Toxicology

Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.

What is Toxicology?

Toxicology is the scientific study of adverse effects that occur in living organisms due to chemicals.

Glyphosate in Food: How Dangerous is it?

Validating the In-Silico Model for Toxicity Studies

Latest Toxicology News and Research

COPD: Ion channels in immune cells could potentially be targets for new therapies

Chronic obstructive pulmonary disease – COPD for short – is one of the most common diseases of the lung. It affects almost 300 million people worldwide, of which about three million die every year.

17 Jan 2022

Newly designed biochip simplifies the process of manufacturing in vitro skin in the laboratory

Researchers from the Universidad Carlos III de Madrid, the Universidad Politécnica de Madrid (UPM) and other entities have designed a new biochip, a device that simplifies the process of manufacturing in vitro skin in the laboratory and other complex multi-layer tissues.

12 Jan 2022

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Northwestern Medicine investigators have discovered a novel mechanism linking an intercellular adhesion molecule with genetic inflammatory skin diseases, according to findings published in the Journal of Clinical Investigation.

11 Jan 2022

Vaccinated mothers transfer SARS-CoV-2 antibodies to their breastfed infants

Women vaccinated against COVID-19 transfer SARS-CoV-2 antibodies to their breastfed infants, potentially giving their babies passive immunity against the coronavirus, according to University of Massachusetts Amherst research.

7 Jan 2022

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Drug-induced liver injury (DILI) is an adverse reaction to ingesting a drug, which can appear both in developmental stages, in their clinical use and even after being approved as a drug.

30 Dec 2021

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

A gene that is overexpressed in some aggressive cancers also appears to be key to the excessive cell proliferation that thickens the walls of pulmonary arteries and ultimately causes the right ventricle of the heart to fail, scientists report.

16 Dec 2021

Study details the effectiveness of face masks to reduce the spread of respiratory infections

Findings from a new study published today provide guidance for increasing the effectiveness of face masks to reduce the spread of respiratory infectious pathogens including SARS-CoV-2. T

16 Dec 2021

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

A diet rich in plant products reduces the risk of cognitive impairment and dementia in the elderly. This is the result of a study by the Biomarkers and Nutritional Food Metabolomics Research Group of the Faculty of Pharmacy and Food Sciences of the University of Barcelona and the CIBER on Frailty and Healthy Aging.

9 Dec 2021

Targeting the brain should be the focus of ALS therapy, not just spinal cord

The brain is indeed a target for treating ALS (amyotrophic lateral sclerosis), Northwestern Medicine scientists have discovered.

4 Dec 2021

Method can help identify proteins in the body affected by chemicals

How do pollutants and other chemicals that we are exposed to affect our health? Researchers from Linköping University, Sweden, have applied a method to identify the proteins in the body affected by chemicals.

25 Nov 2021

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

The Institute of Human Virology (IHV) at the University of Maryland School of Medicine and MitoPower LLC were awarded an SBIR (Small Business Innovation Research) grant of up to $6.5 million over five years from the National Institutes of Health's National Institute on Alcohol Abuse and Alcoholism.

9 Nov 2021

Therapeutics that target ceramides may help treat cardiometabolic disease

Therapeutics that target lipids called ceramides might hold potential for treating cardiometabolic disease, argues a review article published November 5th in the journal Trends in Pharmacological Sciences.

7 Nov 2021

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Polybrominated diphenyl ethers, or PBDEs, are a class of fire-retardant chemicals that are ubiquitous. They are found on upholstery, carpets, curtains, electronics, and even infant products.

7 Nov 2021

Research could lead to new methods for tracking COVID-19

The last issue of Wiley's Research Headlines highlighted part one of a study in Environmental Toxicology and Chemistry that involved analysis of sludge from a wastewater treatment plant in Connecticut, and revealed trends in levels of chemicals such as pharmaceuticals and drugs during the first wave of the COVID-19 pandemic.

3 Nov 2021

Innovative in vitro platform to evaluate the cardiotoxicity of chemicals

People are continuously exposed to a huge amount and variety of potentially toxic chemicals present in the surrounding environment, such as pesticides or drugs traces in water, soil, air and living organisms. The combined action of pollutants can increase the risk of toxic effects.

25 Oct 2021

Public and environmental health effects of the pandemic revealed by chemical analyses of wastewater

When investigators analyzed primary sludge collected during the first wave of COVID-19 (March 19 to June 30, 2020) at a wastewater treatment plant in Connecticut, they found trends in the presence of chemicals that related directly to the pandemic-;for example, hydroxychloroquine had elevated concentrations in the week following Emergency Use Authorization of the drug for the treatment of COVID-19.

20 Oct 2021

Zinc oxide in sunscreens destroys UVA protection during sun exposure

During use some sunscreens offer very limited protection against dangerous sunrays and may even be harmful.

15 Oct 2021

A mucoadhesive polymer with anti-SARS-COV-2 activity in vitro and in vivo

The team has evaluated a low molecular weight chitosan derivative as a candidate preventing the viral entry into mammalian nasal epithelial cells to limit the spread of COVID-19.

12 Oct 2021

Accumulation of amyloid beta and reduction of serotonin may trigger late-life depression

Looking for ways to image the human brain for the earliest signs of aging and cognitive decline, Johns Hopkins Medicine researchers recently identified a pattern that links the accumulation of amyloid beta (Aβ) proteins (associated with cognitive decline later in life) with a reduction of serotonin, the brain chemical that improves mood.

7 Oct 2021

Thousands of unknown chemicals and substances found in e-cigarettes

Vaping aerosols contain thousands of unknown chemicals and substances not disclosed by manufacturers, including industrial chemicals and caffeine, Johns Hopkins University researchers found.

6 Oct 2021

Toxicology

Overview

Toxicity of Metabolites

What is Toxicogenomics?

Glyphosate in Food: How Dangerous is it?

Feature Articles

Validating the In-Silico Model for Toxicity Studies

What is In Silico Toxicology?

Latest Toxicology News and Research

COPD: Ion channels in immune cells could potentially be targets for new therapies

Newly designed biochip simplifies the process of manufacturing in vitro skin in the laboratory

Novel mechanism linking intercellular adhesion molecule with genetic skin diseases discovered

Vaccinated mothers transfer SARS-CoV-2 antibodies to their breastfed infants

Study uses metabolomics to discriminate drug-induced liver injury phenotypes

Gene key to excessive cell proliferation could be a potential target for fatal pulmonary hypertension

Study details the effectiveness of face masks to reduce the spread of respiratory infections

Higher intake of plant-based foods could help reduce the risk of cognitive decline due to aging

Targeting the brain should be the focus of ALS therapy, not just spinal cord

Method can help identify proteins in the body affected by chemicals

SBIR grant awarded to develop treatment for alcoholic liver disease-associated hepatorenal syndrome

Therapeutics that target ceramides may help treat cardiometabolic disease

Maternal exposure to flame retardants linked with ASD-relevant behavioral traits in offspring

Research could lead to new methods for tracking COVID-19

Innovative in vitro platform to evaluate the cardiotoxicity of chemicals

Public and environmental health effects of the pandemic revealed by chemical analyses of wastewater

Zinc oxide in sunscreens destroys UVA protection during sun exposure

A mucoadhesive polymer with anti-SARS-COV-2 activity in vitro and in vivo

Accumulation of amyloid beta and reduction of serotonin may trigger late-life depression

Thousands of unknown chemicals and substances found in e-cigarettes

How has COVID-19 Impacted our Economy?

Using lab-grown stomachs to shed light on the symptoms of COVID-19

Developing a 'Fingerprint' test that could diagnose Alzheimer’s early

Toxicology

Overview

Feature Articles

Validating the In-Silico Model for Toxicity Studies

What is In Silico Toxicology?

Latest Toxicology News and Research

Newsletters you may be interested in