Life Science Articles

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AI in Forensic Science

This article describes the areas of forensic science that are changing due to artificial intelligence (AI) and machine learning.

8 Jan 2019

What is the CLARITY Technique?

CLARITY is a method used for the analysis of proteins and nucleic acid location within the brain.

9 Jan 2019

Protein A/G Purification for Antibodies

The protein A/G purification method is used to purify monoclonal IgA and IgG antibodies using a recombinant of Protein A and Protein G.

9 Jan 2019

History of Electrochemistry

Electrochemistry refers to the study of the chemical processes that are responsible for the movement of electrons which, in turn, causes electricity.

9 Jan 2019

Transfer-PCR (tPCR) Applications

In tPCR, target DNA is amplified and integrated into a destination vector in a single tube, without the need to purify the intermediate PCR product.

9 Jan 2019

How are Antibodies Validated?

Antibody validation ensures that antibodies are selective, reproducible, and specific enough for their application.

8 Jan 2019

HEK293 Cells: Applications and Advantages

Human embryonic kidney 293 (HEK293) cells are one of the most common cell lines used for research purposes. This article examines why they are so popular.

8 Jan 2019

CLARITY Methodology

The CLARITY technique is a method used to clear tissues of lipids and enable immunolabelling of whole, intact organs.

8 Jan 2019

Amyloid Cascade Hypothesis

The amyloid cascade hypothesis postulates that the initial event which triggers neuronal degradation in Alzheimer’s disease is enhanced amyloid-β generation and aggregation.

8 Jan 2019

Structure-based Protein Function Prediction

Studying the structure and shape of a protein, rather than its sequence, is considered to be an eloquent way of determining function.

4 Jan 2019

Ribosome Display: Applications in Research

Ribosome display is an in vitro protein evolution technique used to identify proteins which bind strongly to a target.

4 Jan 2019

Nanoparticles in Food and Food Contact Materials

Nanoparticles have been used to improve the properties of food packaging. However, recent advancements in nanotechnology have led to some concerns regarding their use.

3 Jan 2019

Nanogel Applications in Biomedicine

Nanogels consist of a single or multiple types of nanoparticles that are surrounded by a cross-linked hydrophilic polymer network.

4 Jan 2019

What are Stromal Cells (Mesenchymal Stem Cells)?

Stromal cells, or mesenchymal stem cells, are non-hematopoietic, multipotent, self-renewable cells, which are capable of trilineage differentiation.

4 Jan 2019

Predicting Protein Function from DNA Sequences

This article describes the ways in which protein function can be determined from DNA sequences or mRNA.

4 Jan 2019

Hematopoietic Stem Cell (HSC) Assays

Identifying HSCs and determining their functionality is an important part of ensuring their safety in humans.

7 Jan 2019

Computational-based Approaches to Protein Function Prediction

The most effective way of determining protein structure from sequence alone is by using computational methods.

7 Jan 2019

Autophagy Regulation

Too much or too little autophagy has been linked to a number of diseases. It is therefore important that we understand the regulators of this process.

7 Jan 2019

Phage Display: Applications in Research

Phage display is an analytical technique used to study protein-protein interactions and the relationship between a protein and the encoding DNA.

7 Jan 2019

PBMCs: Applications in Research

PBMCs are currently being used for various research applications; including regenerative medicine, CAR-T cell therapy, and most recently, biomarker discovery.

7 Jan 2019