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Using AI to foster productivity in pharmaceutical research and development

As part of our SLAS Europe 2022 coverage, we speak to Sree Vadlamudi from Iktos, about how we can adopt AI to help foster productivity within pharmaceutical research.

From Society for Laboratory Automation and Screening (SLAS) 25 Aug 2022

Soft-tissue sarcomas produce a protein that make immune cells 'go bad'

Investigators from Cedars-Sinai Cancer have discovered that cancerous tumors called soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting.

24 Aug 2022

Study shows how Klebsiella pneumoniae suppresses the body's defenses

New research published in Cell Reports has shown how the bacterium Klebsiella pneumoniae suppresses our body's defences, resulting in it being unable to clear infection.

24 Aug 2022

Using the power of CRISPR to engineer better, stronger, longer-lived T cells

T cells used in immunotherapy treatments can get exhausted by the task of fighting cancer cells or get shutdown as they enter tumors.

24 Aug 2022

Optimized human small intestinal organoids can help better study the functioning of small intestines

Researchers from the Organoid group (formerly the Clevers group) have improved human small intestinal organoids – miniature versions of the small intestine.

24 Aug 2022

CRISPR genome-editing technology can be used as a tool to discover RNA therapeutics for lung cancer

An international team of scientists have demonstrated for the first time that CRISPR genome-editing technology can be used as a tool to find new gene therapies for lung cancer.

24 Aug 2022

Reservoir ensures sustainable use of reagents

Manufactured to the ANSI/SLAS standard, the range of reagent reservoirs from Porvair Sciences are designed for simple integration into any automated liquid handling system.

From Porvair Sciences Limited 24 Aug 2022

Biological effects of nanoplastics in paints

A recent study analyzed paint composition and its biological properties, as paints release polymers and particles into the environment.

24 Aug 2022

Strong facial similarity in people is linked with shared genetic variants

A collection of photos of genetically unrelated lookalikes, along with DNA analysis, revealed that strong facial similarity is associated with shared genetic variants.

23 Aug 2022

Glucokinase activator AZD1656 shows potential benefit for diabetics with moderate to severe COVID-19

A new study examines the potential benefit of the glucokinase activator molecule AZD1656 in the ARCADIA trial.

23 Aug 2022

Unconventional T cells influence immune responses in the lymph nodes

Lymph nodes trigger very different immune responses – depending on which body tissue they are connected to. Special T cells are responsible for this newly discovered relation.

23 Aug 2022

Lack of sleep leads to withdrawal of willingness to help other people

Humans help each other - it's one of the foundations of civilized society. But a new study by scientists at the University of California, Berkeley, reveals that a lack of sleep blunts this fundamental human attribute, with real-world consequences.

23 Aug 2022

UCI study uncovers key insights into 'parasitic genes'

They are considered "parasitic genes." Even though they comprise over half of human DNA, much remains to be learned about them.

23 Aug 2022

Wyss Institute's DNA nanotechnology-driven SPEAR protein-detection technology licensed to Spear Bio

Today, the Wyss Institute for Biologically Inspired Engineering at Harvard University and Spear Bio, Inc.announced that the Institute's DNA nanotechnology-driven ultrasensitive SPEAR protein-detection technology has been licensed to the newly formed Boston-based startup.

23 Aug 2022

Enriched environment influences maternal nurturance, lactation quality, and offspring development in rats

Rat mothers in enriching environments give birth to larger offspring, are more efficient parents, and have heartier breastmilk, compared to mothers in standard laboratory housing, according to research published in eNeuro.

23 Aug 2022

Common molecular tool for DNA labelling shows unexpected anticancer properties

Scientists at the UNC School of Medicine have made the surprising discovery that a molecule called EdU, which is commonly used in laboratory experiments to label DNA, is in fact recognized by human cells as DNA damage, triggering a runaway process of DNA repair that is eventually fatal to affected cells, including cancer cells.

23 Aug 2022