T Cell News and Research

Latest T Cell News and Research

Brentuximab vedotin-chemotherapy combination clinical trial for Hodgkin lymphoma announced

Seattle Genetics, Inc. and Millennium Pharmaceuticals, Inc.: The Takeda Oncology Company today announced that they have initiated a phase I clinical trial of brentuximab vedotin (SGN-35) in combination with chemotherapy for the treatment of newly diagnosed Hodgkin lymphoma patients. Brentuximab vedotin is an antibody-drug conjugate (ADC) that is also in single-agent clinical trials, including a pivotal trial for relapsed and refractory Hodgkin lymphoma and a phase II trial for systemic anaplastic large cell lymphoma.

4 Feb 2010

Prolactin reduces the levels of BCL6 protein and prevents aggressive breast cancer

Researchers from the Kimmel Cancer Center at Jefferson have found a mechanism by which a hormone responsible for milk production blocks an oncogene that makes breast cancer more aggressive.

4 Feb 2010

BRAF drugs may accelerate tumour growth in cancer patients with faulty RAS gene

A team of UK scientists has made the unexpected discovery that drugs which target a well known fault in a protein called BRAF could actually fuel the progression of cancer in some cases. The findings of this study, which was jointly funded by Cancer Research UK, The Institute of Cancer Research (ICR) and the Wellcome Trust are published in Cell.

3 Feb 2010

Innovative discharge program reduces congestive heart failure readmissions

An innovative discharge program developed by Saddleback Memorial Medical Center combining coordination of hospital and community resources, strong patient education and the IDEAL LIFE Bluetooth-enabled wireless remote health monitoring system has helped to reduce congestive heart failure (CHF) readmissions by 50 percent

3 Feb 2010

Penn Medicine experts available to offer medical insight and commentary during 2010 Winter Olympics

Experts from the University of Pennsylvania School of Medicine are available to offer expert medical insight and commentary during the 2010 Winter Olympics in Vancouver on issues ranging from the effects of performance enhancing drugs to concerns about the spread of novel H1N1, head trauma and more.

3 Feb 2010

New 3D scaffold for stem cell renewal

Medical researchers were shocked to discover that virtually all human embryonic stem cell lines being used in 2005 were contaminated. Animal byproducts used to line Petri dishes had left traces on the human cells. If those cells had been implanted in a human body they likely would have been rejected by the patient's immune system.

3 Feb 2010

Research opens new avenues for understanding genetic basis of type 2 diabetes

Together with colleagues in Barcelona, researchers at the University of North Carolina at Chapel Hill have generated a complete map of the areas of the genome that control which genes are "turned on" or "off."

3 Feb 2010

TGen, Horizon Discovery partner in development of novel cancer cell-lines

The Translational Genomics Research Institute (TGen) and Horizon Discovery today announced plans to develop human disease models for use in TGen's cancer research.

3 Feb 2010

New bioanalytical methods have potential for investigative and screening applications

The Springer journal Analytical and Bioanalytical Chemistry (ABC) has chosen Jean-Philippe Frimat (29) as the recipient of its Best Paper Award 2009. Frimat is the lead author of a paper in ABC on plasma stencilling methods for cell patterning.

3 Feb 2010

Baker's yeast promising against cancer

A researcher at Charles Drew University of Medicine and Science is investigating the potential use of non-pathogenic baker's yeast as a promising, natural therapy for cancer.

3 Feb 2010

GE Healthcare expands ecomagination product portfolio, adds Centricity Enterprise EMR solution

GE Healthcare, a unit of General Electric Company, today announced that it has expanded its portfolio of ecomagination products aimed at helping healthcare companies and hospitals reduce cost and waste while positively impacting the environment. The GE ecomagination portfolio of more than 85 products now includes two new healthcare products and three product categories, including the Centricity Enterprise Electronic Medical Record (EMR) solution.

3 Feb 2010

UCR purchases Nikon BioStation CT technology to assist in stem cell research

Stem cell research at the University of California, Riverside is about to gather speed thanks to the establishment of a new Stem Cell Core Facility (SCCF) - a shared facility providing infrastructure, equipment, and trained personnel for doing stem cell research that ordinarily would not be available in most laboratories.

3 Feb 2010

MV vaccine prevents TB in people with HIV infection

Results from clinical trials conducted in Tanzania show that a new vaccine against tuberculosis, Mycobacterium vaccae (MV), is effective in preventing tuberculosis in people with HIV infection. Findings from the trials, which were conducted by investigators from Dartmouth Medical School in the United States, will be published in the next issue of AIDS, the leading journal in the field of HIV and AIDS research. The journal is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health, a leading provider of information and business intelligence for students, professionals, and institutions in medicine, nursing, allied health, and pharmacy.

3 Feb 2010

Researchers find three different degenerative brain disorders linked by toxic form of Elk-1 protein

For the first time, researchers from the University of Pennsylvania School of Medicine have found that three different degenerative brain disorders are linked by a toxic form of the same protein. The protein, called Elk-1, was found in clumps of misshaped proteins that are the hallmarks of Parkinson's disease, Alzheimer's disease, and Huntington's disease.

3 Feb 2010

Scientists are getting closer to prove how cholesterol causes heart disease

By considering molecular-level events on a broader scale, researchers now have a clearer, if more complicated, picture of how one class of immune cells goes wrong when loaded with cholesterol. The findings reported in the February 3rd issue of Cell Metabolism, a Cell Press publication, show that, when it comes to the development of atherosclerosis and heart disease, it's not about any one bad actor-it's about a network gone awry.

3 Feb 2010

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Repros Therapeutics Inc. today announced that the Company has received verbal confirmation from the Division of Metabolic and Endocrine Drug Products of the Food and Drug Agency that the Company may initiate its Investigational New Drug Application for the study of oral Androxal® in the treatment of hypogonadal men with Type II Diabetes (T2D) with a Phase IIa trial.

3 Feb 2010

Research shows DNA looping can impact gene expression

University of Michigan researchers have shown that tension on DNA molecules can affect gene expression---the process at the heart of biological function that tells a cell what to do.

3 Feb 2010

Study could provide potential therapeutic strategies for treating prostate cancer

Prostate cancer cells are more likely to spread to other parts of the body if a specific gene quits functioning normally, according to new data from researchers at UT Southwestern Medical Center.

3 Feb 2010

Fluxion Biosciences to defend against alleged automated patch clamp system patent infringement lawsuit

Fluxion Biosciences, Inc. announced today that a lawsuit alleging patent infringement had been filed against it in the US District Court of Northern California by Cellectricon AB, its competitor in the field of automated ion channel screening systems for drug discovery. Cellectricon has asserted U.S. Patents Nos. 7,390,650, 7,470,518, and 7,563,614 in the litigation, as well as U.S. Patent No. 5,376,252, which is owned by Gyros and licensed to Cellectricon.

From Fluxion Biosciences 3 Feb 2010

Research suggests growth factor gene plays a central role in palate development

Cleft palate has been linked to dozens of genes. During their investigation of one of these genes, researchers at Washington University School of Medicine in St. Louis were surprised to find that cleft palate occurs both when the gene is more active and when it is less active than normal.

3 Feb 2010

T Cell News and Research

Latest T Cell News and Research

Brentuximab vedotin-chemotherapy combination clinical trial for Hodgkin lymphoma announced

Prolactin reduces the levels of BCL6 protein and prevents aggressive breast cancer

BRAF drugs may accelerate tumour growth in cancer patients with faulty RAS gene

Innovative discharge program reduces congestive heart failure readmissions

Penn Medicine experts available to offer medical insight and commentary during 2010 Winter Olympics

New 3D scaffold for stem cell renewal

Research opens new avenues for understanding genetic basis of type 2 diabetes

TGen, Horizon Discovery partner in development of novel cancer cell-lines

New bioanalytical methods have potential for investigative and screening applications

Baker's yeast promising against cancer

GE Healthcare expands ecomagination product portfolio, adds Centricity Enterprise EMR solution

UCR purchases Nikon BioStation CT technology to assist in stem cell research

MV vaccine prevents TB in people with HIV infection

Researchers find three different degenerative brain disorders linked by toxic form of Elk-1 protein

Scientists are getting closer to prove how cholesterol causes heart disease

Repros Therapeutics receives FDA confirmation for initiating Androxal IND

Research shows DNA looping can impact gene expression

Study could provide potential therapeutic strategies for treating prostate cancer

Fluxion Biosciences to defend against alleged automated patch clamp system patent infringement lawsuit

Research suggests growth factor gene plays a central role in palate development

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

T Cell News and Research

Latest T Cell News and Research

Immunology eBook

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

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