Beta-thalassemia is one of a group of hereditary blood conditions that result from reduced or absent synthesis of the beta-globin chain of the hemoglobin molecule. It occurs as the result of a point mutation or less commonly, a deletion in the gene that codes for the beta chain, on chromosome 11. It occurs in 1 of 10,000-100,000 people, depending on the ethnicity. It is inherited in an autosomal recessive manner. The symptoms vary from none to severe anemia.