Von Hippel Lindau Syndrome

What is Von Hippel-Lindau Syndrome?

Von Hippel-Lindau syndrome (VHL) is a genetic disorder that is characterized by the growth of benign and malignancy tumors in the central nervous system (CNS) and viscera. This may include many different types of tumors, such haemangioblastomas, renal cell carcinoma (RCC) renal cysts and phaeochromocytoma.

Von Hippel Lindau Genetics

Treatment Strategies for Von-Hippel-Lindau Syndrome

Von Hippel-Lindau Syndrome Screening and Diagnosis

New massive sequencing platform implemented for double factor preimplantation genetic testing

A research team from the Universitat Autònoma de Barcelona, in collaboration with the Blood and Tissue Bank of Catalonia, has managed to implement a massive sequencing platform for Preimplantation Genetic Testing for the first time in history.

5 Dec 2018

Practicing with fake organs helps surgeon to perform complex cancer surgery

Anthony Camnetar remembers the first time he was told that he had von Hippel-Lindau syndrome, a rare genetic disorder.

7 Jun 2018

Stem cell lines are ideal research tools for designing models to understand disease progression

Scientists from King's College London have announced that 16 human embryonic stem (hES) cell lines have been approved by the US National Institutes of Health (NIH) and placed on their Stem Cell Registry, making them freely available for federally-funded research in the USA.

25 Sep 2013

A paradigm shift for targeted cancer therapy

We already know that recycling benefits our planet; and now new research suggests that the cellular version might be useful for battling cancer.

8 Jul 2008

Discovery of molecule that kills kidney cancer cells

Kidney cancer patients generally have one option for beating their disease: surgery to remove the organ. But that could change, thanks to a new molecule found by Stanford University School of Medicine researchers that kills kidney cancer cells. Ideally, the researchers said, a drug created from this molecule would help fight the life-threatening disease while leaving patients' kidneys intact.

7 Jul 2008

Hearing loss and von Hippel-Lindau disease

Patients with the genetic disorder von Hippel-Lindau disease may suddenly experience hearing loss because of a tumor-associated hemorrhage in the inner ear, according to a study in the July 4 issue of JAMA.

4 Jul 2007

Key mechanism identified by which the body regulates iron metabolism

Scientists at the University of California, San Diego (UCSD) have determined a key mechanism by which the body regulates iron metabolism, a discovery that may provide new approaches for the treatment of anemia.

23 Jun 2007

Cochlear implant restores hearing to patient with von Hippel-Lindau disease

Researchers at Georgetown University Medical Center and the National Institutes of Health (NIH) have, for the first time, used a bionic ear to restore hearing in a patient with von Hippel-Lindau disease.

8 Jun 2007

Loss of a single gene in kidney cancer cells causes them to stop making mitochondria

Studying a rare inherited syndrome, researchers at Johns Hopkins have found that cancer cells can reprogram themselves to turn down their own energy-making machinery and use less oxygen, and that these changes might help cancer cells survive and spread.

8 May 2007

Kaposi's sarcoma-associated herpesvirus tricks cells to become tumors

Researchers at the University of Pennsylvania School of Medicine have discovered how the Kaposi's sarcoma-associated herpesvirus (KSHV) subverts a normal cell process in order to promote tumor growth.

8 Nov 2006