Thrombosis News and Research

Latest Thrombosis News and Research

Fat: An active player in the regulation of many processes in health and disease

Why should we be interested in doing obesity-related research? Emphasis is put on this type of research simply because of the fact that the epidemiological data and predictions are alarming. Worldwide it is estimated that one person in every eight is overweight and more than 300 millions are obese

3 Sep 2007

OPTIMIST: The Outcome of PCI for stent-ThrombosIs MultIcentre STudy

Stent thrombosis is a recognized complication occurring in 1-2% of patients with coronary artery disease treated by percutaneous coronary intervention (PCI) with stent implantation. Its occurrence is expected to increase with the number of stent implantation procedures done worldwide. Moreover, stent thrombosis is a hot topic in the cardiology community.

3 Sep 2007

Genetic-based dosing in orthopedic patients beginning warfarin therapy

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients. But now the process can be faster and safer, thanks to research conducted at Washington University School of Medicine in St. Louis.

3 Sep 2007

The goals of platelet inhibition in acute coronary syndromes

Platelet activation and aggregation play important roles in the pathogenesis of cardiac ischemic events after either spontaneous plaque disruption in acute coronary syndromes or mechanical disruption of coronary artery plaques caused by percutaneous coronary intervention (PCI), which could be considered an artificially induced acute coronary syndrome.

3 Sep 2007

Left main stem angioplasty

The left main coronary artery supplies at least two thirds of the hearts blood supply. When it becomes narrowed it causes large areas of the heart to malfunction with subsequent severe anginal chest pain and breathlessness. Occlusion of the left main coronary is usually fatal within a matter of seconds.

3 Sep 2007

DES: friend or foe?

The current FDA approved stents (CYPHER and TAXUS) have been associated with late stent thrombosis (LST) (>30days following implantation) however, the mechanisms predictive of LST are poorly understood. Pathologic studies are one of the best methods for detailed analysis of morphologic changes that occur after placement of Drug Eluting Stents to determine the causes of LST.

3 Sep 2007

Sex steroids, platelet aggregation and inflammation

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein. Despite the fact that the disorder is rare, it increases exponentially during menopause and can be deadly.

11 Aug 2007

New approach to assessing clot risk in menopausal women

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein.

9 Aug 2007

Prophylaxis effective at preventing joint bleeds and preserving joint function and structure in young boys with hemophilia A

According to a new landmark study published in The New England Journal of Medicine, infusions of clotting factor VIII used preventively can significantly reduce the risk of developing joint damage associated with joint bleeding in young children with hemophilia A.

9 Aug 2007

Discussion on the explosive growth and the potential risks of drug-eluting stents

The Summer 2007 issue of The American Heart Hospital Journal explores one of the pivotal issues in cardiology, the drug-eluting stent (DES).

9 Aug 2007

Jump in cancer-related clots

Blood clots are increasingly common in cancer patients, but University of Rochester Medical Center researchers have created a novel risk model that can predict, with 98 percent certainty, which patients will not get a blood clot.

3 Aug 2007

New hope for aortic dissection survivors

Each year, 10,000 Americans suffer a sudden tear in the lining of their body's largest blood vessel, the aorta.

26 Jul 2007

Studies assess blood clot prevalence outside hospital prevention in hospital

More cases of venous thromboembolism are diagnosed in the three months following hospitalization than during hospitalization, but less than half of inpatients receive medications to prevent blood clots from occurring, according to a report in the July 23 issue of Archives of Internal Medicine.

24 Jul 2007

FDA panel will help decide fate of drug Evista for preventing breast cancer

Before the osteoporosis drug Evista is approved for breast cancer in the U.S. the Food and Drug Administration (FDA) will take the advice of an advisory panel.

23 Jul 2007

Computers pass dosage test for thrombosis drugs

The largest ever study into the administration of blood thinning drugs like Warfarin has concluded that dosages calculated by computer are at least as safe and reliable as those provided by trained medical professionals.

From The University of Manchester 20 Jul 2007

Venous thromboembolism in the U.S.

Venous thrombosis (VTE), the formation of blood clots in a vein, is a major health problem for hospitalized patients in the United States.

16 Jul 2007

Barr confirms patent challenge of Aggrenox

Barr Pharmaceuticals, Inc. has confirmed that its subsidiary, Barr Laboratories, Inc., has initiated a challenge of the patent listed by Boehringer Ingelheim in connection with its Aggrenox Aspirin/Extended- Release Dipyridamole) 25 mg/200 mg capsules.

13 Jul 2007

Four hours in ecomony class doubles the risk for deep vein thrombosis

According to the World Health Organization (WHO) the chances of developing deep vein thrombosis ( DVT) double after traveling for four hours or more; this says WHO equates to one in 6,000 long-haul passengers at risk of potentially dangerous blood clots.

2 Jul 2007