Toxicology

Toxicology is the study of harmful interactions between chemical, physical, or biological agents and biological systems.

Health Implications of p‑Phenylenediamine: The Aromatic Amine in Permanent Hair Dye

Uncover the risks and realities of a key hair dye ingredient as science, safety, and regulation collide in the quest for perfect color.

Glyphosate in Food: How Dangerous is it?

Bisphenol A (BPA): The FDA's Position

The Role of Toxicology in Wildlife Conservation

Validating the In-Silico Model for Toxicity Studies

Latest Toxicology News and Research

Fentanyl abuse impairs cardiac cell function and contributes to heart rhythm defects

In recent years, fentanyl, a synthetic opioid that is 50 to 100 times stronger than morphine, has been a main contributor to the opioid crisis.

28 Aug 2025

Killifish study reveals multi-generational impacts of exposure to crude oil and flame retardants

A tiny fish with transparent embryos is helping University of California, Davis, researchers shed light on how exposure to crude oil and flame retardants can affect behavior, skeletal growth, cardiac health and other internal functions in offspring and subsequent generations.

28 Aug 2025

Investigating toxicity of common bisphenol replacements in food packaging

Chemicals used to replace bisphenol A (BPA) in food packaging can trigger potentially harmful effects in human ovarian cells, according to McGill University researchers.

26 Aug 2025

Excess deaths in Maui highlight hidden impact of wildfires

New research unveils the true death toll of the deadly August 2023 wildfires which took place in Lāhainā, Maui, Hawaiʻi - and which temporarily made wildfire a leading cause of death in Maui.

25 Aug 2025

AI predicts designer drug structures for improved detection

How does one identify something no one has a test for? Designer drugs replicate the effects of known, illicit drugs but evade law enforcement. The chemical structure variations that help these compounds avoid detection also make them unpredictable in the body - a quality that poses serious health consequences.

21 Aug 2025

Heated herbal product delivers nicotine with fewer toxins

Research on the iSENZIA™ system shows it provides nicotine with significantly lower harmful chemicals, highlighting its tobacco harm reduction potential.

18 Aug 2025

PFAS exposure increases risk of weight regain after adolescent bariatric surgery

Adolescents who undergo bariatric surgery face a higher risk of weight regain, which can undermine treatment success and long-term health, if they have elevated blood levels of per- and polyfluoroalkyl substances (PFAS) prior to the procedure, according to new USC research.

14 Aug 2025

Natural gut molecule reverses liver damage and repairs gut lining

UC Davis Health researchers have discovered that a natural molecule made by gut bacteria can reverse liver damage and repair the gut lining after aflatoxin exposure.

12 Aug 2025

VCU Massey pioneers clinical trial of novel GGT-1 inhibitor PTX-100

VCU Massey Comprehensive Cancer Center is the first site in the United States to be activated in a global Phase 2a clinical trial evaluating PTX-100 (AKA GGTI-2418), a first-in-class small molecule inhibitor of geranylgeranyl transferase-1 (GGT-1), for the treatment of cutaneous T-cell lymphoma (CTCL), a rare and often treatment-resistant T-cell lymphoma.

26 Jul 2025

Agricultural dust exposure may pose significant risks to gut health

Inhaling agricultural dust may pose significant risks to gut health for workers in animal agriculture, a University of California, Riverside, study has found.

18 Jul 2025

Lead exposure in early life linked to faster memory loss in children

A study led by researchers at the Icahn School of Medicine at Mount Sinai shows that exposure to lead during pregnancy and early childhood may accelerate the rate at which children forget information-a critical marker of memory impairment that may have implications for learning and development.

9 Jul 2025

Multi-contaminant water treatment could prevent tens of thousands of cancer cases

Drinking water treatment that pursues a multi-contaminant approach, tackling several pollutants at once, could prevent more than 50,000 lifetime cancer cases in the U.S., finds a new peer-reviewed study by the Environmental Working Group.

8 Jul 2025

Early life exposure to PFHxA may impact male brain development

"Forever chemicals" or per- and polyfluoroalkyl substances (PFAS) have been widely used in consumer and industrial products for the better part of a century, but do not break down in the natural environment.

4 Jul 2025

EU researchers call for wider use of alternatives to animal testing

Researchers examine how the use of animal testing to identify endocrine-disrupting substances in the EU can be reduced. Although it is, in principle, possible to identify such substances without using animals, non-animal methods are still rarely applied.

3 Jul 2025

‘MAHA Report’ calls for fighting chronic disease, but Trump and Kennedy have yanked funding

‘MAHA report’ calls for fighting chronic disease, but Trump and Kennedy have yanked funding

2 Jul 2025

Researchers find gut bacteria rapidly soak up ‘forever chemicals’

Scientists have demonstrated that select human gut bacteria can bioaccumulate and sequester PFAS ‘forever chemicals’, increasing faecal excretion in humanized mice. The findings reveal a potential microbiome-based strategy to reduce PFAS body burden, though clinical benefit in humans remains unproven.

1 Jul 2025

Disposable vapes found to emit more toxic metals than traditional cigarettes

They may look like travel shampoo bottles and smell like bubblegum, but after a few hundred puffs, some disposable, electronic cigarettes and vape pods release higher amounts of toxic metals than older e-cigarettes and traditional cigarettes, according to a study from the University of California, Davis.

25 Jun 2025

Synthetic opioids and designer benzodiazepines linked to driving impairment

No-one could claim to be unaware of the dangers of driving under the influence of drugs (DUID): drugs can increase the time needed to react, impair coordination, alertness, and cognition, and lower inhibitions, thus encouraging reckless and aggressive driving.

25 Jun 2025

Scaling 3D biology: Automation, imaging, and the future of high-throughput research

Discover how 3D biology, automation, and AI are revolutionizing drug discovery, improving predictive accuracy, and accelerating research.

From Molecular Devices UK Ltd 12 Jun 2025

Mount Sinai receives NIH grant to study overdoses linked to synthetic opioids

The Icahn School of Medicine at Mount Sinai has been awarded a $3.8 million grant from the National Institute on Drug Abuse, a division of the National Institutes of Health, to study drug overdose cases linked to novel synthetic opioids.

10 Jun 2025