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University of Tokyo team accelerates bacterial genome evolution in the lab

The genome structure — how genes are organized within DNA sequences in an organism — is fundamental to the processes and functions of organisms.

13 May 2025

DiffInvex identifies key genes driving chemotherapy resistance

Just as species adapt over generations, our body's cells accumulate DNA changes throughout life. Most are harmless, yet a few "driver" mutations give a cell a competitive edge and can spark cancer.

13 May 2025

Scientists capture first real time images of heart formation in mouse embryos

Researchers at UCL and the Francis Crick Institute have, for the first time, identified the origin of cardiac cells using 3D images of a heart forming in real-time, inside a living mouse embryo.

13 May 2025

Advanced microscopy reveals how hormonal fluctuations shape the brain

Hormone levels fluctuate like the tides, ebbing and flowing according to carefully orchestrated cycles.

13 May 2025

New light-based 3D printing technique advances tissue engineering

Researchers at the Terasaki Institute for Biomedical Innovation (TIBI) have developed a technique that could help advance treatments in tissue engineering.

13 May 2025

Study reveals key differences in health risks between males and females

The results of an international study led by researchers from Queen Mary University of London's Precision Healthcare University Research Institute (PHURI) shed new light the underlying biological mechanisms which cause differences in health risks, symptoms and outcomes between males and females.

13 May 2025

New brain network discovery could revolutionize depression diagnosis

In a comprehensive Genomic Press Commentary published today, researchers have identified what could be the first reliable biomarker for depression risk, potentially transforming how this devastating condition is identified and treated.

13 May 2025

Simple oral swab test could revolutionize IVF success rates

About 15 per cent of all couples of reproductive age are involuntarily childless. A major reason why so many need assisted reproduction is that nowadays more and more people are putting off starting a family.

13 May 2025

Exploring the role of RNA binding proteins and circular RNAs in cancer

The interaction between RNA-binding proteins (RBPs) and circular RNAs (circRNAs) has emerged as a key area of interest in understanding cancer biology.

12 May 2025

RANBP2 identified as key regulator in the progression of multiple solid tumors

The nuclear pore complex protein RANBP2 has emerged as a critical factor in the development and progression of various solid malignancies.

12 May 2025

Mitochondrial DNA editing offers new hope for neurodegenerative disease treatment

Mitochondrial DNA (mtDNA) editing has emerged as a revolutionary approach in the fight against neurodegenerative diseases (NDDs).

12 May 2025

Researchers uncover how Entamoeba histolytica evades the immune system

The single-celled parasite Entamoeba histolytica infects 50 million people each year, killing nearly 70,000. Usually, this wily, shape-shifting amoeba causes nothing worse than diarrhea.

12 May 2025

PhoreMost makes key appointments to Board to advance development of next-generation degrader therapeutics

PhoreMost Ltd., a next-generation targeted protein degradation (TPD) company progressing a pipeline of degrader therapeutics within oncology and inflammation, today announced Barbara Duncan has joined its Board as Chair, and Stephen Dilly as Non-Executive Director.

From PhoreMost 12 May 2025

ELRIG announces keynote speakers for Drug Discovery 2025

ELRIG, a not-for-profit, volunteer-led organization dedicated to the global drug discovery community, has revealed the keynote speakers for its flagship event, Drug Discovery 2025. Taking place at the ACC in Liverpool, UK from 21-22 October, the conference will feature presentations from Professor Heather Pinkett (Northwestern University) and Dr Dafydd Owen (Pfizer Medicine Design).

From ELRIG (UK) Ltd. 12 May 2025

DNA strand separation requires more force in crowded cellular environments

By creating a more true-to-life representation of DNA's environment, researchers at Northwestern University have discovered that strand separation - the essential process a "resting" double helix undergoes before it can initiate replication or make repairs - may take more mechanical force than the field previously believed.

11 May 2025

Newly identified gene mutation causes severe form of Fanconi anemia

Fanconi anemia is an aggressive, life-threatening disorder. Most individuals living with this rare genetic condition, characterized by bone marrow failure and cancer predisposition, survive into adulthood only with bone marrow transplantation and regular cancer screening.

11 May 2025

Machine learning model guides smarter gene selection in newborn screening

More than a decade ago, researchers launched the BabySeq Project, a pilot program to return newborn genomic sequencing results to parents and measure the effects on newborn care.

10 May 2025

Unlocking the mechanism behind marine bacterium’s ability to clean up oil spills

The marine bacterium Alcanivorax borkumensis feeds on oil, multiplying rapidly in the wake of oil spills, and thereby accelerating the elimination of the pollution, in many cases.

10 May 2025

Why your baby’s first steps may be written in their DNA

Researchers identified 11 genetic loci linked to the age at which infants start walking, revealing that this milestone is influenced by thousands of common genetic variants. These genetic factors also correlate with brain development, cognitive traits, and neurodevelopmental conditions like ADHD.

8 May 2025

Mature liver cells trigger regeneration in response to neighboring injury

Acetaminophen is the most frequently taken fever and pain medication worldwide, but overdosing can be toxic to liver cells. In the United States, about 1,600 cases of acute liver failure and 500 deaths occur each year due to acetaminophen overuse and liver failure.

8 May 2025