Thrombosis News and Research

Latest Thrombosis News and Research

Lessons learned from transfusion refusal

Jehovah’s Witness patients who refuse blood transfusions during cardiac surgery are not at risk for surgical complications or long-term mortality compared with non-Witnesses who receive transfusions, report US researchers.

10 Jul 2012

Sleep studies essential before bariatric surgery

Obstructive sleep apnea frequently goes undiagnosed in obese patients who undergo bariatric surgery, show findings from a US study.

10 Jul 2012

Phase III darexaban results revealed

The direct oral factor Xa inhibitor darexaban is effective for the prevention of venous thromboembolism in Japanese patients undergoing major abdominal surgery, researchers find.

10 Jul 2012

Self-management of anticoagulants in elderly could be beneficial

Elderly patients who self-manage their oral anticoagulant treatment have a comparable treatment-related quality of life to those who undergo routine care, and may even experience higher treatment satisfaction, researchers say.

10 Jul 2012

Questionnaire may aid rheumatoid arthritis flare diagnosis

French researchers have created a 13-item patient-administered questionnaire for identifying a recent or present rheumatoid arthritis flare.

9 Jul 2012

Read-through molecule improves muscle function in DMD

A compound that results in a read-through on nonsense mutations in messenger RNA restores dystrophin expression in an animal model of Duchenne muscular dystrophy, research shows.

9 Jul 2012

Athletics-related injuries on increase in US adolescents

Injuries from athletic sports such as sprinting, long-distance running, and hurdles, are on the increase in children and adolescents, report US researchers.

9 Jul 2012

Complete subperichondrial rhinoplasty: A good tip for a good tip

A new and unconventional rhinoplasty technique minimizes soft tissue disruption, reducing bruising, edema, and numbness and making for a more speedy appearance of the final result, say researchers.

9 Jul 2012

Pioglitazone may raise bladder cancer risk

Study evidence supports a link between thiazolidinedione use, particularly pioglitazone, and bladder cancer in patients with Type 2 diabetes, Canadian researchers report.

9 Jul 2012

Home-based immunoglobulin therapy acceptable in primary immunodeficiency

Subcutaneous immunoglobulin therapy, administered at home, is an acceptable substitute for hospital-based intravenous immunoglobulin in patients with immune deficiencies, according to recent findings published in the Journal of Clinical Immunology.

9 Jul 2012

Prediction tool indicates prognosis after cardiac arrest

US researchers report the development of a prediction tool that could help determine neurologic prognosis after in-hospital cardiac arrest.

9 Jul 2012

Alcoholic hepatitis linked to hepatitis C risk

Hepatitis C virus is more common in patients with alcoholic hepatitis than the general population, but infections may be going undetected, US data show.

9 Jul 2012

Childbearing may reduce mortality in later life

All-cause mortality rates fall progressively among women aged 60–76 years the more children they have borne, show Australian study results.

9 Jul 2012

JRD receives FDA priority review designation for XARELTO sNDAs to treat PE, DVT

Janssen Research & Development, LLC (Janssen R&D) announced today the U.S. Food and Drug Administration (FDA) has assigned a priority review designation to the supplemental New Drug Applications (sNDAs) filed on May 2, 2012 for XARELTO (rivaroxaban), an oral anticoagulant, seeking new indications to treat patients with deep vein thrombosis (DVT), pulmonary embolism (PE), and to prevent recurrent DVT and PE.

9 Jul 2012

Novel biomimetic strategy can dissolve blood clots before they cause serious damage or even death

Researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard University have developed a novel biomimetic strategy that delivers life-saving nanotherapeutics directly to obstructed blood vessels, dissolving blood clots before they cause serious damage or even death.

6 Jul 2012

TMC receives NIH grant to evaluate pepducin in heart disease patients

Tufts Medical Center researchers are developing a first-of-its-kind drug to prevent deadly blood clots in heart disease patients, without the risk of serious bleeding associated with current medications. The National Heart, Lung, and Blood Institute of the National Institutes of Health has just awarded the team led by Athan Kuliopulos, MD, PhD, a $10 million grant to start testing a drug based on this novel technology.

4 Jul 2012