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Horizontal gene transfer between viruses and hosts plays a major role in driving evolution

The first comprehensive analysis of viral horizontal gene transfer (HGT) illustrates the extent to which viruses pick up genes from their hosts to hone their infection process, while at the same time hosts also co-opt useful viral genes.

5 Jan 2022

Scientists unravel how LPS prevents or promotes development of allergic disease

Immunologists have long been baffled by LPS, the bacterial lipopolysaccharide that helps form the cell walls of Gram-negative bacteria.

5 Jan 2022

New compound could combat multidrug-resistant pathogens in healthcare settings

For years, public-health experts have been sounding the alarm about the next phase in humanity's co-existence with bacteria - a dark future where emerging strains have rendered once-powerful antibiotics useless.

5 Jan 2022

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

A folic acid-like drug, L-methylfolate, when administered alongside the standard therapy for patients with recurrent glioblastoma, changed aDNA process within their brain tumors, according to results from a phase 1 clinical trial.

5 Jan 2022

Anti-fogging sprays and cloths may contain high levels of PFAS, finds study

The anti-fogging sprays and cloths many people use to prevent condensation on their eyeglasses when wearing a mask or face shield may contain high levels of per- and polyfluorinated alkyl substances (PFAS), a new Duke University-led study finds.

5 Jan 2022

Researchers discover how oral bacteria increase vulnerability to infection

Researchers from the University of Louisville School of Dentistry and their colleagues have discovered details of how proteins produced by oral epithelial cells protect humans against viruses entering the body through the mouth.

5 Jan 2022

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

Study uncovers a harmful neutrophil behavior linked to cardiovascular disease

Scientists led by Dr. Andrés Hidalgo at the Centro Nacional de Investigadores Cardiovasculares have discovered that circulating neutrophils - a type of immune cell - acquire different behavior patterns during inflammatory processes.

5 Jan 2022

NRL researchers aim to advance understanding of how cells organize and communicate

U.S. Naval Research Laboratory researchers in the Chemistry Division apply their knowledge of biology in conjunction with materials to improve understanding of how cells and tissues organize and apply new methods to affect cell communication.

5 Jan 2022

Integrin/TGF-β1 inhibitors highly effective in attenuating COVID-19 severity

New study results suggest that integrin inhibitors have the potential to both prevent infection with SARS-CoV-2, including the Delta and Omicron variants, and to decrease TGF-β levels, resulting in a decrease in COVID-19 severity, hospitalization, and death, especially in vulnerable and unvaccinated populations.

5 Jan 2022

Statistical analysis reveals less severe COVID-19 outcome due to Omicron variant

A new study demonstrated that in the US, the COVID-19 cases arising after the emergence of the SARS-CoV-2 Omicron variant showed reduced severity of infection than in the cases recorded in previous time points (during the Delta variant outbreak).

5 Jan 2022

Unique nanoparticle can deliver genome editing technology to endothelial cells

The lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls.

4 Jan 2022

Novel insight into the immune characteristics of bats

Many studies have indicated that bats are significant reservoirs of innumerable viruses, such as influenza, coronaviruses, and rabies. These studies have also reported that bats predominantly remain asymptomatic or develop mild diseases during viral infections caused by henipaviruses, Ebola virus, coronaviruses, etc.

4 Jan 2022

Empire Discovery Institute collaborates with Novo Nordisk to launch new drug discovery initiative

Empire Discovery Institute entered into a five-year collaborative research partnership with global pharmaceutical company Novo Nordisk A/S to launch LeapRx, a new initiative where EDI and Novo Nordisk will co-invest, incubate and accelerate innovative drug discovery and development projects from its academic partners.

4 Jan 2022

Research provides compelling insights into the complex nature of genomic imprinting in mice

Mammalian offspring inherit two versions, or alleles, of each gene with one allele from each biological parent. However, gene expression is tightly regulated and certain genes undergo the phenomenon of "genomic imprinting", which is where only the allele received by the male or the female parent is expressed.

4 Jan 2022

Oxford researchers demonstrate the feasibility of increasing the speed and volume of vaccine production

The University of Oxford's vaccine manufacturing research team has today published a pre-print paper demonstrating the feasibility of a step change in the speed and volume of production of adenovirus-vectored vaccines against new virus variants or other future pandemics.

4 Jan 2022

Experts cautiously optimistic about risks of Delta-Omicron mutations mix

Researchers evaluate the risk of the P681R, N501Y, and D614G mutations of current interest co-occurring naturally due to convergent evolution.

4 Jan 2022

Sino Biological Establishes New Location in Houston, Texas

Sino Biological, Inc. (“Sino Biological” or the “Company”), a biotechnology company listed on ChiNext (SZSE: 301047), provides biological research reagents and related technical contract research services, is pleased to announce its physical geographic expansion, adding a new location in Houston, Texas.

From Sino Biological Inc. 4 Jan 2022

Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources

Sino Biological, Inc. (SZSE: 301047) has recently deposited reagents for the Omicron variant, including recombinant proteins to Spike and Nucleocapsid, and antibody products to BEI Resources, a central repository for reagents to support infectious disease research.

From Sino Biological Inc. 4 Jan 2022

SARS-CoV-2 differs from other betacoronaviruses in a key IRE1α/XBP1 pathway

SARS-CoV-2 differs from other viruses in the beta coronavirus family in the activation of a key pathway associated with endoplasmic reticulum stress.

3 Jan 2022

Life Science News

Horizontal gene transfer between viruses and hosts plays a major role in driving evolution

Scientists unravel how LPS prevents or promotes development of allergic disease

New compound could combat multidrug-resistant pathogens in healthcare settings

Folic acid-like drug reprograms DNA methylome of aggressive brain tumors

Anti-fogging sprays and cloths may contain high levels of PFAS, finds study

Researchers discover how oral bacteria increase vulnerability to infection

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

Study uncovers a harmful neutrophil behavior linked to cardiovascular disease

NRL researchers aim to advance understanding of how cells organize and communicate

Integrin/TGF-β1 inhibitors highly effective in attenuating COVID-19 severity

Statistical analysis reveals less severe COVID-19 outcome due to Omicron variant

Unique nanoparticle can deliver genome editing technology to endothelial cells

Novel insight into the immune characteristics of bats

Empire Discovery Institute collaborates with Novo Nordisk to launch new drug discovery initiative

Research provides compelling insights into the complex nature of genomic imprinting in mice

Oxford researchers demonstrate the feasibility of increasing the speed and volume of vaccine production

Experts cautiously optimistic about risks of Delta-Omicron mutations mix

Sino Biological Establishes New Location in Houston, Texas

Sino Biological Deposits Recombinant Omicron Proteins and Antibodies to BEI Resources

SARS-CoV-2 differs from other betacoronaviruses in a key IRE1α/XBP1 pathway

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research

How GLP‑1 Agonists Are Shaping the Future of Obesity Treatment With Dr Bryony Henderson

Flow chemistry, AI, and NMR: A next-gen approach to scalable API production

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