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LJI scientists uncover major clue toward developing new antiviral therapies against flaviviruses

Zika virus has a trick up its sleeve. Once inside the body, the virus likes to make a bee line for dendritic cells, the cells we rely on to launch an effective immune response.

12 Sep 2022

Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease.

12 Sep 2022

Neuroscientists reveal precise connections between retinal nerve cells and the midbrain structure

For the first time, neuroscientists from Charité – Universitätsmedizin Berlin and the Max Planck Institute for Biological Intelligence (currently in the process of being established) have revealed the precise connections between sensory neurons inside the retina and the superior colliculus, a structure in the midbrain.

12 Sep 2022

Scientists estimate the impact of genetic risk factors on the loss of healthy life years

Researchers have, for the first time, systematically estimated the impact of a range of different disease-associated genetic risk factors on the loss of healthy life years. Knowing the contribution of different genetic risk factors on disease burden can help prioritise and design interventions using genetic information.

12 Sep 2022

Morning-loaded and evening-loaded diets produce similar weight loss, with no energy metabolism differences

There's the old saying in dieting that one must "breakfast like a king, lunch like a prince, and dine like a pauper," based on the belief that consuming the bulk of daily calories in the morning optimizes weight loss by burning calories more efficiently and quickly.

12 Sep 2022

Self-replicating intradermal RNA vaccine against SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, researchers assessed the efficiency of a controllable self-replicating ribonucleic acid (c-srRNA) vaccine against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

12 Sep 2022

Jumping gene plays an important role in reducing depression, fear, and anxiety

First characterized in Prof. Tadashi Yamamoto's former lab in Japan in 1996, the gene Tob is well known for the role it plays in cancer. Previous research has also indicated that it has a hand in regulating the cell cycle and the body's immune response.

9 Sep 2022

Label-free trace detection of bio-molecules by LI-SERS method

A new publication from Opto-Electronic Advances; DOI 10.29026/oea.2022.210121 discusses label-free trace detection of bio-molecules by liquid-interface assisted surface-enhanced Raman scattering using a microfluidic chip.

9 Sep 2022

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

A team of researchers from the IIT-Istituto Italiano di Tecnologia (Italian Institute of Technology) has designed in silico "molecular probes" able to track the progress of a protein that misbehaves in different neurodegenerative diseases, such as Amyotrophic Lateral Sclerosis (ALS) and Fronto-Temporal Dementia (FTD).

9 Sep 2022

Duke researchers identify chlamydia’s stealthy cloaking device

Chlamydia, the leading cause of sexually transmitted bacterial infections, evades detection and elimination inside human cells by use of a cloaking device. But Duke University researchers have grasped the hem of that invisibility cloak and now hope they can pull it apart.

9 Sep 2022

Ground-breaking plastic film can kill viruses that land on its surface with room light

Researchers at Queen's University Belfast have developed a ground-breaking plastic film that can kill viruses that land on its surface with room light.

9 Sep 2022

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Using a genetic screening platform developed by a UT Southwestern Nobel Laureate, scientists with the Center for the Genetics of Host Defense at UT Southwestern Medical Center have identified genetic mutations that contribute to nonalcoholic fatty liver disease (NAFLD), providing a potential future target for therapeutic interventions.

9 Sep 2022

Understanding the molecular pathways that underly nutrient switch in starving cancer cells

Cancer cells often grow in environments that are low in nutrients, and they cope with this challenge by switching their metabolism to using proteins as alternative "food".

9 Sep 2022

NIH funds $3.35 million to enhance diversity in genomics training

The National Human Genome Research Institute (NHGRI), part of the National Institutes of Health, will fund $3.35 million over five years to launch the Genome Research Experiences to Attract Talented Undergraduates into the Genomics Field to Enhance Diversity (GREAT) program.

9 Sep 2022

Researchers produce high-resolution crystal structure of enzyme critical to SARS-CoV-2 survival

A team of Mount Sinai researchers has produced a high-resolution crystal structure of an enzyme essential to the survival of SARS-CoV-2, the virus that causes COVID-19.

9 Sep 2022

Using Q-bodies for imaging intracellular proteins in live cells

Recent advances in imaging technology have made it possible to visualize intracellular dynamics, which offers a better understanding of several key biological principles for accelerating therapeutic development.

9 Sep 2022

Study helps understand how dietary therapies work for epilepsy

Calorie restriction has long been associated with reduced seizures in epilepsy. New research from Boston Children's Hospital helps explain how fasting affects neurons in the brain and could lead the way to new approaches that would avoid the need for fasting or restrictive diets. The findings were published August 30 in the journal Cell Reports.

9 Sep 2022

Life Science News

LJI scientists uncover major clue toward developing new antiviral therapies against flaviviruses

Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

Neuroscientists reveal precise connections between retinal nerve cells and the midbrain structure

Scientists estimate the impact of genetic risk factors on the loss of healthy life years

Morning-loaded and evening-loaded diets produce similar weight loss, with no energy metabolism differences

Self-replicating intradermal RNA vaccine against SARS-CoV-2

Jumping gene plays an important role in reducing depression, fear, and anxiety

Label-free trace detection of bio-molecules by LI-SERS method

Molecular probes can track the progress of protein that misbehaves in neurodegenerative diseases

Duke researchers identify chlamydia’s stealthy cloaking device

Ground-breaking plastic film can kill viruses that land on its surface with room light

UT Southwestern scientists identify genetic mutations that contribute to nonalcoholic fatty liver disease

Understanding the molecular pathways that underly nutrient switch in starving cancer cells

NIH funds $3.35 million to enhance diversity in genomics training

Researchers produce high-resolution crystal structure of enzyme critical to SARS-CoV-2 survival

Using Q-bodies for imaging intracellular proteins in live cells

Study helps understand how dietary therapies work for epilepsy

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Novel method for gene editing of hPSCs yields up to 84% knockout efficiency

Scientists observe how SARS-CoV-2 protein dismantles critical immunity pathway

Real-time Raman monitoring for pharmaceutical hot melt extrusion

Synthetic Psychedelics: A Growing Public Health Concern

How the Vutara VXL simplifies single-molecule imaging

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