T Cell News and Research

Latest T Cell News and Research

Initial data from resminostat Phase II Hodgkin Lymphoma trial to be presented at 52nd ASH

4SC, a drug discovery and development company focused on autoimmune and cancer indications, today announced that initial safety and efficacy data from its ongoing Phase II Study with resminostat, a pan-Histone Deacetylase (HDAC) Inhibitor, in relapsed/refractory Hodgkin Lymphoma (HL) patients after high dose chemotherapy and autologous hematopoietic stem cell transplantation will be presented at the 52nd Annual Meeting of the American Society of Hematology (ASH) in Orlando, Florida, USA.

1 Dec 2010

Mitochondrial brain changes contribute to risk of Alzheimer's disease: Research

What are the earliest brain changes associated with the risk of developing Alzheimer's disease. A scientific report published in the October Journal of Alzheimer's Disease finds reduced activity of an energy-generating enzyme in deceased young adult brain donors who carry a common genetic risk factor for Alzheimer's disease.

1 Dec 2010

Physician-scientists enroll patients with NSCLC cancer in MAGE-A3 Phase III trial

An experimental immunotherapy may someday become the newest weapon against lung cancer. Physician-scientists from Weill Cornell Medical College and Columbia University Medical Center are enrolling patients with non-small cell lung cancer (NSCLC) at NewYork-Presbyterian Hospital as part of an ongoing Phase III trial.

1 Dec 2010

Odors in womb sensitize fetus to smells, alters brain development

A major new study shows that a pregnant mother's diet not only sensitizes the fetus to those smells and flavors, but physically changes the brain directly impacting what the infant eats and drinks in the future.

1 Dec 2010

Results of pixantrone phase III trial for non-Hodgkin's lymphoma to be presented at Hematology Meeting

Cell Therapeutics, Inc. announced today that Ruth Pettengell, M.D. of St. George's Hospital, University of London, the lead investigator for the PIX 301 EXTEND trial will present end of study results for the pixantrone phase III trial in relapsed/refractory aggressive non-Hodgkin's lymphoma at the 52nd Annual Meeting of the American Society of Hematology on Sunday, December 5, 2010 in Orlando, Florida.

1 Dec 2010

Not all HIV viruses are bad for the immune system

Mayo Clinic researchers have shown why, in a minority of HIV patients, immune function improves despite a lack of response to standard anti-retroviral treatment. In these cases, researchers say, the virus has lost its ability to kill immune cells. The findings appear in the online journal PLoS Pathogens.

1 Dec 2010

Black rice may help soothe inflammation: Research

The latest episode in the American Chemical Society's (ACS) award-winning podcast series, "Global Challenges/Chemistry Solutions," focuses on the discovery that black rice a little-known variety of the grain that is the staple food for one-third of the world's population may help soothe the inflammation involved in allergies, asthma and other diseases.

1 Dec 2010

Precision Therapeutics to present abstracts on breast cancer therapy at San Antonio Symposium

Precision Therapeutics will present two abstracts at the 33rd Annual San Antonio Breast Cancer Symposium, which will be held December 8-12, 2010 in San Antonio, Texas.

1 Dec 2010

Research could lead to new drug treatment for metabolic diseases

A team of Harvard School of Public Health (HSPH) scientists report finding a molecular "switch" that can "turn off" some cellular processes that are protective against aging and metabolic diseases. While more research is needed, the findings may open doors for new drug treatments to halt or slow development of metabolic diseases like type 2 diabetes or heart disease. The research findings appear in the December 1, 2010 issue of Cell Metabolism.

1 Dec 2010

Angptl4 protein deficiency could promote inflammatory response in people who consume high saturated fat

A new report in the December Cell Metabolism identifies a protein without which diets high in saturated fat lead to a massive inflammatory response that can prove fatal. The studies in mice suggest that deficiencies in this protective pathway could promote inflammation in those who regularly consume high levels of saturated fat.

1 Dec 2010

MRS imaging technique may help diagnose chronic traumatic encephalopathy

In a study of ex-pro athletes, researchers found that a specialized imaging technique called magnetic resonance spectroscopy (MRS) may help diagnose chronic traumatic encephalopathy (CTE), a disorder caused by repetitive head trauma that currently can only be definitively diagnosed at autopsy. Results of the study were presented today at the annual meeting of the Radiological Society of North America (RSNA).

1 Dec 2010

Mitochondrial dysfunction observed in children with full syndrome autism

Preliminary research has found that children with autism are more likely to have impaired mitochondrial function (structures within cells responsible for energy production) and mitochondrial DNA abnormalities than typically developing children, according to a study in the December 1 issue of JAMA.

1 Dec 2010

PhRMA reports 100 new medicines and vaccines in development for HIV/AIDS

America's biopharmaceutical research companies are working on 100 new medicines and vaccines [video] to treat and prevent HIV/AIDS and related conditions, according to a new report from the Pharmaceutical Research and Manufacturers of America (PhRMA).

1 Dec 2010

Rush University enrolls first U.S. patient in international clinical trial for melanoma

Rush University Medical Center has just enrolled the first U.S. patient in an international clinical trial testing a novel drug to treat certain kinds of melanoma, a deadly skin cancer that in its advanced stages currently has few effective treatments.

1 Dec 2010

Research on patients' immune system may lead to new diagnostic tool for HIV treatment

1 Dec 2010

Scientists create couch potato mouse model to study muscle function

Daniel Kelly, M.D., and his colleagues at Sanford-Burnham Medical Research Institute (Sanford-Burnham) at Lake Nona have unveiled a surprising new model for studying muscle function: the couch potato mouse.

1 Dec 2010

Pfizer awards $2.1 million grant to NCCN to evaluate axitinib in solid tumors

The National Comprehensive Cancer Network has been awarded a $2.1 million grant from Pfizer to develop a program to scientifically evaluate and define the clinical activity of axitinib in various tumor types.

1 Dec 2010

Elorac's naloxone lotion receives FDA Orphan Drug Designation for pruritus associated with mycosis fungoides

Elorac, Inc., a rapidly growing specialty pharmaceutical company focused on the treatment of dermatological disorders announced that it has been granted Orphan Drug Designation by the U.S. Food and Drug Administration for its naloxone lotion for the topical treatment of pruritus accompanying cutaneous t-cell lymphoma (CTCL, also known as mycosis fungoides).

1 Dec 2010

ACT files IND application to initiate Phase I/II study for Dry AMD

Advanced Cell Technology, Inc. announced today that it has filed an Investigational New Drug (IND) Application with the US Food and Drug Administration (FDA) to initiate a Phase I/II multicenter study using human embryonic stem cell (hESC) derived retinal pigment epithelial (RPE) cells to treat patients with Dry Age-Related Macular Degeneration (Dry AMD).

30 Nov 2010

NIA awards Aphios Phase I Fast Track SBIR grant for development of novel AD nanodrug

Aphios® Corporation today announced that it was awarded Phase I of a Fast Track SBIR grant from the National Institute of Aging (NIA), National Institutes of Health (NIH) for Developing a Novel Alzheimer's Disease Nanodrug.

30 Nov 2010

T Cell News and Research

Latest T Cell News and Research

Initial data from resminostat Phase II Hodgkin Lymphoma trial to be presented at 52nd ASH

Mitochondrial brain changes contribute to risk of Alzheimer's disease: Research

Physician-scientists enroll patients with NSCLC cancer in MAGE-A3 Phase III trial

Odors in womb sensitize fetus to smells, alters brain development

Results of pixantrone phase III trial for non-Hodgkin's lymphoma to be presented at Hematology Meeting

Not all HIV viruses are bad for the immune system

Black rice may help soothe inflammation: Research

Precision Therapeutics to present abstracts on breast cancer therapy at San Antonio Symposium

Research could lead to new drug treatment for metabolic diseases

Angptl4 protein deficiency could promote inflammatory response in people who consume high saturated fat

MRS imaging technique may help diagnose chronic traumatic encephalopathy

Mitochondrial dysfunction observed in children with full syndrome autism

PhRMA reports 100 new medicines and vaccines in development for HIV/AIDS

Rush University enrolls first U.S. patient in international clinical trial for melanoma

Research on patients' immune system may lead to new diagnostic tool for HIV treatment

Scientists create couch potato mouse model to study muscle function

Pfizer awards $2.1 million grant to NCCN to evaluate axitinib in solid tumors

Elorac's naloxone lotion receives FDA Orphan Drug Designation for pruritus associated with mycosis fungoides

ACT files IND application to initiate Phase I/II study for Dry AMD

NIA awards Aphios Phase I Fast Track SBIR grant for development of novel AD nanodrug

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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