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Researchers discover how a genetic mutation in mice and monkeys interferes with viruses

A nationwide team of researchers, led by scientists at University of Utah Health and The Rockefeller University, has determined how a genetic mutation found in mice and monkeys interferes with viruses such as HIV and Ebola.

30 Sep 2021

Study reveals how to improve overall immune response against virally driven cancers

Blocking the PD-1 inhibitory pathway within a subset of specialized T-cells may improve overall immune response against virally driven cancers, according to findings published in Nature.

30 Sep 2021

Researchers develop fluorescence quenching assay to probe the integrity of cell membrane coating

Cell membrane coated biomimetic nanoparticles (NPs) have been widely studied in nanomedicine because of their unique properties such as immune escaping, long blood circulation, specific molecular recognition and efficient cancer targeting, indicating a great potential in targeted cancer therapy.

30 Sep 2021

Gyros Protein Technologies introduces Gyrolab AAV9 Titer Kit to support AAV-based cell and gene therapy production

Gyros Protein Technologies AB today announced the introduction of Gyrolab® AAV9 Titer Kit for rapid determination of titer in AAV9 vector-based cell and gene therapy manufacturing.

From Gyros Protein Technologies AB 30 Sep 2021

Scientists use new technique to study the effects of reactive electrophilic drugs

In 2014, the European Medicines Agency approved the drug Tecfidera for the treatment of relapsing multiple sclerosis, a neurodegenerative disease that affects millions of people worldwide. In multiple sclerosis, inflammation damages the protective myelin insulation around nerves, and the nerves themselves.

30 Sep 2021

Researchers develop novel antibacterial material for wound dressing

Researchers at the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague) and the Technical University of Liberec in collaboration with researchers from the Institute of Microbiology of the CAS, the Department of Burns Medicine of the Third Faculty of Medicine at Charles University (Czech Republic), and P. J. Šafárik University in Košice (Slovakia) have developed a novel antibacterial material combining nonwoven nanotextile and unique compounds with antibacterial properties.

30 Sep 2021

Hippocampus connects separate, distant events to form narrative memories, study shows

People love stories. We find it easier to remember events when they are part of an overarching narrative. But in real life, the chapters of a story don't follow smoothly one from another. Other things happen in between.

30 Sep 2021

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

One of modern biologists' most ambitious goals is to learn how to expand or otherwise modify the genetic code of life on Earth, in order to make new, artificial life forms.

30 Sep 2021

New system synthetically reconnects neural circuits using neuropeptides from Hydra

For two people to communicate in a loud, crowded room, they need to be standing side by side. The same is often true for neurons in the brain. But the same way a cell phone allows two people to communicate clearly across the room, new research at the Marine Biological Laboratory (MBL) opened up a new channel of communication in the worm C. elegans brain.

30 Sep 2021

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

Worms don't wiggle when they have Alzheimer's disease. Yet something helped worms with the disease hold onto their wiggle in Professor Jessica Tanis's lab at the University of Delaware.

29 Sep 2021

RIT part of NSF-funded project to design futuristic materials inspired by biological cells

Rochester Institute of Technology Associate Professor Moumita Das is part of a team of researchers that was recently awarded a $1.8 million grant from the National Science Foundation to design and create next-generation materials inspired and empowered by biological cells.

29 Sep 2021

Yale researchers uncover how the brain takes shape during mid-pregnancy

About four or five months after conception, a burst of synaptic growth begins in the prefrontal cortex (PFC) of the human fetus.

29 Sep 2021

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

After a gene is transcribed into RNA, modifications can occur to the subunits or "bases" that make up the RNA molecule, which can affect its structure and function. The study of these changes is known as "epitranscriptomics." These base modifications can occur to most types of RNA molecules, including microRNAs.

29 Sep 2021

Study explores ways to reduce sodium in bread without sacrificing taste and leavening ability

Most people in the U.S. consume too much salt; adult Americans typically eat twice the daily amount recommended by dietary guidelines.

29 Sep 2021

Aptamer Group collaborates with BizCom to market Optimer discovery and development services in Japan

Aptamer Group and BizCom announce collaboration for Optimer distribution and marketing services in Japan.

From Aptamer Group 29 Sep 2021

Novel strategy for in vitro cell-selective protection has potential for use in adoptive cell therapy

Adoptive cell therapy (ACT) is an emerging powerful cancerimmunotherapy, which includes a complex process of genetic modification, stimulation and expansion. During invitroorexvivomanipulation, sensitive cells are inescapably subjected to harmful external stimuli. Although a variety ofcytoprotectionstrategies have been developed, their application on ACT remains challenging.

29 Sep 2021

Two proteins joined together using a free-standing, rigid link

Researchers at the Paul Scherrer Institute PSI are the first to have joined two proteins together by means of a free-standing, rigid link. The structural element holds the two protein molecules together at a defined distance and angle, much the way a barbell handle connects two weights.

29 Sep 2021

The new FlowCam® LO improves particle characterization in drug development

Yokogawa Fluid Imaging Technologies announces the release of the FlowCam® LO, the first and only light obscuration instrument with imaging capabilities.

From Yokogawa Fluid Imaging Technologies, Inc. 29 Sep 2021

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Amyotrophic lateral sclerosis (ALS) is an intractable neurological disease. Aging is a risk factor for the accumulation of TDP-43 (transduction responsive region DNA-binding protein of 43kDa) in the motor cortex. TDP-43 is a protein that tends to accumulate in increasing amounts, and the amount is strictly controlled by the splicing of TDP-43. Through cell experiments and analysis of human brain tissue, researchers at Brain Research Institute, Niigata University, led by Akihiro Sugai, M.D., Ph.D., have found that methylation of TDP-43 DNA is involved in the background of motor cortex involvement with aging in ALS

29 Sep 2021

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Oncotarget published "Pan-drug and drug-specific mechanisms of 5-FU, irinotecan (CPT-11), oxaliplatin, and cisplatin identified by comparison of transcriptomic and cytokine responses of colorectal cancer cells" which reported that there was an increase in IL-8 by oxaliplatin and increase in ferritin by cisplatin which may contribute to cancer cell survival.

29 Sep 2021

Life Science News

Researchers discover how a genetic mutation in mice and monkeys interferes with viruses

Study reveals how to improve overall immune response against virally driven cancers

Researchers develop fluorescence quenching assay to probe the integrity of cell membrane coating

Gyros Protein Technologies introduces Gyrolab AAV9 Titer Kit to support AAV-based cell and gene therapy production

Scientists use new technique to study the effects of reactive electrophilic drugs

Researchers develop novel antibacterial material for wound dressing

Hippocampus connects separate, distant events to form narrative memories, study shows

Researchers supplement synthetic biology toolkit to streamline investigations into genetic code expansion

New system synthetically reconnects neural circuits using neuropeptides from Hydra

Wiggling worms offer new clues into the potential impact of diet on Alzheimer's

RIT part of NSF-funded project to design futuristic materials inspired by biological cells

Yale researchers uncover how the brain takes shape during mid-pregnancy

Researchers detect two types of RNA base modifications simultaneously using a quantum sequencer

Study explores ways to reduce sodium in bread without sacrificing taste and leavening ability

Aptamer Group collaborates with BizCom to market Optimer discovery and development services in Japan

Novel strategy for in vitro cell-selective protection has potential for use in adoptive cell therapy

Two proteins joined together using a free-standing, rigid link

The new FlowCam® LO improves particle characterization in drug development

Methylation of TDP-43 DNA linked to age-dependent motor cortex involvement in ALS

Researchers compare transcriptomic and cytokine responses of colorectal cancer cells

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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