T Cell News and Research

Latest T Cell News and Research

Exelixis enters two new collaboration agreements with Bristol-Myers Squibb

Exelixis, Inc. announced today that it has entered into two new collaboration agreements with Bristol-Myers Squibb Company. Under the first agreement, Exelixis will grant to Bristol-Myers Squibb an exclusive license to its small-molecule TGR5 agonist program including backups.

11 Oct 2010

'Achilles heel' for HCV infection

Scientists at the Gladstone Institute of Virology and Immunology (GIVI) have found that an enzyme associated with the storage of fat in the liver is required for the infectious activity of the hepatitis C virus (HCV). This discovery may offer a new strategy for treating the infection.

11 Oct 2010

Shift work can cause cancer: Research

Shift work can cause cancer. In the new issue of the Deutsches Ärzteblatt International, Thomas C. Erren and colleagues describe the current state of knowledge in this area and point out the challenges lying ahead.

11 Oct 2010

Takeda, Envoy enter three-year research alliance to develop schizophrenia drug

Takeda Pharmaceutical Company Limited, a global pharmaceutical company, and Envoy Therapeutics Inc., a recently formed drug discovery company, today announced that they have formed a three-year research alliance aimed at discovering drugs for schizophrenia that will have greater efficacy and safety compared to current therapies.

11 Oct 2010

Phase-II clinical trial of MLN8237 drug shows promising results for treating ovarian cancer

A drug being developed as a treatment for ovarian cancer has shown single agent activity with durable disease control in some patients in a Phase-II clinical trial, an international research group has reported.

11 Oct 2010

Researchers find new surface adaptation mechanism of biofilm-forming pathogen

Many drug-resistant infections are the result of bacterial biofilms, structured aggregates of bacteria that live on surfaces and that are extremely resistant to environmental stresses. These biofilms impact human health in many ways - cystic fibrosis, for example, is a disease in which patients die from airway bacterial biofilm infections that are invulnerable to even the most potent antibiotics.

11 Oct 2010

Scientists identify molecular mechanism of muscle stem cell differentiation

Under normal circumstances, adult stem cells reside in muscle tissue, where they can differentiate into a number of different cell types. After an injury (or even a tough workout), muscles are inflamed as cells and molecules flood the area to control damage and begin repairs. When called upon to replace muscle tissue damaged by injury or genetic disease, some muscle stem cells differentiate, becoming new muscle cells, while others make more stem cells. At Sanford-Burnham Medical Research Institute (Sanford-Burnham), a team of scientists led by Pier Lorenzo Puri, M.D., Ph.D., recently uncovered the molecular messengers that translate inflammatory signals into the genetic changes that tell muscle stem cells to differentiate.

11 Oct 2010

Infinity announces preliminary results of IPI-926 Phase 1 study in patients with solid tumors

Infinity Pharmaceuticals, Inc. today announced promising preliminary results from a Phase 1 study of IPI-926, its novel, oral small molecule that targets the Hedgehog pathway.

11 Oct 2010

Cell Cure to receive equity investment of $7.1 million to develop stem cell-based therapies

BioTime, Inc. Cell Cure Neurosciences Ltd., and Hadasit Bio-Holdings Ltd. jointly announced today that Cell Cure will receive an equity investment of $7.1 million from BioTime, Teva Pharmaceutical Industries Ltd., and Hadasit Bio-Holdings (HBL).

11 Oct 2010

Cell Cure, Teva Pharmaceutical enter license option agreement for OpRegen product

BioTime, Inc., Cell Cure Neurosciences Ltd., and Hadasit Bio-Holdings Ltd. jointly announced today that Cell Cure and Teva Pharmaceutical Industries Ltd. have entered into an exclusive license option agreement to develop and commercialize Cell Cure's OpRegen product for the treatment of age-related macular degeneration (AMD).

11 Oct 2010

Defense Department's AFIRM to fund Stratatech's Phase IIb clinical trial of StrataGraft tissue

Stratatech Corp., a regenerative medicine company focused on the commercialization of cell-based, tissue-engineered skin substitute products, today announced that the Defense Department's Armed Forces Institute of Regenerative Medicine will fund the Phase IIb clinical trial of the company's flagship StrataGraft living human skin substitute tissue.

8 Oct 2010

Mouse study may help develop new therapies for spinal cord injury

Researchers at Karolinska Institutet have shown how stem cells, together with other cells, repair damaged tissue in the mouse spinal cord. The results are of potential significance to the development of therapies for spinal cord injury.

8 Oct 2010

Biologists determine three-dimensional structure of molecule involved in HIV, cancer

In a technical tour de force, structural biologists funded by the National Institutes of Health have determined the three-dimensional structure of a molecule involved in HIV infection and in many forms of cancer. The high-resolution structure sheds light on how the molecule functions and could point to ways to control its activity, potentially locking out HIV and stalling cancer's spread.

8 Oct 2010

Cincinnati Children's Hospital Medical Center named Centers of Excellence for Molecular Hematology

Cincinnati Children's Hospital Medical Center has been named one of five national Centers of Excellence for Molecular Hematology to find new gene and cell therapies for inherited diseases affecting blood cells.

8 Oct 2010

Roche´s Cellavista System useful for automated mES colony imaging: Study

A recent study depicted the use of Roche´s Cellavista System to rapidly and effectively carry out a clonal analysis of embryonic stem colony self-renewal in an end-point assay. The Cellavista System proved to be useful for automated mES colony imaging, as well as characterization of colonies as differentiated and undifferentiated based on gating of morphological and intensity criteria. Little or no interference from the feeder cell layers was seen in the analysis of the images.

8 Oct 2010

T Cell News and Research

Latest T Cell News and Research

Exelixis enters two new collaboration agreements with Bristol-Myers Squibb

'Achilles heel' for HCV infection

Shift work can cause cancer: Research

Takeda, Envoy enter three-year research alliance to develop schizophrenia drug

Phase-II clinical trial of MLN8237 drug shows promising results for treating ovarian cancer

Researchers find new surface adaptation mechanism of biofilm-forming pathogen

Scientists identify molecular mechanism of muscle stem cell differentiation

Infinity announces preliminary results of IPI-926 Phase 1 study in patients with solid tumors

Cell Cure to receive equity investment of $7.1 million to develop stem cell-based therapies

Cell Cure, Teva Pharmaceutical enter license option agreement for OpRegen product

Defense Department's AFIRM to fund Stratatech's Phase IIb clinical trial of StrataGraft tissue

Mouse study may help develop new therapies for spinal cord injury

Biologists determine three-dimensional structure of molecule involved in HIV, cancer

Cincinnati Children's Hospital Medical Center named Centers of Excellence for Molecular Hematology

Roche´s Cellavista System useful for automated mES colony imaging: Study

Scientists engineer bacterial cell wall with small molecules to combat diseases

StemCells provides update on PMD Phase I clinical trial

Two-day symposium marks an extraordinary decade for Brown Institute for Brain Science

Researchers identify molecular mechanism that regulate metastasis of melanoma cells

Intestinal bacteria send signals that promote cell proliferation in Wnt signaling pathway

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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