T Cell News and Research

Latest T Cell News and Research

MOZ protein could explain variations in severity of DiGeorge syndrome

The discovery of a 'switch' that modifies a gene known to be essential for normal heart development could explain variations in the severity of birth defects in children with DiGeorge syndrome.

24 Aug 2012

Salivary IL-6 could predict recurrence after surgery in mouth cancer patients

Salivary levels of the proinflammatory cytokine interleukin-6 could be a useful predictor for locoregional recurrence in oral squamous cell carcinoma patients who are treated surgically, report researchers.

23 Aug 2012

Researcher describes structure and function of tuberculosis efflux pump regulator

Edward Yu took note of the facts - nearly 2 million deaths each year, 9 million infected each year, developments of multidrug-resistant, extensively drug-resistant and now totally drug-resistant strains - and decided to shift his research focus to tuberculosis.

23 Aug 2012

Microtubule stiffening worsens skeletal muscle degeneration in Duchenne muscular dystrophy

University of Maryland (UM) researchers and collaborators report in the journal Science Signaling that skeletal muscle degeneration in Duchenne muscular dystrophy (DMD) is worsened by stiffening of the microtubule cytoskeleton that provides structure inside muscle cells.

23 Aug 2012

Diabetes risk may be higher in childhood cancer survivors who received radiotherapy

Childhood cancer survivors who underwent radiotherapy treatment that exposed their pancreas to radiation may be at higher risk of developing diabetes in later life, according to an Article published Online First in The Lancet Oncology.

23 Aug 2012

University of Tübingen microbiologist wins 2012 Sofja Kovalevskaja Award

Samuel Wagner examines how bacteria start infections - aiming to stop the mechanism and maybe use it in treatment. The Alexander von Humboldt Foundation has announced that one of this year's Sofja Kovalevskaja Awards goes this year to microbiologist Prof. Dr. Samuel Wagner, a junior professor at the University of Tübingen.

23 Aug 2012

Proteonomix enters license agreement for new anti-tumor technology

Proteonomix, Inc., a biotechnology company focused on developing therapeutics based upon the use of human cells and their derivatives, today announced that it has entered into an exclusive worldwide license agreement for a novel source of primary human cells that secrete a factor capable of inhibiting tumor cell growth and causing tumor cell death.

23 Aug 2012

New imaging technique reveals the brain's continuous renovation

Using bioluminescent proteins from a jellyfish, a team of scientists has lit up the inside of a neuron, capturing spectacular video footage that shows the movement of proteins throughout the cell.

23 Aug 2012

New results describe development of DC cancer vaccine with enhanced immunogenic potential

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, and collaborators at Radboud University Nijmegen Medical Centre in the Netherlands announced today that they have published new pre-clinical results in the journal Cancer Immunology Immunotherapy describing the development of a dendritic cell (DC) cancer vaccine with enhanced immunogenic potential.

23 Aug 2012

Study might help solve the biggest mystery of Parkinson’s

The recent discoveries that α-Synuclein(α-Syn) protein, a central player in Parkinson´s disease (PD) brain destruction, could not only pass from one neuron to another but also exist outside neuronal cells has led to major rethink on the disease.

23 Aug 2012

Newly discovered on/off switch in enzymes may help battle fat-related disease

Enzymes involved in breaking down fat can now be manipulated to work three times harder by turning on a molecular switch recently observed by chemists at the University of Copenhagen. Being able to control this chemical on/off button could have massive implications for curing diseases related to obesity including diabetes, cardio vascular disease, stroke and even skin problems like acne. But the implications may be wider.

23 Aug 2012

Study identifies how RNA viruses hijack a host cell to multiply

By discovering how certain viruses use their host cells to replicate, UC Irvine microbiologists have identified a new approach to the development of universal treatments for viral illnesses such as meningitis, encephalitis, hepatitis and possibly the common cold.

23 Aug 2012

TREM-1 gene disrupts inflammatory process implicated in liver cancer

Researchers at the Georgia Health Sciences University Cancer Center have identified a gene that disrupts the inflammatory process implicated in liver cancer.

23 Aug 2012

EMD Millipore enters definitive agreement to acquire Biochrom

EMD Millipore, the Life Science division of Merck KGaA of Darmstadt, Germany, today announced that it has entered into definitive agreements to acquire Biochrom AG located in Berlin, Germany.

From Biochrom Ltd. 23 Aug 2012

Alcohol can cause more than one pattern of birth defects

A collaborative research effort by scientists at the University of North Carolina School of Medicine, Duke University, and University College of London in the UK, sheds new light on alcohol-related birth defects.

23 Aug 2012

Spicy solution for viral infection

Curcumin, the main compound in the spice turmeric, prevents replication of mosquito-borne Rift Valley Fever virus in infected cells, report researchers.

22 Aug 2012

Blood cells returned to stem cell state by Johns Hopkins researchers

Johns Hopkins scientists have developed a reliable method to turn the clock back on blood cells, restoring them to a primitive stem cell state from which they can then develop into any other type of cell in the body.

22 Aug 2012

RNA switches can better equip and regulate viruses for many therapeutic applications

Numerous viruses are used in the service of science today. They serve as gene taxis to transfer therapeutic genes into body cells or as therapeutic viruses targeted to infect and destroy cancer cells. For such applications, the viruses are often equipped with additional genes, such as for immune mediators or for proteins inducing programmed cell death. However, these gene products can harm the body if they are released at the wrong moment or at excessive levels.

22 Aug 2012

Abortion issue gets spotlight in swing states

Meanwhile, as the GOP prepares to include tough anti-abortion positions in its party platform, the Associated Press notes that voters in the presidential race will get a stark choice on social issues, including access to birth control and abortion rights.

22 Aug 2012

Acai supplementation could protect against oxidative stress and triple flies' lifespans

Bewildered by the array of antioxidant fruit juices on display in the supermarket and the promises they make? To sort out the antioxidant properties of fruits and berries, scientists at Emory University School of Medicine turned to fruit flies for help.

22 Aug 2012