Thrombosis News and Research

Latest Thrombosis News and Research

$Noninvasive fractional flow reserve still out of reach$

Noninvasive fractional flow reserve still out of reach

A novel, noninvasive approach to determining fractional flow reserve failed to show sufficient diagnostic accuracy to meet the primary endpoint of the DeFACTO trial, but was more accurate for diagnosing coronary artery ischemia than computed tomography, reported the trial’s lead investigator.

3 Sep 2012

Obesity no barrier to knee replacement surgery

Health policy should not withhold total knee arthroplasty from patients on the basis of obesity, say UK researchers.

3 Sep 2012

Potassium-channel autoimmunity linked to chronic pain

A substantial proportion of patients with voltage-gated potassium channel-complex autoimmunity experience chronic idiopathic pain, although the specific antigenic complex associated with pain remains to be determined, conclude US scientists.

3 Sep 2012

Some smaller clots may not require potentially risky treatment

Men and women who undergo joint replacement procedures, as well as those who have significant fractures, tend to be at an increased risk of developing pulmonary emboli (PE), blood clots that travel to the lungs where they may cause serious complications and even death.

1 Sep 2012

Doubt cast on LABA withdrawal in combination asthma therapy

Researchers have urged doctors to be cautious over withdrawal of long-acting beta-2 agonist therapy in patients with asthma controlled by this type of bronchodilator in combination with an inhaled corticosteroid, after finding the approach often results in destabilization of their condition.

31 Aug 2012

Mammographic density 'unrelated to breast cancer death risk'

Although high-density breast cancer high breast density on mammography is an established risk factor for developing breast cancer, it is not associated with an increased risk for death, say US investigators who suggest different factors may affect risk at different times.

31 Aug 2012

Promising results with SLIT for childhood grass pollen allergy

High-dose sublingual immunotherapy effectively reduces allergic symptoms and medication use in children with grass pollen–allergic rhinoconjunctivitis, show study results.

31 Aug 2012

French data highlight women under 60 at risk for heart disease

An analysis of four French registries has shown a dramatic drop in ST-segment-elevation myocardial infarction mortality from 1995 to 2010, accompanied by a significant change in patient characteristics.

31 Aug 2012

TNF inhibitors best cardiac option for psoriasis patients

Use of tumor necrosis factor inhibitors is associated with a significantly reduced risk for myocardial infarction in psoriasis patients compared with use of other medications, report researchers.

31 Aug 2012

Excessive daytime sleepiness during pregnancy should raise the alarm

Excessive daytime sleepiness is a common occurrence in pregnant women, particularly during the third trimester, but researchers warn that it might not always be physiologically normal.

31 Aug 2012

LCZ696 could be of PARAMOUNT importance in heart failure

The first-in-class angiotensin receptor neprilysin inhibitor LCZ696 could improve treatment of heart failure, report researchers who conducted a phase II trial of the drug and found it had superior results to an alternative therapy already in use.

31 Aug 2012

Tunes and T-shirts for cardiac rehabilitation

Two studies presented at the European Society of Cardiology Congress in Munich, Germany, showed how researchers are developing innovative approaches to help patients get the most out of cardiac rehabilitation.

31 Aug 2012

Sleep apnea’s contribution to diabetic nephropathy needs attention

The effect of obstructive sleep apnea syndrome on the development of diabetic nephropathy requires investigation, say researchers.

31 Aug 2012

Optimal cutoffs for defining pain in multiple sclerosis

A US study has identified optimal cutoffs for the definition of pain among individuals with multiple sclerosis.

30 Aug 2012

Emergency readmission after endoscopy linked to mortality risk

The risk for mortality is significantly increased among patients who are readmitted urgently following endoscopy, compared with other endoscopy patients, a UK study shows.

30 Aug 2012

Achievable outcomes focus of long-term postmenopausal weight loss

Research shows that successful long-term weight loss in postmenopausal women is associated with implementation of realistic and achievable dietary changes such as reducing consumption of sugar-sweetened drinks and desserts.

30 Aug 2012

Oral lesion progression markers validated, discovered

Loss of heterozygosity can reliably differentiate between individuals with premalignant oral lesions who are likely to progress to oral carcinoma, and those who are not, show study results.

30 Aug 2012

Sterotactic radiotherapy offers good results in recurrent head and neck cancer

For patients with recurring head and neck cancer, stereotactic body radiotherapy offers a feasible and tolerable salvage treatment, with median overall survival rates of more than 1 year, report researchers.

30 Aug 2012

Non-right-handedness increased in BD patients

Patients with bipolar disorder are around twice as likely to be non-right-handed as mentally healthy individuals, study results show.

30 Aug 2012

Closing in on neurologic biomarker diagnosis

A panel of five cerebrospinal fluid biomarkers may help doctors to accurately diagnose patients with various forms of dementia and parkinsonian disorders, research published in the Archives of Neurology suggests.

30 Aug 2012