could lead to more effective treatments for a disease that kills one person every minute and is developing resistance to drugs at an alarming rate.

20 Feb 2013

T Cell News and Research

Latest T Cell News and Research

Osteopontin plays a role in X-linked hypophosphatemia

New bio-mimicking therapeutics could help treat skin wounds

Signaling pathway might determine genetic susceptibility for fetal alcohol spectrum disorder

GCP could help lengthen life expectancy of certain prostate cancer patients

Four genetic variations may increase risk of colorectal cancer

Methylene blue inactivates molecular residues that promote bonding of tau proteins

Immunotherapy could be answer to treating novel coronavirus

Gene mutation findings classify renal cell carcinoma

Consortium database model compares favorably for RCC prognosis

COX-2 inhibitor extends sunitinib activity in renal cell carcinoma

Metastatic tumors best for sunitinib response evaluation in mRCC

Possible alternative to biopsy discovered for renal cancer diagnosis

Antibody-drug conjugates (ADCs): an interview with Dr Marco Timmers, CSO at Synthon Biopharmaceuticals

Study demonstrates function of newly discovered regulatory mechanism of myeloid cells in cancer

Healthy adults with shorter telomere length more likely to develop upper respiratory infection

Scientists demonstrate advantages of wavelength-modulated Raman spectroscopy

CINJ researcher receives PCF grant for study on lung cancer detection and prevention

J Cell Mol Med, Microbial Biotechnology join Wiley Open Access publishing program

Ipsen, Inspiration Biopharmaceuticals sell IB1001 hemophilia B product to Cangene

Immature malaria parasites more resistant to treatment with artemisinin

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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