Toxicology

Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.

What is Toxicology?

Toxicology is the scientific study of adverse effects that occur in living organisms due to chemicals. It involves observing and reporting symptoms, mechanisms, detection and treatments of toxic substances, in particular relation to the poisoning of humans.

Toxicity of Metabolites

What is Toxicogenomics?

Glyphosate in Food: How Dangerous is it?

Validating the In-Silico Model for Toxicity Studies

What is In Silico Toxicology?

Latest Toxicology News and Research

Potential antibody treatment for yellow fever developed in 7 months using Rapid Response Strategy

Yellow fever, an acute viral hemorrhagic disease transmitted by infected mosquitoes, infects about 200,000 people and causes an estimated 30,000 deaths each year.

5 Aug 2020

Research reveals microplastic content levels in Australian seafood

Levels of plastic contamination have been found in samples of popular seafood such as prawns, oysters, and crabs, with the highest content found in sardines, according to University of Queensland research.

4 Aug 2020

Researchers develop efficient and more sensitive method to test heavy metals in foods and water

Finding out if the food and water we consume are safe from toxic and carcinogenic metals can now be much faster and simpler.

4 Aug 2020

Konstanz biologists receive Ursula M. Händel Animal Welfare Prize

Marcel Leist, Professor of In-Vitro Toxicology and Biomedicine at the University of Konstanz, and Thomas Hartung, Professor of Environmental Health Sciences at the University of Konstanz and Doerenkamp-Zbinden Chair of Evidence-Based Toxicology at Johns Hopkins Bloomberg School of Public Health in Baltimore, have been awarded the Ursula M. Händel Animal Welfare Prize 2020 of the German Research Foundation.

31 Jul 2020

Scientists examine how glyphosate exposure affects reproduction

Exposure to the chemical glyphosate changed the level of some ovarian proteins in mice but did not impact ovarian steroid production, an indication glyphosate may not adversely affect reproduction, according to a new study.

28 Jul 2020

Study shows how mast cells regulate calcium levels to control the immune response

Instead of protecting us, the immune system can sometimes go awry, as in the case of autoimmune diseases and allergies. An Ludwig-Maximilian-Universitaet (LMU) in Munich team has dissected how mast cells regulate their calcium levels to keep the immune response under control.

23 Jul 2020

C-Path gets positive response from FDA for drug-induced skeletal muscle injury safety biomarkers

Critical Path Institute announced today that the Biomarker Qualification Program at the Center for Drug Evaluation and Research in the U.S. Food and Drug Administration issued a positive response to the Letter of Intent developed by C-Path's Predictive Safety Testing Consortium and Duchenne Regulatory Science Consortium, for a panel of four safety biomarkers of acute drug-induced skeletal muscle injury.

23 Jul 2020

Sex lives of leeches can shed light on endocrine disrupting chemicals

Today, we pull the veil back on the secret sex lives of leeches and how researchers at McMaster University and Fisheries and Oceans Canada are using that information to learn about endocrine disrupting chemicals.

21 Jul 2020

UC Davis Health evaluates new antibody cocktail as a possible treatment for COVID-19

Timothy Albertson, chair of internal medicine and specialist in pulmonary and critical care, is leading efforts at UC Davis Health to test a new antibody cocktail (REGN-COV2) as a prevention and treatment for COVID-19.

20 Jul 2020

Study could help develop new drugs for toxoplasma infection

Researchers at Indiana University School of Medicine have discovered new information about how a dangerous parasite takes control of a patient's cells as it spreads throughout their body, an important finding that could help in the development of new drugs to treat this infection.

17 Jul 2020

UTHSC researchers receive $2.4 million to study the role of cholesterol in brain artery health

Alex Dopico, MD, PhD, professor and Van Vleet Chair of Excellence in the Department of Pharmacology, Addiction Science, and Toxicology, and Anna Bukiya, PhD, associate professor in the Department of Pharmacology, Addiction Science, and Toxicology, have been awarded $2.4 million from the National Heart, Lung, and Blood Institute to explore how cholesterol interacts with the mechanisms that modulate blood vessel function in the brain.

16 Jul 2020

Insilico Medicine, Arctoris announce technology partnership to discover new COVID-19 drugs

Insilico Medicine, a biotechnology company developing an end-to-end drug discovery pipeline utilizing next-generation artificial intelligence, today announced a technology partnership with Arctoris, the world's first fully automated drug discovery platform, offering remotely accessible, pre-optimized and fully validated R&D processes for its partners and clients globally.

9 Jul 2020

Zebrafish study finds few health impacts of 5G wireless technology

Findings from an Oregon State University study into the effects of radiofrequency radiation generated by the wireless technology that will soon be the standard for cell phones suggest few health impacts.

8 Jul 2020

Unique nanoparticle can reduce side effects, increase the effectiveness of cancer treatment

A unique nanoparticle to deliver a localized cancer treatment inhibits tumor growth in mice, according to a team of Penn State researchers.

8 Jul 2020

Scientists identify compounds that block replication of COVID-19 virus

As the death toll from the COVID-19 pandemic mounts, scientists worldwide continue their push to develop effective treatments and a vaccine for the highly contagious respiratory virus.

7 Jul 2020

Study reveals the role of glucocorticoid metabolism and GILZ regulation during aging

Why do we age? What exactly is happening in our bodies? And can we do anything about it? Mankind has sought answers to these questions since time immemorial.

1 Jul 2020

'Mini-brains' can be infected by SARS-CoV-2 virus

A multidisciplinary team from two Johns Hopkins University institutions, including neurotoxicologists and virologists from the Bloomberg School of Public Health and infectious disease specialists from the school of medicine, has found that organoids (tiny tissue cultures made from human cells that simulate whole organs) known as "mini-brains" can be infected by the SARS-CoV-2 virus that causes COVID-19.

30 Jun 2020

Researchers discover receptor that makes mice strong and slim

Increasing abdominal girth and shrinking muscles are two common side effects of aging. Researchers at the University of Bonn have discovered a receptor in mice that regulates both effects.

25 Jun 2020

Neuroscientists shed new light on mechanisms responsible for familial migraine

Neuroscientists of the University of Zurich shed a new light on the mechanisms responsible for familial migraine: They show that a genetic dysfunction in specific brain cells of the cingulate cortex area strongly influences head pain occurrence.

24 Jun 2020

Penn’s CEET receives $8 million grant for environmental health research

The Center of Excellence in Environmental Toxicology at the University of Pennsylvania received an $8 million grant, to be distributed over the next five years, from the National Institute of Environmental Health Sciences, a renewal of its P30 Environmental Health Sciences Core Center grant.

17 Jun 2020

Toxicology

Overview

Toxicity of Metabolites

What is Toxicogenomics?

Glyphosate in Food: How Dangerous is it?

Feature Articles

Validating the In-Silico Model for Toxicity Studies

What is In Silico Toxicology?

Latest Toxicology News and Research

Potential antibody treatment for yellow fever developed in 7 months using Rapid Response Strategy

Research reveals microplastic content levels in Australian seafood

Researchers develop efficient and more sensitive method to test heavy metals in foods and water

Konstanz biologists receive Ursula M. Händel Animal Welfare Prize

Scientists examine how glyphosate exposure affects reproduction

Study shows how mast cells regulate calcium levels to control the immune response

C-Path gets positive response from FDA for drug-induced skeletal muscle injury safety biomarkers

Sex lives of leeches can shed light on endocrine disrupting chemicals

UC Davis Health evaluates new antibody cocktail as a possible treatment for COVID-19

Study could help develop new drugs for toxoplasma infection

UTHSC researchers receive $2.4 million to study the role of cholesterol in brain artery health

Insilico Medicine, Arctoris announce technology partnership to discover new COVID-19 drugs

Zebrafish study finds few health impacts of 5G wireless technology

Unique nanoparticle can reduce side effects, increase the effectiveness of cancer treatment

Scientists identify compounds that block replication of COVID-19 virus

Study reveals the role of glucocorticoid metabolism and GILZ regulation during aging

'Mini-brains' can be infected by SARS-CoV-2 virus

Researchers discover receptor that makes mice strong and slim

Neuroscientists shed new light on mechanisms responsible for familial migraine

Penn’s CEET receives $8 million grant for environmental health research

Screening for pancreatic cancer using artificial intelligence

Is medication exposing us to hormone-disrupting chemicals?

Developing a Better Understanding of Polycystic Ovary Syndrome (PCOS)

Toxicology

Overview

Feature Articles

Validating the In-Silico Model for Toxicity Studies

What is In Silico Toxicology?

Latest Toxicology News and Research

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