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Using Q-bodies for imaging intracellular proteins in live cells

Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development.

9 Sep 2022

Study helps understand how dietary therapies work for epilepsy

Calorie restriction has long been associated with reduced seizures in epilepsy. New research from Boston Children's Hospital helps explain how fasting affects neurons in the brain and could lead the way to new approaches that would avoid the need for fasting or restrictive diets. The findings were published August 30 in the journal Cell Reports.

9 Sep 2022

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

9 Sep 2022

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

A Penn State-led team of interdisciplinary researchers has developed techniques to improve the efficiency of CRISPR-Cas9, the genome editing technique that earned the Nobel Prize in 2020.

9 Sep 2022

Scientists observe how SARS-CoV-2 protein dismantles critical immunity pathway

Over the past two years, scientists have studied the SARS-CoV-2 virus in great detail, laying the foundation for developing COVID-19 vaccines and antiviral treatments.

9 Sep 2022

New data analysis approach could help uncover the genetic basis of many diseases

In the era of Big Data, obtaining a huge amount of information is the easy part; knowing what to do with it is another story entirely.

9 Sep 2022

The use of AlphaFold2-enabled molecular docking simulations to predict protein-ligand interactions for antibiotic drug discovery

Researchers demonstrated that advances in modeling protein-ligand interactions using machine learning-based approaches are needed to exploit AlphaFold2 for antibiotic discovery better.

9 Sep 2022

MolGen Joins Life Sciences & Health Dutch Economic Mission to California

MolGen B.V. of Veenendaal (NL), participates in the 24th Annual Conference of the European Society for Clinical Virology (ESCV) held in Manchester, United Kingdom on 7-10 September 2022.

From MolGen 9 Sep 2022

Intelligent fluorescent microscope for imaging biological events in detail

Imagine you're a PhD student with a fluorescent microscope and a sample of live bacteria. What's the best way use these resources to obtain detailed observations of bacterial division from the sample?

9 Sep 2022

All SARS-CoV-2 variants neutralized by a potent new antibody

Researchers describe a mouse model used to generate a VH1-2 heavy chain (HC)- and Vκ1-33 light chain (LC)-based recombinant antibody that broadly neutralized all severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants, including the newly emergent Omicron sub-variant BA.5.

9 Sep 2022

A single genomic change may have given modern humans an advantage over Neanderthals

A single amino acid change in the transketolase-like 1 (TKTL1) protein may have given modern humans an advantage over more ancient contemporaries like Neanderthals by enabling increased neocortical neurogenesis, researchers report.

9 Sep 2022

Stem cell-derived liver cell model could be a valuable tool for future studies on Ebola virus

Ebola virus causes serious infections in humans and in fatal cases, damage and dysfunction of the liver is often present, suggesting that the liver plays a decisive role in disease outcome.

8 Sep 2022

Licorice compounds proposed as effective candidates for treatment of COVID-19

Researchers describe the different mechanisms by which licorice active ingredients target SARS-CoV-2.

8 Sep 2022

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.

8 Sep 2022

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Based on findings from a new study by a Johns Hopkins Medicine-led research team, an effective means of fighting SARS-CoV-2, the virus that causes COVID-19, may be possible that circumvents the problem of waning immunity often observed when current vaccines deal with emerging COVID variants.

8 Sep 2022

Life Science News

Using Q-bodies for imaging intracellular proteins in live cells

Study helps understand how dietary therapies work for epilepsy

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

Scientists observe how SARS-CoV-2 protein dismantles critical immunity pathway

New data analysis approach could help uncover the genetic basis of many diseases

The use of AlphaFold2-enabled molecular docking simulations to predict protein-ligand interactions for antibiotic drug discovery

MolGen Joins Life Sciences & Health Dutch Economic Mission to California

Intelligent fluorescent microscope for imaging biological events in detail

All SARS-CoV-2 variants neutralized by a potent new antibody

A single genomic change may have given modern humans an advantage over Neanderthals

Stem cell-derived liver cell model could be a valuable tool for future studies on Ebola virus

Licorice compounds proposed as effective candidates for treatment of COVID-19

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Promising anti-cancer agent may also prevent SARS-CoV-2 from replication

Researchers harness stem cells to study how Ebola virus infects and damages the liver

Pitt researchers describe a pathway by which cells repair damaged lysosomes

Plants and plant-derived preparations as co-treatments for COVID-19

Insights into molecular structure of protein assembly that plays key role in controlling cristae architecture

Researchers identify DNA regions associated with physical activity or leisure screen time

Evolving spectrophotometry for modern biopharma workflows

Scaling B-cell cloning workflows for antibody development

Fluidics in Modern Healthcare & Medical Device Innovation

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