T Cell News and Research

Latest T Cell News and Research

Cleavage stage embryo with aneuploidy can undergo genetic normalisation process

Professor William G. Kearns told the annual meeting of the European Society of Human Reproduction and Embryology that a three-day-old embryo with an incorrect number of chromosomes was capable of undergoing "a dynamic process of genetic normalisation" so that by day five, when it had developed to the blastocyst stage, it had become euploid, with the correct number of chromosomes.

5 Jul 2011

PET imaging technique may identify TKI-responsive lung cancer

A non-invasive PET imaging technique may identify lung cancers that respond best to tyrosine kinase inhibitors (TKIs), allowing doctors to better select patients for personalized therapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

LCMC finds 9.6% of lung cancer patients with ALK rearrangement

ALK rearrangement has been found in 9.6% of lung cancer patients tested in the Lung Cancer Mutation Consortium, and MET amplification in another 4.1%, reflecting how many patients might benefit from targeted therapies such as crizotinib, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

Erlotinib phase III study results on lung cancer presented at IASLC conference

In the first phase III study to include Western lung cancer patients, first-line treatment with erlotinib (Tarceva) nearly doubled progression-free survival compared with chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer.

5 Jul 2011

Study helps explain why fatty foods are complicit in weight gain

Recent studies have revealed potato chips and french fries to be the worst contributors to weight gain - and with good reason. Have you ever wondered why you can't eat just one chip or a single fry? It's not just the carbohydrates at fault.

5 Jul 2011

Fruit flies with poor posture help scientists understand human intellectual disability

Clumsy fruit flies with poor posture are helping an international team of scientists understand inherited intellectual disability in humans - and vice versa.

5 Jul 2011

Research addresses chromosomal imbalance in embryos

Joint research between the University of Kent's Professor Darren Griffin, London Bridge Fertility Centre and BlueGnome Ltd has addressed chromosomal imbalance in embryos, a condition that is currently the major cause of pregnancy loss in IVF.

4 Jul 2011

Ways to protect children from X-ray radiation

The risk to children's health from X-ray radiation is easy to reduce without compromising diagnostic accuracy. Gerhard Alzen and Gabriele Benz-Bohm describe some ways to achieve this in the current edition of Deutsches Ärzteblatt International.

4 Jul 2011

LuCED test can improve utility of low-dose CT screening for early lung cancer detection

VisionGate, Inc., a company developing a revolutionary non-invasive test for the early detection of lung cancer, today announced that it will present data showing how adjunctive use of its LuCED- test can improve the utility of low dose x-ray computed tomography (CT) screening for the early detection of lung cancer in high risk individuals.

4 Jul 2011

New insight into oocyte chromosome abnormalities

Ovarian stimulation undertaken by women of advanced maternal age receiving fertility treatment may be disrupting the normal pattern of meiosis - a critical process of chromosome duplication followed by two specialised cell divisions in the production of oocytes and sperm - and leading to abnormalities of chromosome copy numbers that result in IVF failure, pregnancy loss or, more rarely, the birth of affected children with conditions such as Down's syndrome, which is caused by the inheritance of three copies of chromosome 21.

4 Jul 2011

Scientists use statistical approach to assess order of genetic abnormalities in cancers

Zeroing in on the early cell mutations that enable a cancer to grow is one of the best ways to find a personalized therapy to stop it. Scientists were able to use a statistical approach for the first time to map out the order in which these abnormalities form to analyze the pattern of DNA changes in advanced skin and ovarian tumors.

2 Jul 2011

Johns Hopkins team reconstitutes single stem cells' family tree

A Johns Hopkins team has discovered in young adult mice that a lone brain stem cell is capable not only of replacing itself and giving rise to specialized neurons and glia - important types of brain cells - but also of taking a wholly unexpected path: generating two new brain stem cells.

2 Jul 2011

New stem cell bioprinting for uniform, controlled size embryoid body formation

Ever since an ordinary office inkjet printer had its ink cartridges swapped out for a cargo of cells about 10 years ago and sprayed out cell-packed droplets to create living tissue, scientists and engineers have never looked at office equipment in quite the same way. They dream of using a specialized bio-inkjet printer to grow new body parts for organ transplants or tissues for making regenerative medicine repairs to ailing bodies.

2 Jul 2011

U-M researchers a step closer to developing treatments for aging and chronic diseases

As our bodies first form, developing cells are a lot like children put on the school bus with their names and addresses pinned to their shirts. The notes identify one as a future heart cell, another as a liver cell, a third as a neuron. And that's what they each grow up to be. But once those cells reach adulthood, changes to those original marching orders caused by aging, disease and other stressors like smoking can precipitate a kind of identity crisis, researchers at the University of Michigan Health System have found.

2 Jul 2011

European joint project to develop novel HCV vaccine based on nanotechnology

HCVAX is a European joint project that reaches out to develop a vaccine against hepatitis C based on nanotechnology. The German Helmholtz Centre for Infection Research in Braunschweig and its department "Vaccinology and Applied Microbiology" is now a part of the transnational consortium with researchers from Germany, France and Switzerland.

2 Jul 2011

Transnational research group examines how viruses evade immune system

Understanding the tricks and survival strategies of viruses to effectively combat them: That is the goal of the virtual institute VISTRIE that received its funding commitment today.

2 Jul 2011

STSI receives NIH grant to conduct heart-based research

Researchers looking to find a root cause for heart attacks and coronary artery disease will soon begin using a novel investigative approach that borders on science fiction as they work toward the holy grail of American medicine: preventing the nation's No. 1 killer.

2 Jul 2011

Intravenous nutrition does not have a positive effect if administered early

Critically ill patients receive intravenous nutrition - via an infusion in a large vein - when nutrition via a stomach or intestinal tube is insufficient. There is international dispute over the correct timing of intravenous nutrition: European guidelines recommend administering intravenous nutrition within 48 hours to prevent malnutrition.

1 Jul 2011

GWAS identifies 15 gene variants responsible for diversity of white blood cell counts

A trio of large-scale genome-wide association studies, or GWAS, have identified more than 15 gene variants responsible for the diversity of white blood cell counts among whites, African-Americans, and Japanese.

1 Jul 2011

ASCB Childcare grant eases science career vs. family conflict

For many young scientists, particularly women, research careers hang precariously between scientific and family responsibilities. That's a balance that the American Society for Cell Biology (ASCB) hopes to tip towards the plus side with a $60,000 grant from Nature Publishing Group (NPG) to underwrite childcare expenses at the ASCB's career-critical Annual Meetings over the next five years.

1 Jul 2011