Thrombosis News and Research

Latest Thrombosis News and Research

Growth in opioid use prompts safety concerns

Prescriptions for opioid drugs have increased significantly in Germany over the past decade, a survey of insurance data has found.

20 Feb 2013

AMD risk alleles fail to predict treatment response

The major risk alleles that influence the development of age-related macular degeneration do not predict response to therapy for the condition, a substudy of the CATT trial indicates.

20 Feb 2013

Misconduct biased fluid resuscitation studies

There are “serious safety concerns” associated with the use of hydroxyethyl starch for fluid resuscitation in critically ill patients, say the authors of a meta-analysis in JAMA.

20 Feb 2013

‘Liver first’ approach first choice for metastatic rectal cancer

Using the “liver first” approach to treat locally advanced rectal cancer and synchronous liver metastases allows nearly three-quarters of patients to receive optimal neoadjuvant therapy and resection for both their primary tumor and metastases, researchers report.

20 Feb 2013

Optimal lung cancer screening nodule size questioned

Researchers challenge the definition of a positive result in first-round lung cancer screening with low-dose computed tomography in the Annals of Internal Medicine.

19 Feb 2013

Severe childhood asthma blood test hopes dashed

Blood eosinophil counts do not reliably reflect airway eosinophil concentrations in children with severe, therapy-resistant asthma, and therefore cannot be used to make therapeutic decisions, researchers report.

19 Feb 2013

Oblique split graft technique avoids rhinoplasty warp

A novel graft technique may reduce the risk of costal cartilage graft warping in patients undergoing septorhinoplasty for saddle nose deformity with depleted source, Turkish surgeons say.

19 Feb 2013

Piroxicam ultrasound combination optimal for knee osteoarthritis

Phonophoresis of the non steroidal anti-inflammatory drug piroxicam with ultrasound is more effective than ultrasound alone for improving pain and other symptoms of mild-to-moderate knee osteoarthritis, show study findings.

19 Feb 2013

Clonal evolution explains unpredictable leukemia disease course

Scientists have revealed the complicated clonal evolution of chronic lymphocytic leukemia, giving insight into the variation in disease course and its response to treatment.

19 Feb 2013

Findings add weight to WHO malaria pregnancy guidance

Pregnant women who receive three or more doses of malaria preventive therapy have higher birthweight babies than those who only receive two, conclude the authors of a meta-analysis.

18 Feb 2013

Insights into HIV-1 virion makeup could improve gene therapy

A discovery about how the HIV-1 virion packages genomic RNA may help researchers to improve the efficacy of gene therapy.

18 Feb 2013

Dance-related injuries in young people on the increase

Findings spanning 17 years suggest that dance-related injuries in children and adolescents in the USA have increased by 37% over this time.

18 Feb 2013

Clot evacuation reduces perihematomal edema in hemorrhagic stroke

Minimally invasive surgery combined with recombinant tissue-type plasminogen activator significantly reduces perihematomal edema in patients with intracerebral hemorrhage.

18 Feb 2013

Early PBC prognosis advocated

Biochemical response to ursodeoxycholic acid at 6 months is a better predictor for primary biliary cirrhosis prognosis than the current standard of 1 year, study results suggest.

18 Feb 2013

Copper depletion may prevent breast cancer recurrence

Early trial findings suggest that copper depletion may promote tumor dormancy in patients at high risk for recurrent breast cancer.

18 Feb 2013

Age not a major factor in asthma allergic sensitization rates

Results from a US study suggest that there is no significant difference in allergic sensitization rates between younger and older patients with asthma.

18 Feb 2013

Earlier may be better for neurostimulation in Parkinson’s

Adding neurostimulation to best medical therapy boosts quality of life in patients with relatively early-stage Parkinson’s disease, shows a randomized trial.

18 Feb 2013

Antibody test ‘inappropriate’ without connective tissue symptoms

The positive antinuclear antibody test is often used inappropriately in patients without indications of connective tissue disease, real-world research suggests.

18 Feb 2013

rEVO Biologics announces results from Atryn phase 3 studies on pregnant AT-deficient women

rEVO Biologics announced today the results of a major retrospective study analysis of its pivotal phase 3 studies which demonstrate that pregnant patients with hereditary antithrombin deficiency (HD) benefit from ATryn Antithrombin (Recombinant) therapy to prevent venous thromboembolic events (VTE).

16 Feb 2013

FDA approves Novartis’ Zortress to prevent organ rejection after liver transplantation in adults

Novartis announced today that the US Food and Drug Administration (FDA) has approved Zortress (everolimus) for the prophylaxis of organ rejection in adult patients receiving a liver transplant.

16 Feb 2013