Tuberculosis News and Research

Latest Tuberculosis News and Research

Prior parasitic worm infections may complicate TB therapy

Tuberculosis (TB) is a major threat to global health, taking the lives of more than a million people worldwide each year. Its greatest impact is often in the most impoverished places on earth, where patients frequently suffer from multiple chronic illnesses at the same time. In such situations, the question of whether each individual illness might make concurrent illnesses more difficult to treat becomes a critical issue both for specific patients and for general public health.

19 Aug 2011

MSF warns global shortage of drug-resistant TB treatment likely

As countries increase the use of the GeneXpert test, a two-hour molecular TB test released in 2010, "enabl[ing] them to diagnose more patients with drug-resistant tuberculosis (DR-TB), a worldwide shortage of the drugs to treat these patients is likely, Medecins Sans Frontieres (MSF) warns," according to PlusNews.

18 Aug 2011

Bayer Healthcare to provide over 600,000 moxifloxacin tablets to fight MDR-TB in China

Bayer Healthcare announced on Monday it "has agreed to support the World Health Organization (WHO) and the Stop TB Partnership in the fight against multidrug-resistant tuberculosis (MDR-TB) by making 620,000 tablets of the antibiotic moxifloxacin available to WHO," according to a Bayer press release.

17 Aug 2011

Methodist, Philips partner to develop new imaging technology for infectious diseases

The Methodist Hospital Research Institute and Philips Healthcare are collaborating to develop new imaging technology that could be used to help identify the start -- and cause -- of an infectious disease epidemic.

From Philips Healthcare 17 Aug 2011

Inexpensive microcalorimeters can quickly detect TB

Researchers have discovered a faster, cheaper method for the diagnosis of tuberculosis (TB). A major barrier in TB prevention, especially in developing countries, is that diagnosis is slow and costly.

17 Aug 2011

Bird malaria in Britain worries experts

British birds are being increasingly detected with malaria. Two decades back few British species showed regular signs of infection but now some 30 types are infected, monitoring projects have found. The problem is linked to a rapid growth in mosquito populations, which is attributed to a rise of about 1 degrees centigrade in global average temperature, say experts.

15 Aug 2011

Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis

For nearly 60 years, Pyrazinamide (PZA) has been used in conjunction with other medications to treat tuberculosis (TB), but scientists did not fully understand how the drug killed TB bacteria. PZA plays a unique role in shortening the duration of current TB therapy to six months and is used frequently to treat multi-drug resistant TB.

12 Aug 2011

Alternatives needed to inaccurate blood tests used to diagnose active TB

A guest post in PLoS Medicine's "Speaking of Medicine" blog, written by tuberculosis (TB) researchers Madhukar Pai of McGill University, David Dowdy of the Johns Hopkins Bloomberg School of Public Health, and Karen Steingart of the University of Washington School of Public Health, examines the medical, public health and economic consequences of the widespread use of inaccurate antibody-based serological diagnostic tests for active TB.

12 Aug 2011

Researchers discover key reason why pyrazinamide shortens duration of TB therapy

Pyrazinamide has been used in combination with other drugs as a first-line treatment for people with tuberculosis (TB) since the 1950s, but exactly how the drug works has not been well understood.

12 Aug 2011

Researchers identify unknown link between migration of WBCs to infected tissues, immune memory

Researchers from Dr. Woodland's lab at the Trudeau Institute have now identified a previously unknown link between the migration of white blood cells to infected tissues and the ability of these cells to survive and become long-lived memory cells after the infection has been cleared.

11 Aug 2011

BCG vaccine can help immune system recognise cancer cells as 'foreign'

Scientists have found a potential new mechanism to stimulate the body's own ability to fight cancer using Baculillus Calmette-Guerin (BCG) - the germ commonly used to inoculate against tuberculosis.

11 Aug 2011

Commercial blood serum antibody tests cost-effective, not accurate for active TB

Commercial blood serum antibody tests—widely used in India and other developing countries to diagnose active tuberculosis—are not accurate or cost-effective, according to an analysis by researchers at the Johns Hopkins Bloomberg School of Public Health, the University of Washington School of Public Health and McGill University.

11 Aug 2011

CDC Director lauds India for TB and tobacco use control efforts, urges preparations to fight NCDs

CDC Director Thomas Frieden, who currently is visiting India and who previously worked with the Indian government assisting in tuberculosis (TB) control, praised the country's "progress in controlling tuberculosis and tobacco use" on Monday during a speech to health practitioners and policymakers, according to the Wall Street Journal's "India Real Time" blog.

11 Aug 2011

Aeras, OETC announce initiation of new TB vaccine Phase IIb trial in patients with HIV

Aeras and the Oxford-Emergent Tuberculosis Consortium (OETC) announce today the start of a Phase IIb proof-of-concept efficacy trial of a new investigational tuberculosis (TB) vaccine that involves people living with the human immunodeficiency virus.

11 Aug 2011

U.S. delegation in South Africa to renew bilateral relationship, create sustainable partnerships in health

This post on the Center for Strategic and International Studies's Commission on Smart Global Health Policy blog examines tuberculosis (TB) in South Africa, "which has the highest tuberculosis infection rate per population and accounts for 5 percent of the global TB burden."

10 Aug 2011

Vitamin D, UVB may help prevent dental caries

Large geographical variations in dental health and tooth loss among U.S. adolescents and young adults have been reported since the mid-1800s. The first study finding a north-south gradient in dental caries was a report of men rejected from the draft for the Civil War for lost teeth, from 8 per 1000 men in Kentucky to 25 in New England.

10 Aug 2011

Economic slowdown should not hamper global fund donations

With the new knowledge that providing antiretroviral treatment to people living with HIV would "contribut[e] to a sharp slowdown in the spread of the virus," "scaling up treatment now may prove to be the least expensive option if we want to bring this deadly pandemic, which still infects 1.8 million people every year, under control," Michel Kazatchkine, executive director of the Global Fund to Fight AIDS, Tuberculosis and Malaria writes in the Guardian's "Poverty Matters Blog."

6 Aug 2011

Lancet reports on Global Fund donors that have held back contributions

Several donors to the Global Fund to Fight AIDS, Tuberculosis and Malaria "continue to hold back their contributions for this year … adding up to more than $500 million that the Global Fund had been counting on for this year out of a total budget of about $3 billion," the Lancet reports.

6 Aug 2011

U.S. should demand human rights-based approach to HIV prevention programs in Uganda

"Uganda has sometimes been considered a success story in fighting HIV and has been a darling of international donors," including the U.S., which has poured over $1 billion into the country for AIDS programs.

6 Aug 2011

Akonni to develop closed amplicon RT-PCR microarray for virus detection in CSF

Akonni Biosystems, a molecular diagnostics company that develops novel nucleic acid extraction and microarray-based testing systems designed to rapidly and economically analyze biological samples, today announced receipt of a $300K grant from the National Institutes of Health.

5 Aug 2011

Tuberculosis News and Research

Latest Tuberculosis News and Research

Prior parasitic worm infections may complicate TB therapy

MSF warns global shortage of drug-resistant TB treatment likely

Bayer Healthcare to provide over 600,000 moxifloxacin tablets to fight MDR-TB in China

Methodist, Philips partner to develop new imaging technology for infectious diseases

Inexpensive microcalorimeters can quickly detect TB

Bird malaria in Britain worries experts

Pyrazinamide inhibits trans-translation in Mycobacterium tuberculosis

Alternatives needed to inaccurate blood tests used to diagnose active TB

Researchers discover key reason why pyrazinamide shortens duration of TB therapy

Researchers identify unknown link between migration of WBCs to infected tissues, immune memory

BCG vaccine can help immune system recognise cancer cells as 'foreign'

Commercial blood serum antibody tests cost-effective, not accurate for active TB

CDC Director lauds India for TB and tobacco use control efforts, urges preparations to fight NCDs

Aeras, OETC announce initiation of new TB vaccine Phase IIb trial in patients with HIV

U.S. delegation in South Africa to renew bilateral relationship, create sustainable partnerships in health

Vitamin D, UVB may help prevent dental caries

Economic slowdown should not hamper global fund donations

Lancet reports on Global Fund donors that have held back contributions

U.S. should demand human rights-based approach to HIV prevention programs in Uganda

Akonni to develop closed amplicon RT-PCR microarray for virus detection in CSF

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

Tuberculosis News and Research

Latest Tuberculosis News and Research

Synthetic Biology and the Pursuit of Living Diagnostics

Modular, Scalable, Intelligent: How n6 Is Rethinking NGS Library Prep

Evolving spectrophotometry for modern biopharma workflows

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